Purpose: To investigate incidence and location of locoregional recurrence (LRR) in patients who have received postoperative locoregional radiation therapy (LRRT) for primary breast cancer. LRR-position in relation to applied radiotherapy and the primary tumor biological subtype were analyzed with the aim of evaluating current target guidelines and radiation therapy techniques in relation to tumor

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly understood, a problem that is exacerbated by the enormous genetic heterogeneity of this disease group. However, the last decade has yielded a wealth of new knowledge on degenerative pathways and their diversity. Notably, a central role of cGMP-signalling has surfaced for photoreceptor cell death triggered by

To improve the management of the European eel (Anguilla anguilla) in freshwater, it is essential to define important lotic habitats. Electrofishing data from 289 wadeable, hard-bottom sites in 69 Swedish coastal rivers and streams, originally surveyed for salmonid monitoring, were used to evaluate the effects of sampling- and habitat-related factors on eel occurrence. Probability of eel occurrence

Objective: Our main aim was to investigate the blood oxygenation level dependent (BOLD) response to monaural and binaural speech- and non-speech stimuli as measured with fMRI in subjects with single-sided deafness and in normal hearing controls. We hypothesised that the response to monaural stimulation in both normal hearing subjects and persons with single-sided deafness would vary with the compl

Knowledge bases are largely developed and utilized in academic and industrial fields, such as DBPedia, VIAF, LoC, Getty, and which are published in the Linked Data format. However, if you want to view different resources on these knowledge bases, you have to switch between different web pages from these resources. Therefore, we proposed a decentralized data hub named SinoPedia, which consists of s

We propose four different estimators that take into account the autocorrelation structure when reconciling forecasts in a temporal hierarchy. Combining forecasts from multiple temporal aggregation levels exploits information differences and mitigates model uncertainty, while reconciliation ensures a unified prediction that supports aligned decisions at different horizons. In previous studies, weig

Denne afhandling omhandler processer med lave impuls-overførsler i højenergi partikel kollisioner. Disse processer kan ikke beskrives med perturbativ QCD, og baseres derfor ofte på Regge teori, udviklet før QCD. Flere modeller er udviklet indenfor dette område, og enkelte er i denne afhandling blevet udviklet og studeret. Alle modeller er implementeret som numeriske simuleringer (en Monte Carlo evThis thesis concerns itself with low-momentum-transfer processes in high-energy particle collisions. These processes cannot be described in the framework of the fundamental theory of quantum chromodynamics (QCD), but rely on a pre-QCD approach, the Regge theory. Several models containing various degrees of complexity have been proposed within this framework, some of which have been developed and s

In order to study the effects of EG (expanded graphite) content and SiO2 nanoparticles on the specific heat and thermal conductivity of nano-SiO2/NaNO3–KNO3/EG composite heat storage materials, a series of nano-SiO2/NaNO3–KNO3/EG composites are prepared by the aqueous solution-ultrasound oscillation method. The nano-SiO2/NaNO3–KNO3 and EG with different mass fractions (5%, 10%, 15% and 20%) are us

Dermal chemical exposure is common in many professions. The filaggrin protein is important for the skin barrier and variations in the filaggrin gene (FLG) may influence the uptake of chemicals via the skin, and consequently, the degree of systemic effects. The aim of this study was to investigate, in chimney sweeps with occupational exposure to polycyclic aromatic hydrocarbons (PAH) from soot, the

Follicular fluid (FF) acts as a vehicle for paracrine signalling between somatic cells of the follicle and the oocyte. To investigate changes in the protein composition of FF during ovulation, we conducted a prospective cohort study including 25 women undergoing fertility treatment. Follicular fluid was aspirated either before or 12, 17, 32 or 36 h after induction of ovulation (five patients per t

How should a pedagogical agent in educational software be designed to support student learning? This question is complex seeing as there are many types of pedagogical agents and design features, and the effect on different student groups can vary. In this paper we explore the effects of designing a pedagogical agent’s self-efficacy in order to see what effects this has on students´ interaction wit

Sex-based differences influence incidence and outcome of infectious disease. Women have a significantly greater incidence of urinary tract infection (UTI) than men, yet, conversely, male UTI is more persistent, with greater associated morbidity. Mechanisms underlying these sex-based differences are unknown, in part due to a lack of experimental models. We optimized a model to transurethrally infec

In this thesis, I critically explore the ways in which people consume extraordinary experiences and what this can tell us about contemporary society. My findings question the idea that extraordinary experiences are an escape from the demands of everyday life. I show instead that social (especially neoliberal) discourses discipline endurance runners and shape the ways in which they understand and a