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Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium
Objective: To address the need for standardization of osteoarthritis (OA) phenotypes by examining the effect of heterogeneity among symptomatic (SOA) and radiographic osteoarthritis (ROA) phenotypes. Methods: Descriptions of OA phenotypes of the 28 studies involved in the TREAT-OA consortium were collected. We investigated whether different OA definitions result in different association results by
Communicating and learning maritime safety culture - development and evaluation of a didactic design based on an interactive module
To be able to disseminate knowledge about maritime safety culture and safety management to different actors in the Swedish maritime sector, a didactic design was developed and evaluated. The didactic design includes an interactive scenario-based module and a teacher’s guide and is based on a model for experience-based learning that connects theory and practice by a cyclic approach. Students at up
Analytical dispersive construction of eta -> 3 pi amplitude: First order in isospin breaking
Because of their small electromagnetic corrections, the isospin-breaking decays n -> 3 pi seem to be good candidates for extracting isospin-breaking parameters similar to(m(d) - m(u)). This task is unfortunately complicated by large chiral corrections and the discrepancy between the experimentally measured values of the Dalitz parameters describing the energy dependence of the amplitudes of these
The Discursive Frames of Political Psychology
The aim of this article is to apply elements of contemporary social theory to the major theoretical, methodological, and ideological divisions across political psychology and to consider both the origins and the impact of a range of theories and models. In so doing, we clarify some of the complexity surrounding the discursive and cultural origins of political psychology. On the basis of this analy
Association between Sleep Disturbances and Leisure Activities in the Elderly: A Comparison between Men and Women.
It has been suggested that physical or social activity is associated with fewer sleep disturbances among elderly people. Women report more sleep disturbances than men, which could indicate a variation in activity patterns between the genders. The aim of this study was to investigate associations between sleep disturbances and leisure activities in men and women (n = 945) aged ≥60 years in a Swedis
Palaeoproterozoic porphyry Cu-Au, intrusion-hosted Au and ultramafic Cu-Ni deposits in the Fennoscandian Shield: Temporal constraints using U-Pb geochronology
The Skellefte district, northern Sweden, is known for the occurrence of 1.89 Ga Palaeoproterozoic volcanogenic massive sulphide (VMS) deposits. The deposits are hosted by the older part of a volcanosedimentary succession, which was intruded at 1.88-1.86 Ga by multiple phases of the syn-volcanic, early orogenic Jorn intrusive complex (JIC). The oldest phase of the JIC hosts different styles of mine
Continuous-wave laser annealing of Si-rich oxide: A microscopic picture of macroscopic Si-SiO2 phase separation
We report on the first observation of the macroscopic (long-range) phase separation in Si-rich oxide SiOx(x
Embryonic genome activation events in buffalo (Bubalus bubalis) preimplantation embryos
Embryonic genome activation (EGA) is the first major step towards successful initiation of preimplantation development, which culminates in the formation of implantation-competent embryos. EGA occurs at species-specific embryonic cell stages. In the present work, EGA was identified for buffalo embryos by studying the development rate of embryos in normal as well as imposed transcription block cond
Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy
Immune-regulated pathways influence multiple aspects of cancer development. In this article we demonstrate that both macrophage abundance and T-cell abundance in breast cancer represent prognostic indicators for recurrence-free and overall survival. We provide evidence that response to chemotherapy is in part regulated by these leukocytes; cytotoxic therapies induce mammary epithelial cells to pro
Assessment of myelination in hypomyelinating disorders by quantitative MRI
Curvature conditions for complex-valued harmonic morphisms
We study the curvature of manifolds which admit a complex-valued submersive harmonic morphism with either, totally geodesic fibers or that is holomorphic with respect to a complex structure which is compatible with the second fundamental form. We also give a necessary curvature condition for the existence of complex-valued harmonic morphisms with totally geodesic fibers on Einstein manifolds.
Localized deformation in intensely fissured clays studied by 2D digital image correlation
Acta Geotechnica June 2013, Volume 8, Issue 3, pp 247-263 Localized deformation in intensely fissured clays studied by 2D digital image correlation C. Vitone, G. Viggiani, F. Cotecchia, S. A. Hall … show all 4 hide Citations 368 Downloads 200 Citations 9 Comments » Download PDF (3,181 KB) » View Article Abstract This paper represents a further step in a longstanding research on the influence
Microbial communities in the subglacial waters of the Vatnajokull ice cap, Iceland
Subglacial lakes beneath the Vatnajokull ice cap in Iceland host endemic communities of microorganisms adapted to cold, dark and nutrient-poor waters, but the mechanisms by which these microbes disseminate under the ice and colonize these lakes are unknown. We present new data on this subglacial microbiome generated from samples of two subglacial lakes, a subglacial flood and a lake that was forme
The effect of parathyroidectomy on patient survival in secondary hyperparathyroidism.
Secondary hyperparathyroidism is a common condition in patients with end-stage renal disease and is associated with osteoporosis and cardiovascular disease. Despite improved medical treatment, parathyroidectomy (PTX) is still necessary for many patients on renal replacement therapy. The aim of this study was to evaluate the effect of PTX on patient survival.
Unitarising matrix element + parton shower merging
Integration of the Swedish Local Elite: The Role of Professional and Private Networks
This article uses social network data to study the integration of local elites in four Swedish municipalities. Four research questions are asked. First: How integrated are the elites? While the results modify the picture that there are two rather distinct elites in Sweden – that is, a political elite dominated by the labour movement and an economic elite dominated by business and the large busines
Genetic and environmental influence on lung function impairment in Swedish twins
Background: The understanding of the influence of smoking and sex on lung function and symptoms is important for understanding diseases such as COPD. The influence of both genes and environment on lung function, smoking behaviour and the presence of respiratory symptoms has previously been demonstrated for each of these separately. Hence, smoking can influence lung function by co-varying not only
CFD Simulation of Heat Transfer and Pressure Drop in Compact Brazed Plate Heat Exchangers
In this paper, the thermal and hydraulic characteristics of corrugated fluid channels of compact brazed plate heat exchangers (BPHE) are investigated by computational fluid dynamics (CFD) simulations using the commercial CFD software ANSYS CFX 14.0. The influence of geometry parameters of the corrugated pattern such as chevron angle and corrugation pitch on the BPHE performance is investigated on
Effectiveness of electronic fetal monitoring with additional ST analysis in vertex singleton pregnancies at > 36 weeks of gestation: an individual participant data metaanalysis
OBJECTIVE: The purpose of this study was to assess the effectiveness of electronic fetal monitoring (EFM) alone and with additional ST analysis (EFM + ST) in laboring women with a singleton term pregnancy that is in cephalic presentation in the prevention of metabolic acidosis by the application of individual patient data metaanalysis. STUDY DESIGN: We conducted an individual patient data metaanal