BACKGROUND: It is widely believed that autoimmune diseases affect predominantly in women, but the available evidence came from case control study with potential selection and recall bias. We aimed to examine the gender-specific incidence of autoimmune diseases by using national wide registers in Sweden.METHODS: Swedish Hospital Discharge Register and Outpatient Register were used to identify a set

There is a lack of quantitative data regarding exposure-response relationships between occupational risk factors and musculoskeletal disorders in the neck and shoulders. We explored such relationships in pooled data from a series of our cross-sectional studies. We recorded the prevalence of complaints/discomfort (Nordic Questionnaire) and diagnoses (physical examination) in 33 groups (24 female an

The world is today facing a serious problem with global warming, which is heading towards an appallingly high temperature level. The greater part of the overall climate science community agree that global warming is caused by the greenhouse effect, which depends largely on emitted CO2 emissions from the combustion of fossil fuel. The agreement at the COP 21 climate meeting in Paris (December 2015)The world is today facing a serious problem with global warming, which is heading towards an appallingly high temperature level. The greater part of the overall climate science community agree that global warming is caused by the greenhouse effect, which depends largely on emitted CO2 emissions from the combustion of fossil fuel. The agreement at the COP 21 climate meeting in Paris (December 2015)

Repetitive work and work in constrained postures are risk factors for developing musculoskeletal disorders. Low-cost, user-friendly technical methods to quantify these risks are needed. The aims were to validate inclination angles and velocities of one model of the new generation of accelerometers with integrated data loggers against a previously validated one, and to compare meaurements when usin

Scan circuit testing generally causes excessive switching activity compared to normal circuit operation. This excessive switching activity causes high peak and average power consumption. Higher peak power causes, supply voltage droop and excessive heat dissipation. This paper proposes a scan cell reordering methodology to minimize the peak power consumption during scan shift operation. The propose

The out of Africa hypothesis (OOAH) has been a mainstay in the discussion of human evolution since its presentation in the 1980's. However, recent advances in palaeontology and molecular genetics have made it possible to examine the hypothesis in a manner that was inconceivable at the time of its proposal. The palaeontological progress relates to early Homo finds in the Caucasus, Denisova finds in

Relentless CMOS scaling coupled with lower design tolerances is making ICs increasingly susceptible to wear-out related permanent faults and transient faults, necessitating on-chip fault tolerance in future chip microprocessors (CMPs). In this paper, we describe a power-efficient architecture for redundant execution on chip multiprocessors (CMPs) which when coupled with our per-core dynamic voltag

There is emerging literature emphasizing the role of inflammatory eicosanoids, including prostaglandins and leukotrienes, in cancer development. Increased expression of both the cysteinyl leukotriene receptor 1 (CysLTR1) and the enzyme responsible for the production of leukotrienes, 5-lipoxygenase (5-LOX), is associated with poor prognosis in patients with colorectal adenocarcinomas. Apc mutation

Strålbehandling är en av de vanligaste metoderna för att behandla cancer. I den mest använda formen av strålbehandling används en strålkälla utanför kroppen, så kallad extern strålterapi. Ett alternativ är att ge behandlingen med hjälp av ett läkemedel till vilket man har kopplat ett radioaktivt ämne, så kallad radionuklidterapi. Det radioaktiva läkemedlet ansamlas i tumören och ger där en intern In radionuclide therapy (RNT), radioactive pharmaceuticals are administered for therapeutic purposes. Dosimetry, i.e. the estimation of the absorbed dose to various targets, can potentially lead to a better understanding of the therapeutic effects in RNT and allow for individualization of the therapy. However, dosimetry is seldom used in RNT clinical practice, and several problems degrade the info

In the course of an ongoing screening of larger mushrooms for the occurrence of chemical mutagens, 33 out of 48 species tested exhibited a significant direct mutagenic activity in the Salmonella/microsome assay (Sterner et al., 1982). (No mutagens requiring metabolic activation were indicated.) These findings are of some concern, since mushrooms are used extensively as food in many areas, and ther

Specimens of large fungi (mushrooms) were screened for mutagenic activity by the Salmonella/microsome assay, with strains TA98, TA2637 and TA100. Out of 48 species tested, 37 exhibited a significant but for the most part weak activity. The activity observed in the presence of S9 mix was typically between 0 and 50% of that without, and in no case was the activity increased in the presence of micros

Esters of the pentacyclic sesquiterpene velutinal have been isolated from Lactarius species, and converted to the free alcohol by base-catalyzed transesterfication in EtOH/EtO-.

The Short Pulse Facility (SPF) of the MAX IV Laboratory in Lund, Sweden features the production of ultrashort, incoherent x-ray pulses. It is driven by a 3-GeV linac and comprises two 5-metre undulator modules. While the SPF is designed for spontaneous radiation, we explore alternative operation modes in which the SPF functions as a simple free-electron laser (FEL). In this article, we characteriz

We further the studies of the model-based optimization of tapered free-electron lasers presented in a recent publication [Phys. Rev. ST Accel. Beams 18, 040702 (2015)]. Departing from the ideal case, wherein the taper profile is a smooth and continuous function, we consider the more realistic case, with individual undulator segments separated by break sections. Using the simulation code GENESIS, w

In this article, we propose an arbitrage-free modelling framework for the joint dynamics of forward variance along with the underlying index, which can be seen as a combination of the two approaches proposed by Bergomi. The difference between our modelling framework and the Bergomi (2008. Smile dynamics III. Risk, October, 90–96) models is mainly the ability to compute the prices of VIX futures an

Haemophilia is a congenital disorder with bleeding episodes as its primary symptom. These episodes can result in negative outcomes including joint damage, loss of active days due to hospitalization and reduced quality of life. Effective treatment, however, can improve the outcome. Registries have been used as a valuable source of information regarding the monitoring of treatment and outcome. The t

In this article, we propose an analytical approximation for the pricing of European options for some log-normal stochastic volatility models. This approximation is a second-order Taylor series expansion of the Fourier transform with respect to the “volatility of volatility.” We give, using these formulas, a new method of variance reduction for the Monte Carlo simulation of the trajectories of the

In this article, we study the price monotonicity in the parameters of the Heston model for a contract with a convex pay-off function; in particular we consider European put options. We show that the price is increasing in the constant term in the drift of the variance process and decreasing in the coefficient of the linear term in the drift of variance process. We also show that the price is incre

OBJECTIVE: Most amputees experience referred sensations, known as a phantom hand map, on the residual forearm, where touch on specific areas is perceived as touch on the amputated hand. The aim of this study was to evaluate the sensory qualities of the phantom hand map.METHODS: In 10 traumatic forearm-amputees touch thres-holds and discriminative touch of the phantom hand map were assessed and com