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Syftet med nuvarande arbetet är att genomföra en klinisk fallstudie som utvärderar begreppet Dynamisk-ElectroEnhanced Chemotherapy ™ (D-EECT). Tio patienter med plavocellkarcinom, åtta med bröstcancer och fem patienter med var och en som presenterade en annan typ av tumör, infördes i försöken initierade av fem olika cancercentra. Alla patienter fick Bleomycin och 2-3 behandlingstider med IQWave ™ The aim of the present work is to perform a clinical case study evaluating the concept of Dynamic-ElectroEnhanced Chemotherapy™ (D-EECT). Ten patients with squamous cell carcinoma, eight with breast cancer and five patients with each presenting a different type of tumour, were entered in the trials initiated by five different cancer centres. All the patients were given Bleomycin and 2 to 3 treatme

Den fackliga organisationsgradens utveckling i Sverige redovisas till och med 2018 (+ uppdatering t o m 2019), det vill säga andelen löntagare som är medlemmar i ett fackförbund. Denna rapport innehåller (1) en grundlig beskrivning av utvecklingen när det gäller organisationsgrad (på både fack- och arbetsgivarsidan), kollektivavtalstäckning och andra förändringar av partsmodellen; (2) en analys av

In this work, we have determined the energy of the S1 state of the carotenoid spheroidene. The energy of this state is 13,400 ± 90 cm-1 at both 293 K and 186 K, showing that there is no temperature-induced shift of the S1 level. A discrepancy of about 800 cm-1 between the S1 energy determined here and that obtained from previous fluorescence and resonance Raman measurements is explained in terms o

A search for Higgs boson pair production in the bb¯ WW * decay mode is performed in the bb¯ ℓνqq final state using 36.1 fb −1 of proton-proton collision data at a centre-of-mass energy of 13 TeV recorded with the ATLAS detector at the Large Hadron Collider. No evidence of events beyond the background expectation is found. Upper limits on the non-resonant pp → HH production cross section of 10 pb a

Inflammatory myofibroblastic tumour (IMT) is a soft tissue tumour primarily affecting children and young adults. Approximately 50% of IMTs have gene fusions involving the receptor tyrosine kinase (RTK)-encoding ALK gene, providing a molecular rationale for treating IMT patients with unresectable tumours with tyrosine kinase inhibitors (TKI). However, a subset of IMT instead displays fusions affect

Chemical abundances for 15 elements (C, N, O, Na, Mg, Al, Si, K, Ca, Ti, V, Cr, Mn, Fe, and Ni) are presented for 83 stellar members of the 4 Gyr old solar-metallicity open cluster M67. The sample contains stars spanning a wide range of evolutionary phases, from G dwarfs to red clump stars. The abundances were derived from near-IR (λ1.5-1.7

We present a protocol for performing gas spectroscopy using infrared degenerated four-wave mixing (IR-DFWM), for the quantitative detection of gas species in the ppm-to-single-percent range. The main purpose of the method is the spatially resolved detection of low-concentration species, which have no transitions in the visible or near-IR spectral range that could be used for detection. IR-DFWM is

We map the trends of elemental abundance ratios across the Galactic disk, spanning R = 3-15 kpc and midplane distance |Z| = 0-2 kpc, for 15 elements in a sample of 20,485 stars measured by the SDSS/APOGEE survey (O, Na, Mg, Al, Si, P, S, K, Ca, V, Cr, Mn, Fe, Co, Ni). Adopting Mg rather than Fe as our reference element, and separating stars into two populations based on [Fe/Mg], we find that the m

Anaplastic thyroid cancer (ATC) is a rare and extremely malignant tumor with no available cure. The genetic landscape of this malignancy has not yet been fully explored. In this study, we performed whole exome sequencing and the RNA-sequencing of fourteen cases of ATC to delineate copy number changes, fusion gene events, and somatic mutations. A high frequency of genomic amplifications was seen, i

Sverige kan bli ledande i en radikal omställning av framtidens matproduktion. Genom forskning och utveckling av perenna livsmedelsgrödor kan vi aktivt främja en perenn revolution i jordbruket. Perenna grödor återkommer år efter år utan att behöva sås på nytt, skriver en rad forskare.

The complex evolution of chloroplasts in microalgae has resulted in highly diverse pigment profiles. Freshwater raphidophytes, for example, display a very different pigment composition to marine raphidophytes. To investigate potential differences in the evolutionary origin of chloroplasts in these two groups of raphidophytes, the plastid genomes of the freshwater species Gonyostomum semen and Vacu

There has been recent increased interest in premixed flames and in particular for use in gas turbines for power generation. This is a development that follows from increasing demands for high efficiency and low emissions of NOx, which can be achieved by using premixed flames and lean pre-heated mixtures, often close to the lean flammability limit. In combination with high levels of turbulence, whi

Oxidative stress plays a role in the onset and progression of a number of diseases, such as Alzheimer’s disease, diabetes and cancer, as well as ageing. Oxidative stress is caused by an increased production of reactive oxygen species and reduced antioxidant activity, resulting in the oxidation of glutathione. The ratio of reduced to oxidised glutathione is often used as a marker of the redox state