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While the associations of mid-life cardiovascular risk factors with late-life white matter lesions (WMH) and cognitive decline have been established, the role of cerebral haemodynamics is unclear. We investigated the relation of late-life (69–71 years) arterial spin labelling (ASL) MRI-derived cerebral blood flow (CBF) with life-course cardiovascular risk factors (36–71 years) and late-life white

Aim: Sweden has historically provided a fruitful arena for research in clinical medicine. We here share 40 years of experience of collaboration in the Swedish hepatology research group (SWEHEP) (https://www.swehep.se). Methods: We describe the way the Swedish hepatology pioneers started the group and how the network continuously developed over the years. Successful projects such as thorough studie

While there is ample evidence supporting genetic control of migratory behaviour in short-lived passerines, long-lived social species have been assumed to rely solely on cultural inheritance of migratory routes. Evidence from experimental studies supporting this idea is scarce. We tested whether the moult migration in taiga bean geese Anser fabalis has an inherited component or whether the birds ne

Objective: The objectives were to determine the prevalence of meeting criteria for symptoms suggestive of early osteoarthritis (OA) after anterior cruciate ligament reconstruction (ACLR) and to characterize the longitudinal changes in these symptoms during the first two years post-ACLR. Methods: We analyzed data from 10,231 patients aged 14 to 40 years in the New Zealand ACL Registry who completed

In the 1960s, people across the West started imagining that they were in a societal transition. Crucially, in these future-oriented discussions, social class was often transformed into educational attainment as the main dividing line. These future studies garnered attention across the political spectrum, including the Swedish Conservative Party. This article aims to investigate the Conservative Pa

Titanium alloys are difficult-to-machine materials given their high strength, the high temperatures generated, and the naturally short contact length that combined result in rapid tool wear. Different machining strategies can be employed to cope with the low machinability. This study investigates the machining performance using different cooling and lubrication methods during down face milling of

Assessing short channel effects (SCEs) is crucial in the high-frequency optimization of downscaled field-effect transistors (FETs) such as GaN high electron mobility transistors (HEMTs). Drain-induced barrier lowering (DIBL) is commonly used for quantifying the ability of the gate to modulate the drain–source current at high drain voltages. DIBL is traditionally extracted from the relative shift o

The Andes, the world’s longest mountain system (8500 km), harbour important headwater systems that constitute crucial water resources for South America. Their complex topography significantly influences climate and hydrology. The Andes have a wide diversity of aquatic environments, with >5000 lakes (>0.1 km2, permanent and excluding constructed reservoirs) with different morphometry, including the

Sustainability of future aviation platforms is heavily dependent on the lower emission capabilities of aeroengines which can be addressed by means of utilizing jet fuels of biological origin. Thus, an extensive experimental and numerical investigation campaign utilizing the Triple Annular Research Swirler (TARS) burner is started to understand the thermochemical properties and combustion character

Introduction: Supervised physical exercise has been shown to benefit patients with heart failure with preserved/mildly reduced ejection fraction (HFpEF/HfmrEF) by improving symptoms and diastolic function. This study aimed to investigate the correlation between unsupervised daily physical activity and changes in daily pulmonary artery pressure (PAP) in patients with stable NYHA class III heart fai

Objectives: Discrimination and prejudice are prevalent in workplaces worldwide, but there are few empirically validated interventions for combating racial bias in organizational settings. This study aims to evaluate an intervention consisting of experiential exercises derived from Acceptance and Commitment Therapy (ACT) and Compassion-Focused Therapy (CFT). The objective is to address psychologica

Aim: To analyse the association between bone turnover markers and bone mass in children and young adults. Methods: This descriptive study followed 132 children (68 boys/64 girls) from Malmö, Sweden, as controls in a school-based intervention study (2000–2017). Height, weight, Tanner stage and bone mass were measured annually from ages 8 to 15 years, with follow-ups at 19 and 23 years of age. Serum

Elevated plasma levels of oxidized low-density lipoprotein (oxLDL) are a risk factor and key component that accelerates and worsens cardiovascular disease fueling inflammation, plaque buildup and vascular damage. OxLDL can elicit its detrimental action via lectin-like oxLDL receptor 1 (LOX-1). In this study, we determined whether oxLDL, via LOX-1, alters aortic vascular reactivity and determined i

Imaging the strain in nanoscale heterostructures is challenging since it requires a combination of high strain sensitivity and spatial resolution. Here, we show that three-dimensional (3D) Bragg coherent diffraction imaging (BCDI) can be used to image the strain in a single InP segment within an axially heterostructured GaInP-InP nanowire. We use a 350 nm-diameter X-ray beam, which is smaller than

This paper discusses a presumed medieval tower in Blekinge. The tower is situated close to a harbour in an inlet of the Baltic just east of modern day Ronnebyhamn. Archaeological investigations in 2021 and 2023 have however firmly dated the tower to the 17th century, making it the first Scandinavian example of a tower-house from the Early Modern era. The tower originally had at least three floor-l

Background: Although glomerular diseases are the third most frequent cause of end-stage kidney disease worldwide, little is known about their long-term outcomes. Methods: In patients with chronic kidney disease (CKD) stage 3–5 enrolled in the Swedish Renal Registry, we compared risks of hospitalization, kidney replacement therapy (KRT), major cardiovascular events (MACE), and death of the four mos

The Baltic Sea has a generally low biodiversity, and several species are declining due to high anthropogenic pressure. One example is the Baltic Sea cod (Gadus morhua, L.), the cod has decreased since the 1980s in both biomass and abundance. One potential solution to increase the cod population is to improve settling ground and provide shelter for juveniles in artificial reefs. The Hanö Cod Reef p

Stimuli-responsive polymers stand out for their ability to respond to small environmental changes. One of the most representative thermo-sensitive materials is poly(N-isopropyl acrylamide) (PNIPAm), which presents reversible phase transitions close to the human body temperature. However, previous studies observed that the copolymerization of NIPAm with small quantities of different monomers like a

The mitochondrial protein NAD(P) + transhydrogenase (NNT) has been implicated in the metabolic derangements observed in obesity. Mice with the C57BL/6J genetic background bear a spontaneous mutation in the Nnt gene and are known to exhibit increased susceptibility to diet-induced metabolic disorders. Most of the studies on NNT in the context of diet-induced obesity have compared C57BL/6J mice with

Hur kan svenska kommuner navigera i en alltmer komplex och osäker framtid? Med intervjuer och dokumentstudier från elva kommuner blottlägger en ny studie de strategiska utmaningarna och belyser vikten av balans mellan kapacitet och öppenhet för nya lösningar. Fyra kommuntyper träder fram.