Emerging role of RIG-I-like receptors in antiviral innate immunity in airway structural cells
Respiratory viral infections, especially involving rhinovirus, are main triggers of exacerbations of asthma and COPD. These severe conditions are a great burden to both the individual and society and currently lack effective treatments. Hence, a clear need exists for research into the cellular and molecular mechanisms by which viral infections evoke exacerbations of airway disease in order to bett