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Bacteria: Building the Future from Thin Air Imagine what would happen if you could make nylon and other things that are needed to create everything from clothes to plastic containers with the use of microorganisms. It may seem far-fetched, but it’s getting closer to becoming reality. All you would need to get started is to help a few species of very special bacteria get even better at something t

Background: There has been an increasing number of single-centre studies describing the long-term outcomes of patients with Hirschsprung disease. This study aimed to systematically review the literature on long-term bowel, urological, and sexual functional outcomes, fertility and quality of life in adults with Hirschsprung disease. Methods: A PROSPERO-registered systematic review of the English li

Context. AU Mic is a very active M dwarf star with an edge-on debris disk and two known transiting sub-Neptunes with a possible third planetary companion. The two transiting planets exhibit significant transit-timing variations (TTVs) that are caused by the gravi tational interaction between the bodies in the system. Aims. Using photometrical observations taken with the CHaracterizing ExOPlanet Sa

Purpose The EPHOR-NIGHT cohort was established to investigate how night shift work influences biological pathways and chronic disease risk using a comprehensive working-life exposome approach, focusing on cardiometabolic, mental health, cognitive and biological ageing outcomes. Participant The cohort includes 937 workers aged 20–65 years (88%female), primarily from the healthcare sector (96%) in S

Background: Explicit weight bias is known as negative attitudes and beliefs toward individuals due to their weight status and can be perpetuated through misconceptions about the causes of obesity. Individuals may also experience weight bias internalization (WBI) when they internalize negative weight-related attitudes and self-stigmatize. There is a paucity of research on the beliefs about the caus

Introduction: Despite being implicated in a wide spectrum of community- and healthcare-acquired infections, anaerobes have not yet been incorporated into systematic surveillance programs in Europe. Methods: We conducted a multicentre retrospective observational study analysing all anaerobic strains isolated from blood cultures in 44 European Hospital Centres over a 4-y period (2020–2023). Diagnost

Background: Metformin is one of the most used drugs worldwide. Given the increasing use of proteomics in trials, bioresources, and clinics, it is crucial to understand the influence of metformin on the levels of the circulating proteome. Methods: We analysed a combined longitudinal proteomics dataset from the IMPOCT, RAMP and S3WP-T2D clinical trials in 98 participants before and after metformin e

Atrial fibrillation (AF) is increasingly diagnosed early, close to its first occurrence due to: (i) increased public awareness with self-screening; (ii) health care initiatives including population screening and opportunistic case finding; and (iii) increased use and surveillance of implantable cardiac devices. At its onset, AF is often low burden, and cardiovascular co-morbidities may be absent o

In multiple-planet systems, gravitational interactions of exoplanets could lead to transit timing variations (TTVs), whose amplitude becomes significantly enhanced when planets are in or near mean-motion resonances (MMRs), making them more easily detectable. In cases where both TTVs and radial velocity (RV) measurements are available, combined analysis can break degeneracies and provide robust pla

Integrating multi-modal patient data to support personalized medicine has gained a lot of interest across different health domains over the past decade. Addressing this challenge requires the development and implementation of an informed, evidence-based AI-driven decision-support system continuously maintained and updated to align with the latest clinical guidelines. A key challenge to ensure its

Groundwater stored in alluvial fan aquifers represents a key water resource in semi-arid mountainous regions, yet groundwater recharge mechanisms and flow dynamics remain poorly understood, particularly in data-scarce regions experiencing increasing water demand and anthropogenic pressure. This study investigates groundwater recharge processes and flow patterns in three adjacent watersheds of the

To find the optimal by-pass road alignment in the Tlokweng Planning Area in Botswana, a multi-criteria spatial-based model is developed using the GIS-MCE approach. In respect to the environmental impact assessment (EIA) approach, in this research a set of criteria is classified under 3 themes – economic, environmental and social. To determine the criterion and theme weights and perform their aggre

The authors of this policy brief are contributors to the research project Infrastructuring Libraries in Transformation (ILIT). ILIT’s objective is to examine public libraries’ role in this era beset by social challenges such as segregation, discrimination, austerity measures, and unemployment. ILIT began conducting research in three urban communities in 2022: Malmö, Sweden; Rotterdam, the Netherla

There is an increased need for floors that can accommodate different type of sensitive equipment [1]. Further, it is recommended to design these floors as high frequency floors (HFF) to be able to meet the stringent vibration criteria [1]. This work used experimental measurements and numerical simulations to gain a deeper knowledge about the measurement, prediction and evaluation of vibrations in