Intratracheal instillation of Sephadex beads induced a long-lasting inflammation in the rat lung as seen by an increase in lung weights. Repeated instillation enhanced this reaction and increased lung endothelin-1 content 3.5 times. Budesonide given s.c. abolished these effects and even reduced basal endothelin-1 content by 72%. The tissue content of the sensory neuropeptide neurokinin A were unaf

Submerged sea grasses and stoneworts growing in the immediate nearshore of the Baltic Sea are sensitive indicators of sea level. The alternating changes in concentrations of sea grass and stonewort macrofossils, obtained from an ancient lagoon of the Baltic Sea, are ascribed to middle Holocene sea-level fluctuations along the southeastern Swedish coast. Abundances of stonewort and sea grass macrof

Data from Z decays in DELPHI have been searched for --> D*+ l(-) (ν) over bar (l) with the D*+ decaying to D(0)pi(+) and D-0 --> K(-)pi(+), K(-)pi(+)pi(+)pi(-) or K- pi(+)(pi(0)). These events are used to measure the CKM matrix element V-cb and the form factor slope, rho(A1)(2): F-D*(1) V-cb = 0.0392 +/- 0.0018 +/- 0.0023; rho(A1)(2) = 1.32 +/- 0.15 +/- 0.33 corresponding to a branching fraction:

PURPOSE: To clinically characterize a Swedish family with autosomal dominant retinitis pigmentosa due to a mutation, Arg-172-Trp, in the peripherin/RDS gene. METHODS: Full clinical evaluation including kinetic visual field testing, measurement of dark-adaptation threshold, and full-field electroretinography in seven patients with autosomal dominant retinitis pigmentosa and three healthy family mem

BACKGROUND AND PURPOSE: Shoulder pain is a well-known complication after stroke, but data on prevalence, predictors, and outcome in unselected stroke populations are limited.METHODS: During a 1-year period, 416 first-ever stroke patients were included in the population-based Lund Stroke Register. After 4 months, 327 patients were followed up and 1 year later, the surviving 305 patients were follow

An integrated view on the possible effects of global climate change is provided while taking into account that not only the rising average temperature is likely to impact natural populations but also that increased variation around the mean and higher frequency of extreme events will be important. We propose that complex genetic effects in concert with demographic patterns may affect how focal pop

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An analysis of siderophores produced by Magnaporthe grisea revealed the presence of one intracellular storage siderophore, ferricrocin, and four coprogen derivatives secreted into the medium under iron depletion. Structural analysis showed that the compounds are coprogen, coprogen B, 2-N-methylcoprogen and 2-N-methylcoprogen B. Siderophore production under low and high iron conditions was quantifi

Abstract is not available

In consecutive series of 326 laryngeal cancer patients, of 29 (9%) with stage T3N0 glottic carcinomas, 23 achieved complete local remission after curative radiotherapy and form the basis of the present investigation. Flow cytometry determinations of DNA-ploidy status and the S-phase fraction, and a "histopathological malignancy grading system" were evaluated as possible patient- and/or tumor-relat

This thesis summarizes experimental work in which the powerful Ti:sapphire lasers at the High Power Laser Facility at the Lund Laser Centre have been employed to investigate laser-produced X-rays and relativistic channelling. These lasers produce short pulses, of the order of 50 fs, with energies ranging from 1 mJ to 1 J. Thus, the peak powers reach several terawatts and with the most powerful las

Swedish universities and government authorities are increasingly making their publications electronically available on the World Wide Web, either on web sites or in local systems, so called institutional repositories. Standardisation of metadata is a way of increasing access to these publications. Tools and workflows are also being developed to secure long term preservation and access. On 18 Octob

Abstract is not available

A role for regulatory lymphocytes has been demonstrated in the pathogenesis of type I diabetes in the NOD mouse but the nature of these cells is debated. CD1d-restricted NKT lymphocytes have been implicated in this process. Previous reports of reduced diabetes incidence in NOD mice in which the numbers of NKT cells are artificially increased have been attributed to the enhanced production of IL-4