Aims: The primary aim was to compare 2 years of adjuvant tamoxifen versus no systemic treatment in premenopausal patients with oestrogen receptor (ER)–positive tumours, regarding breast cancer–free interval (BCFi) and distant recurrence–free interval (D-RFi), with 30 years of follow-up and for specified intervals. Moreover, we aimed to investigate the effects of adjuvant tamoxifen on the incidence

Ovarian cancer is a heterogeneous disease and recent advances in improving patient outcome havebeen limited. It is estimated that a woman’s risk of developing ovarian cancer during her lifetime is about 1 in 70, making it a frequently occurring cancer type in women.This thesis investigated biological events in ovarian cancer, which were translated into clinically relevant observations using differ

Background When the lectinlike oxidized low-density lipoprotein (ox LDL) receptor-1 ( LOX -1), a scavenger receptor for ox LDL , binds ox LDL , processes leading to endothelial dysfunction and inflammation are promoted. We aimed to study release mechanisms of LOX -1 and how circulating levels of soluble LOX -1 ( sLOX -1) relate to plaque inflammation and future risk for ischemic stroke. Methods an

The interest in studies of diffusional processes in microemulsions has grown rapidly during the past few years. The reasons are an increased number of available techniques providing easily interpretable data and the realization that self-diffusion data give unique information on the molecular organization and structure of microemulsions. Furthermore, many current and potential applications of micr

A heterogeneous catalyst system for Suzuki and Heck coupling reactions was developed using polyoxometalates as supports for palladium. The catalyst system was synthesized in a one step process using sodium phosphotungstate and palladium acetate. We used the supported catalyst in organic media without the need for special ligands. Substantial activity was observed after several recycles. The cataly

Abstract: Businesses have increasingly engaged in various forms of cross-border transfers of activities. Much production, knowledge and work has been moved offshore from developed economies to achieve better competitiveness. However, recent research has begun to report about an opposite movement, i.e., backshoring of business activities. This research paper reports empirical survey results, explor

Background: Atrial fibrillation (AF) and dementia are predominant among the elderly; patients with AF have an increased dementia risk. We aimed to study if prescribed antihypertensive drugs and cardiovascular pharmacotherapies are associated with a lower relative risk of dementia. Methods: All included patients were ≥45 years and diagnosed with AF in primary care; 12,096 (6580 men and 5516 women)

Introduction: The risks of preterm birth are known. We investigated the perinatal and infant mortality and morbidity after iatrogenic or spontaneous onset of extremely preterm birth. Material and methods: The present study used data from the population-based EXPRESS study comprising all infants delivered before 27+0 gestational weeks in Sweden between 2004 and 2007. All fetuses alive at admission

Globalisation has led to the transformation and proliferation of urban borders. Old hierarchies and relations between centres and sub-centres and centres and peripheries are challenged, and new alliances between different places and districts are formed. How can urban design and urban design research meet the challenges of a complex and quickly transforming multi-scalar society? In this article I

Eight new species of Hieracium sect. Tridentata, namely H. antrorsum, H. quercifolium,H. stenianum, H. vestrogothicum, and H. vetlandaënse are described from the Götaland region (southern Sweden), H. grothii from Norrbotten in the Norrland region(northeast Sweden), and H. sparsifolium var. suppansum Johanss. and H. adampliatumvar. pilosius Ohlsén are raised to specific rank as H. suppansum and H.

AbstractModern medicine and health care rely on a variety of diagnostic and therapeutic equipment and methods that involve ionizing radiation. To guarantee quality and the safety of patients and staff, advanced radiation detectors and dosemeters are needed that have low energy and operate with directional independence for X-ray and γ-ray photons. Similar instruments are also of great importance fo

The purpose of this paper is to understand the relationship between the formal (governance established in law) and informal institutions (governance not established in law) that underpin the planning, operation and improvement of local and regional public transport, by using case studies of four countries: Britain (more specifically England, outside London); the Netherlands; Germany; and Sweden. T

Recent research on public transport has seen increasing focus on issues like coordination, collaboration and steering in complex governance settings. One of the themes in this field of research is related to partnership approaches, as one way of stimulating functioning collaboration between formally independent private and public organisations. The aim of this paper is to explore the role and func

This paper is about collaboration in public transport governance. Drawing upon the emerging literature that views collaboration through the lens of networks, we explore why and how regional public transport authorities collaborate with both municipalities and public transport operators in the planning of public transport. We also explore the advantages and disadvantages of such collaborations. Bas