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Peatlands have become a silver bullet in climate mitigation policy globally. Restoring and rewetting agricultural peatlands is key for meeting reduction targets within the agricultural sector. But unlike other sectors, change rests on the decisions of individual farmers. In Denmark, a political aim towards restoring 100.000 hectares of agricultural peatlands by 2030 is challenged by uncertainty, d

INTRODUCTION: Low birth weight is an important measure of the health of pregnant women and newborns. We investigated the prevalence of low birth weights in India over nearly three decades to assess trends and convergence across states.METHODS: Data came from five waves of the National Family Health Survey (1992-93 to 2019-21). The prevalence of low birth weight was estimated. To explore the sensit

Metabolically engineered baker’s yeast can be used to produce chiral amines through whole-cell bioconversion of prochiral ketones. This study investigates the modulation of the alanine-pyruvate metabolic node to enhance reductive amination, using the stereoselective conversion of benzylacetone to (S)-1-methyl-3-phenylpropylamine (MPPA) as a model reaction. Chromosomal integration of multiple copie

AIMS: Diet is a determinant of cardiovascular diseases (CVD) with coronary disease as predominant cause of pre-mature death. To analyse how diet was associated with coronary atherosclerosis, including plaque features.METHODS AND RESULTS: The cross-sectional population-based study using data from the Swedish CArdioPulmonary BioImage Study (SCAPIS) included 24 079 adults aged 50-64 years, recruited

Background We seek to clarify how changes in the prevalence of drug use disorder (DUD) in Sweden in the 1950-1990 birth cohort impact the aggregation and co-aggregation in siblings of DUD and alcohol use disorder (AUD). Methods We examined risk for DUD and AUD in siblings of 102,624 DUD cases and matched control probands and 123,837 AUD case and matched control probands identified using Swedish re

Ammonia (NH3) emerges as a promising carbon-free fuel, necessitating an understanding of its fundamental combustion properties, particularly the laminar burning velocity (SL), at very high unburnt temperatures (Tu). Despite this need, a consensus on the relationship between SL and Tu across a broad temperature range has not yet been established. This study investigated the SL vs. Tu relationship f

Parkinson's disease (PD) is characterized by dopaminergic neurodegeneration, α-Synuclein (α-Syn) pathology, and inflammation. Microglia in the substantia nigra pars compacta (SNpc) upregulate major histocompatibility complex class II (MHCII), and variants in genes encoding MHCII affect PD risk. Additionally, elevated TNF levels and α-Syn-reactive T cells in circulation suggest a strong link betwee

Background: Hexavalent chromium (Cr(VI)) is a lung cancer carcinogen. However, the genotoxic and mutagenic effects of Cr(VI) in humans at low-to-moderate occupational exposure levels are unknown. This study aims to investigate the relationship between occupational exposure to Cr(VI) and the presence of oxidative damage, genetic and epigenetic alterations. Methods: We included 113 Cr(VI) exposed wo

Context Developing compilers and static analysis tools (“language tools”) is a difficult and time-consuming task. We have previously presented property probes, a technique to help the language tool developer build understanding of their tool. A probe presents a live view into the internals of the compiler, enabling the developer to see all the intermediate steps of a compilation or analysis rather

Many software language tools use declarative domain-specific languages (DDSLs) to implement parts of their functionality, such as context-free grammars for parsing or inference rules for type analysis. For interoperability and ease of use, DDSLs often rely on embedded general-purpose language (GPL) code fragments, as in the semantic actions of parser specifications, but require that these GPL frag

Sundarban mangrove is the largest continuous mangrove forest in the world and is the habitat of an incredible amount of biodiversity. Biodiversity loss and degradation of this highly ecologically productive mangrove forest due to climate change will have a tremendous impact on the livelihood of the people living in the deltaic region. The present study was aimed to find out the dynamics of change

This study investigates new and alternative communication models of sustainable fashion within Instagram thrift stores in India using digital affordances of social media platforms. Drawing from interdisciplinary areas of fashion, media, and sustainability, we explore how social media platforms, such as Instagram, enable sustainable fashion systems of creation and consumption in distinct socio-ecol

Background: Glucose-dependent insulinotropic polypeptide (GIP) was the first incretin identified and plays an essential role in the maintenance of glucose tolerance in healthy humans. Until recently GIP had not been developed as a therapeutic and thus has been overshadowed by the other incretin, glucagon-like peptide 1 (GLP-1), which is the basis for several successful drugs to treat diabetes and

This article explores two works by Swedish artists Emanuel Cederqvist and Henrik Andersson that relate to the vast alpine areas of Norrland in the far north of Sweden. In both works, the artists relate their experiences of the area as it exists today as well as the layers of its history through both archival material and their own photographs. More specifically, both artists use material that show

Organ function depends on the three-dimensional integrity of the extracellular matrix (ECM). The structure resulting from the location and association of ECM components is a central regulator of cell behavior, but a dearth of matrix-specific analysis keeps it unresolved. Here, we deploy a high-resolution, 3D ECM mapping method and design a machine-learning powered pipeline to detect and characteri

The tyrosine residue in amyloid-β (Aβ) is susceptible to attack by various reactive nitrogen intermediates, leading to the formation of 3-nitrotyrosine (3-NT), a post-translational modification associated with the pathophysiology of Alzheimer's disease (AD). Although considered a “dead-end” product, emerging evidence suggests that 3-NT can be reduced to 3-aminotyrosine (3-AT) in vivo. This study a

In 2020, a case report described autologous transplantation of iPSC-derived dopamine (DA) neurons in a Parkinson's disease (PD) patient.1 The team now follows up with the pre-clinical safety and efficacy data of autologous iPSC-derived DA neurons, forming the basis for regulatory approval of a phase 1 clinical trial involving 8 patients.2