The Memory clinic platform is a MultiPark infrastructure which facilitates research projects run by clinical researchers performing studies on dementia disorders. This platform consists of trained research nurses, medical doctors and administrators, who perform in-depth assessments of neurological, cognitive and psychiatric functions of study participants. Further, the research staff can also coll

https://www.multipark.lu.se/infrastructures/memory-clinic-platform - 2025-06-05

The Neuroimaging platform facilitates research projects in humans using CT, MRI and PET-CT at state of the art equipment including top-end digital PET scanners, 3T MRI and the national 7T MRI (LBIC). While the equipment is located at and run mainly by the clinical imaging department at Skane University Hospital, the platform consists of core staff for image analysis and a lecturer performing resea

https://www.multipark.lu.se/infrastructures/neuroimaging-platform - 2025-06-05

Below are the minutes and appendices from MultiPark´s board meetings. Please click on the following dates to download the minutes of the corresponding board meetings. 20252025-05-23 MultiPark board minutes2025-02-19 MultiPark board minutes20242024-11-21 MultiPark board minutes2024-09-12 MultiPark board minutes2024-05-22 MultiPark board minutes2024-02-19 MultiPark board minutes 20232023-11-21 Multi

https://www.multipark.lu.se/board-meeting-minutes - 2025-06-05

AAV platform report 2021 Bacteria lab & retroviral production report 2021 Behavioral mouse platform report 2021 Behavioral rat platform report 2021 Behavioral terminal platform report 2021 Biobank Sample Collection (MPBC) report 2021 Bioinformatics, genetics report 2021 Cellomics platform report 2021 Confocal microscope, A10 report 2021 Confocal microscope, A11 report 2021 FACS Aria III report 202

https://www.multipark.lu.se/infrastructure-reports-2021 - 2025-06-05

MultiPark strategic plan 2020-2025

https://www.multipark.lu.se/research/multipark-strategic-plan-2020-2025 - 2025-06-05

Information on the mouse behavioral platform Test rooms and bookingThe mouse behavioral platform comprises the following test rooms:BMC room C1042:(front) Flexible space module for motor tests including rotarod, corridor test, grip strength meter, cylinder test (equipped with mirrors and mobile videocamera).(back) Open field video-tracking system for 8 boxes.BMC room C1044: (front) Flexible space

https://www.multipark.lu.se/infrastructures/behavioral-platform/mouse-behavioral-platform - 2025-06-05

Rules of procedure for MultiPark

https://www.multipark.lu.se/about-multipark/multipark-steering-document - 2025-06-05

On this page, the Gender and Politics research group (GPRG) is presented, including the conveners, researchers in the group, and upcoming seminars. About the groupThe Gender and Politics research group brings together lecturers and researchers who think of gender as a central analytical lens through which power, institutions, norms and identities should be studied.Gender is increasingly prominent

https://www.svet.lu.se/en/research/research-groups/gender-and-politics-research-group - 2025-06-05

STVC75 – Bachelor course in Political science (7.5 credits). This course focuses on local politics and administration in democratic systems in a comparative perspective. The course includes web-based elements in collaboration with other European universities. Empirically, the approach is a comparative perspective on the organizing principles and primary activities of the local public sector as wel

https://www.svet.lu.se/en/education/international-opportunities/exchange-students-coming-sweden/bachelor-courses/local-government-comparative-perspective - 2025-06-05

Spring 2025 The Higher Research Seminar is the main collective seminar of the department. The research staff and invited national and international leading scholars present ongoing research and analyses of a broad range of exciting topics of relevance for Political Science. The seminar is held on Wednesdays 13.15 to 14.30 in Eden 367, unless otherwise indicated. PhD mid-term seminars 13:15 to 14:4

https://www.svet.lu.se/en/higher-research-seminar - 2025-06-05

In June 2022, Sofia Bergh started her PhD studies in TNU supervised by Prof. Åsa Petersén. The overall aim of the PhD project is to investigate the cellular and molecular mechanisms of limbic system pathology of Huntington’s disease. Her first original research article is in press titled “Effects of mutant huntingtin in oxytocin neurons on non-motor features of Huntington’s disease” in Neuropathol

https://www.huntington-research.lu.se/team/sofia-bergh-phd-student - 2025-06-05

Weydt P, Dupuis L and Petersen Å. Handbook of Clinical Neurology 157: 761-775 (2018) Abstract Huntington disease (HD) is a paradigmatic autosomal-dominant adult-onset neurodegenerative disease. Since the identification of an abnormal expansion of a trinucleotide repeat tract in the huntingtin gene as the underlying genetic defect, a broad range of transgenic animal models of the disease has become

https://www.huntington-research.lu.se/thermoregulatory-disorders-huntington-disease - 2025-06-05

Baldo B, Soylu R and Petersén ÅPLoS One 8(12) (2013)AbstractHuntington's disease (HD) is a fatal neurodegenerative disorder caused by an expanded polyglutamine repeat in the huntingtin protein. Neuropathology in the basal ganglia and in the cerebral cortex has been linked to the motor and cognitive symptoms whereas recent work has suggested that the hypothalamus might be involved in the metabolic

https://www.huntington-research.lu.se/maintenance-basal-levels-autophagy-huntingtons-disease-mouse-models-displaying-metabolic-dysfunction - 2025-06-05

Bergh S, Gabery S, Tonetto S, Kirik D, Petersén Å and Cheong RY. Neuropathology and Applied Neurobiology. 2023;49(2):e12891. doi:10.1111/nan.12891 [published correction appears in Neuropathol Appl Neurobiol. 2023 Jun;49(3):e12905]. Abstract Background: Early non-motor features including anxiety, depression and altered social cognition are present in Huntington's disease (HD). The underlying neurob

https://www.huntington-research.lu.se/effects-mutant-huntingtin-oxytocin-neurons-non-motor-features-huntingtons-disease - 2025-06-05

In May 2022, Karin Dalene Skarping started her PhD studies in TNU supervised by Prof. Åsa Petersén. The overall aim of the PhD project is to study genetic mechanisms that may modify the disease course and pathology of Huntington disease. One of her current research projects is aimed to examine associations between germline pathogenic variants in mismatch-repair (MMR) genes and CAG-repeats in HTT,

https://www.huntington-research.lu.se/team/karin-dalene-skarping-phd-student - 2025-06-05

Sofia Hult Lundh1, Nathalie Nilsson1, Rana Soylu1, Deniz Kirik2 and Åsa Petersén1.1Translational Neuroendocrine Research Unit, Department of Experimental Medical Science, Lund University, Lund SE-221 84, Sweden.2Brain Repair and Imaging in Neural Systems (BRAINS) Unit, Department of Experimental Medical Science, Lund University, Lund SE-221 84, Sweden.Human Molecular Genetics 22: 3485-3497 (2013)A

https://www.huntington-research.lu.se/hypothalamic-expression-mutant-huntingtin-contributes-development-depressive-behavior-bac-transgenic - 2025-06-05

Linda Holmquist Mengelbier is a paediatric cancer researcher who now, in parallel to her cancer effort, has started to work with the neurodegenerative disorders Huntington disease and ALS. Her focus in the cancer field has been on the embryonal pediatric solid tumors neuroblastoma and Wilms tumor. Neuroblastoma is a sympathetic nervous system tumor derived from the neural crest, whereas Wilms tumo

https://www.huntington-research.lu.se/team/linda-holmquist-mengelbier-phd - 2025-06-05

Soylu-Kucharz R, Adlesic N, Davidsson M, Björklund T, Björkqvist M and Petersén Å. bioRxiv 2023.03.04.530949; First published March 4, 2023, https://doi.org/10.1101/2023.03.04.530949 Abstract Huntington’s disease is a fatal neurodegenerative disorder caused by an expanded CAG triplet repeat in the huntingtin (HTT) gene. Previous research focused on neuropathology in the striatum and its associatio

https://www.huntington-research.lu.se/mutant-huntingtin-expression-hypothalamus-promotes-ventral-striatal-neuropathology - 2025-06-05

Dalene Skarping K, Arning L, Petersén Å, Nguyen HP and Gebre-Medhin S.Sci Rep. 2024;14(1):4300. Published 2024 Feb 21. doi:10.1038/s41598-024-54277-5AbstractDNA mismatch repair (MMR) is thought to contribute to the onset and progression of Huntington disease (HD) by promoting somatic expansion of the pathogenic CAG nucleotide repeat in the huntingtin gene (HTT). Here we have studied constitutional

https://www.huntington-research.lu.se/attenuated-huntingtin-gene-cag-nucleotide-repeat-size-individuals-lynch-syndrome - 2025-06-05

Lilja Andersson P, Juth N, Petersén Å, Graff C and Edberg AE.Lund University, Sweden.Nursing Ethics 20: 189-199 (2013)AbstractThe aim of this study was to describe the experiences of undergoing a presymptomatic genetic test for the hereditary and fatal Huntington’s disease, using a case study approach. The study was based on 18 interviews with a young woman and her husband from the decision to und

https://www.huntington-research.lu.se/ethical-aspects-undergoing-predictive-genetic-testing-huntingtons-disease - 2025-06-05