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1. Extracellular adenosine triphosphate (ATP) is mitogenic for vascular smooth muscle cells (VSMC) and stimulates several events that are important for cell proliferation: DNA synthesis, protein synthesis, increase of cell number, immediate early genes, cell-cycle progression, and tyrosine phosphorylation. 2. Receptor characterization indicates mitogenic effects of both P2U and P2Y receptors. The

Analys av hur man i Hollywood brukat historia före och efter terrordåden elfte september 2001.

We consider the semi-linear elliptic equation Delta u + f (x, u) + g (vertical bar x vertical bar)x center dot del u = 0, in some exterior region of R-n, n >= 3. It is shown that if f depends radially on its first argument and is nonincreasing in its second, boundary conditions force the unique solution to be radial. Under different conditions, we prove the existence of a positive radial asymptoti

The interruption in deposition during the K/T transition in the Parnassus-Ghiona Zone caused the formation of hardgrounds and intraformational conglomerates in the central parts. During the later part of the early Paleocene to the middle or early part of the late Paleocene a shallow sea covered central Parnassus; stromatolites formed in broad valleys and phosphatic calcarenitic accumulations in sm

We report the temperature dependence of the Au-assisted growth of InAs nanowires in MOVPE. Extensive studies of the growth of such nanowires have attributed growth to the so-called vapor-liquid-solid (VLS) mechanism, with a liquid Au-In alloy particle. We assert here that growth is instead assisted by a solid particle and does not occur at all when the particle is a liquid. Thus the temperature ra

The tumor oxygenation status associates with aggressive behavior. Oxygen shortage, hypoxia, is a major driving force behind tumor vascularization, and hypoxia enhances mutational rate, metastatic spread, and resistance to radiation and chemotherapy. We recently discovered that hypoxia promotes dedifferentiation of neuroblastoma and breast carcinoma cells and development of stem cell-like features.

Popular Abstract in Swedish Traditionellt har olika aspekter av ett ekosystem studerats var för sig inom olika ekologiska discipliner såsom växtfysiologi, forskning om hur organismer interagerar med varandra och forskning om hur ekosystem som helhet beter sig. Denna avhandling innehåller exempel på att simulationsmodeller gör det möjligt att undersöka hur de olika processerna samverkar för att forPlant physiology, population dynamics and the structure and functioning of ecosystems are closely interrelated. However, these processes are often investigated independently within different subdisciplines of ecology. Mechanistic models of ecosystem structure and functioning combine representations of processes operating at a range of scales and levels of organisation, providing a tool for the des

Secretory lysosomes of natural killer (NK) cells combine storage, regulated secretion and lysosomal activity. We asked whether one could target exogenous proteins to the secretory lysosomes of NK-cells for final delivery into a tumor site upon degranulation. cDNAs for both soluble and transmembrane (tm) proteins were expressed in the human YT-Indy NK-cell line. Targeting of a soluble TNF receptor

An enzyme has been isolated from human liver by DEAE-cellulose chromatography and has been shown by competitive substrate inhibition to be capable of hydrolysing synthetic beta-D-galactosides, beta-D-glucosides, beta-D-fucosides, beta-D-xylosides, and alpha-L-arabinosides. Another form of alpha-L-arabinosidase activity elutes with the major beta-D-galactosidase component on DEAE-chromatography, bu

In this prospective study, the overall treatment and outcome of patients that underwent major lower limb amputation in a defined population is described. The study was performed over a five year period in the Health Care District of North-East Skåne, Sweden. Some 190 patients, permanent inhabitants of the Health Care District, underwent major lower limb amputation. Sixteen (16) of these patients h

Freshwater dinoflagellates may form dense blooms during winter in ice-covered lakes. Unlike their marine counterparts, freshwater dinoflagellates are rarely considered to be potential toxin producers. Here we tested whether the winter species Peridinium aciculiferum produces a toxin(s) and investigated the potential adaptive function of that toxin, i.e., predator defense or inhibition of competito

We present experimental results and theoretical calculations of the vertical electron transport through a laterally constricted resonant tunneling transistor. Current-voltage measurements at 4.2 K show numerous current peaks that exhibit a complex dependence on the applied gate voltage. A scattering-matrix approach combined with the Landauer formalism was used to perform quantum mechanical calcula

In this paper, we present a detailed experimental study of turbulence chemistry interactions in the "DLR_B" turbulent jet diffusion flame. The flame operates on mixtures of CH4, H-2, and N-2 in the fuel stream at Re = 22,800 and is a target flame within the TNF workshop. Extinction and re-ignition events can be tracked in real time and related to the underlying flow field phenomena and temperature

Intrastriatal transplantation of embryonic dopaminergic neurons is currently explored as a restorative cell therapy for Parkinson disease (PD). Clinical results have varied, probably due to differences in transplantation methodology and patient selection. In this review, we assess clinical trials and autopsy findings in grafted PD patients and suggest that a minimum number of surviving dopaminergi

"Tidskrift för politisk filosofi" nr 2/2003 innehåller en kritisk granskning av Larry Temkins inflytelserika bok "Inequality" från 1993. Författarna, Ragnar Francén, Jonas Gren och Niklas Juth, underkastar Temkins komplexa, flerdimensionella form av egalitarism en noggrann undersökning. Deras kritiska synpunkter är väl värda läsarens uppmärksamhet.

Acute airway obstruction during oral intake is a relatively common event that may be fetal if not relieved immediately. Deglutition was studied in 75 individuals who had experienced a near-fatal choking episode (NFCE) or sudden inability to breathe during food intake that was promptly relieved by means of a Heimlich maneuver, suctioning, or intubation. Videofluoroscopy supplemented by static imagi