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l-DOPA-induced dyskinesia (LID) is a prevalent complication of dopamine replacement therapy in Parkinson’s disease. In addition to its clinical importance, LID represents a paradigm to unravel how altered signaling downstream of dopamine receptors can disrupt mechanisms of synaptic plasticity and motor information processing in the cortico-basal ganglia network. This chapter focuses on experimenta
The aim of this study was to perform histopathological reassessment of primary resections of locally advanced colon cancer (CC) within a randomized controlled trial, with specific focus on surgical margins and synchronous locoregional peritoneal metastases (SL-PM), and to provide learning points for both surgeons and pathologists. All histopathological slides of patients with c/pT4N0-2M0 or perfor
Modified ZYMO DNA/RNA miniprep extraction protocol written in a user friendly way to reduce in-process-decisions and process time. Sample type is organic soil, peat, from a degraded rich fenThis protocol includes two modifications to tackle clogged filters. Samples were centrifuged for 45 seconds instead of 30 seconds in first pass through filters as 100 ul to 200 ul sample remained trapped above
Boreal forests emit terpenoid biogenic volatile organic compounds (BVOCs) that significantly affect atmospheric chemistry. Our understanding of the variation of BVOC species emitted from boreal ecosystems is based on relatively few datasets, especially at the ecosystem-level. We conducted measurements to obtain BVOC flux observations above the boreal forest at the ICOS (Integrated Carbon Observati
Bryophytes constitute a diverse plant group with important roles in ecosystem functioning, in particular in arctic and subarctic environments. As they are physiologically strongly dependent on climatic conditions bryophytes could serve as indicators of ongoing climatic change. Their spores are generally dispersed by wind, and because of contrasting phenologies among species, the composition of the
BackgroundSome patients scheduled for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) only undergo explorative laparotomy (open/close procedure) due to extensive tumor spread or challenges in achieving complete cytoreduction (CC0). This study aimed to evaluate the surgical outcomes and overall survival in patients with peritoneal surface malignancy (PSM) who only
We recently published an article that demonstrates how eDNA can reveal shifts in the annual timing of wind-carried dispersal agents (spores) of mosses and liverworts.
This article assesses the determinants of intragenerational social mobility across occupational trajectories in Southern Europe, focusing on Catalonia (1880s–1950s). Using a novel longitudinal database of individuals born 1870–1909 in the Baix Llobregat area, we examine sibling correlations in occupational status as a proxy for family socioeconomic resemblance and trace career progression across e
A secondary objective of Bryomolecules is to apply methods developed in the project for what is known as ex situ preservation, that is, maintaining collections of endangered species in laboratory cultures. It is undoubtedly always best to preserve the species in their natural environment, but sometimes this is not enough. Lab cultures could potentially be used to replace populations that have gone
The scene floor of the forest theatre consists of a green mat of small plants. For most people it is quite anonymous and un-noticed, but several hundreds of species could thrive in this environment. In my research, I try to understand aspects of this hidden world of mosses and liverworts, including their relations to other plants and animals.
Viruses that infect single-celled algae strongly regulate microalgae growth and community composition through cell lysis, enable nutrient recycling in marine ecosystems, and offer valuable insights into early stages of viral evolution. One major group, the Bacilladnaviridae family of single-stranded DNA viruses, infects diatoms in marine environments. Here, we present the capsid structure of Ch
The biogeophysical forcing resulting from the change in land-surface properties (such as albedo) is of particular interest as it can increase, decrease, or offset the biogeochemical forcing resulting from the changes in atmospheric greenhouse gas concentrations due to deforestation, forest management, or reforestation/afforestation (i.e., land-use/land-cover change, LULCC). Moreover, the biogeophy
In situ geologic context mapping based on rover and helicopter observations provides documentation of a nearly continuous record of geology and exposed surface structure over a 120 m-wide corridor along the traverse of the Mars 2020/Perseverance rover. The results record the geologic context of Mars 2020 campaign sites and sample sites, including the local extent of bedrock outcrops, stratigraphy,
dolescents with an immigrant background have poorer educational performance than their native counterparts, which may partly be explained by the quality of their neighbourhood area upon immigration to Sweden. An important part of neighbourhood quality is neighbourhood socioeconomic status (NSES). This study examines the impact of initial NSES on subsequent school grades in refugees by using a natuAdolescents with an immigrant background have poorer educationalperformance than their native counterparts, which may partly be explainedby the quality of their neighbourhood area upon immigration to Sweden. Animportant part of neighbourhood quality is neighbourhood socioeconomicstatus (NSES). This study examines the impact of initial NSES on subsequentschool grades in refugees by using a natural
Natural history collections hold immense global significance – not only as historical archives but also as precious resources for novel scientific discoveries. These collections, housed in museums and institutions worldwide, are (or should be) accessible and open for study. In this paper, we provide a brief history of the fossil collections at Lund University, Sweden, tracing their origins, key hi
Modified ZYMO DNA/RNA miniprep extraction protocol written in a user friendly way to reduce in-process-decisions and process time. Sample type is organic soil, peat, from a degraded rich fenThis protocol includes modifications to tackle clogged filters. Samples were centrifuged for 45 seconds instead of 30 seconds in first pass through filters as 100 ul to 200 ul sample remained trapped above filt
