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Importance Women with adverse pregnancy outcomes have higher subsequent cardiovascular risks, but their long-term risk of atrial fibrillation (AF) and potential causality are unclear. A better understanding of such risks is needed to identify women with high risk early in life and guide interventions to prevent AF and its complications. Objective To determine long-term risks of AF associated with
A water-based sol–gel strategy driven by boron coordination enables the direct fabrication of transparent, photoactive TiO2 films under ambient conditions. Mixing ammonium oxo-lactato titanate with boric acid produces non-fluidic gels that dry into amorphous TiO2 films containing rutile-like domains.
Oligodendrocyte precursor cells (OPCs) display functional plasticity beyond myelination. Kuwata et al. explore how hypoxia shapes OPC features after ischemic stroke. Combining single-cell transcriptomics with in vivo and ex vivo models, they reveal oxygen-dependent OPC phenotypes promoting angiogenesis and remyelination, highlighting OPC versatility and potential for novel stroke cell therapies.
We propose a new class of high-rate spatially coupled LDPC (SC-LDPC) codes based on the convolutional selforthogonal codes (CSOCs) first introduced by Massey. The SCLDPC codes are constructed by treating the irregular graph corresponding to the parity-check matrix of a systematic rate R=(n-1) / n CSOC as a convolutional protograph. The protograph can then be lifted using permutation matrices to ge
Aducanumab, a human IgG1 antibody with plaque-clearing effects and modest clinical benefit, binds selectively to aggregated Aβ via the N-terminal region. Yet, the molecular details of how the antibody engages Aβ1-42 fibrils remain unresolved. Using magic-angle spinning NMR, we show that binding of aducanumab preserves the overall architecture of the Aβ1-42 fibril core while inducing significant st
Following regulatory approval of anti-amyloid beta (Aβ) therapies, a better characterization of patients receiving these treatments is needed to guide clinical management and inclusion in future trials. This Alzheimer's Association-convened workgroup proposes a terminology, treatment-related amyloid clearance (TRAC), to reflect alterations in disease pathophysiology based on biomarker evidence for
Background: Distal pancreatic resection is associated with a high frequency of postoperative complications. The aim of this study was to characterize the effect of diabetes mellitus (DM) on short-term complications after distal pancreatectomy. Methods: Patients who underwent distal pancreatectomy between 1 January 2010 and 31 December 2020 were identified from the Swedish National Pancreatic and P
Dynamic task offloading is essential for real-time robotic applications, enabling them to adapt to fluctuating computational demands and maintain efficiency under changing conditions. This paper introduces a dynamic task offloading framework that incorporates monitoring, decision making, offloading triggering, and performance monitoring to optimize resource usage by offloading real-time tasks to e
Background: Incisional hernia remains the most common complication of open abdominal surgery. The aim was to investigate whether a reinforced tension-line suture combined with standard 4: 1 small-bite closure reduces the 3-year incidence of computed tomography-detected incisional hernia in open colorectal cancer surgery. Methods: Patients aged > 18 years, scheduled for colorectal cancer resection
Background: Intraventricular hemorrhage (IVH) is a leading cause of neurodevelopmental impairment in preterm infants, driven by vascular rupture, intraventricular blood accumulation, and secondary injury. Hemolysis releases extracellular hemoglobin (Hb) into the cerebrospinal fluid (CSF), where it promotes oxidative stress, inflammation, and cytotoxicity. The endogenous Hb-scavenging protein hapto
The aim of this paper is to explore how Edmund Husserl's phenomenological account of empathy, as well as Emmanuel Levinas' critical reception of the same, could contribute with clarity to the debate over the relevance of empathy to social work ethics. I suggest that more attention should be given to the pre-reflective character of empathy, according to Husserl's account. This resonates with Levina
Recension av Mark Klambergs bok "Folkmord - Sverige och kampen om ett begrepp"
Objective: To investigate whether low daily doses of fluoridated milk, as an adjunct to oral hygiene routines with fluoridated toothpaste, can prevent caries development in enamel and dentine in adolescents. Material and methods: Adolescents (mean age 13 years) at three dental clinics in Sweden were enrolled to a randomised clinical trial (RCT) including baseline and 2-year follow-up examinations.
Rural populations in Europe face health inequalities due to a multitude of factors, including the higher prevalence of multi-morbidity, inadequate access to primary and secondary health care services, and widespread health workforce shortages. Although some challenges are also present in other contexts, the multitude and interconnectedness of these factors induce significant health inequalities. R
