The theoretical background and research evidence supporting two alternative scenarios – worsening health and improving health at increasing life expectancy is analyzed. It is shown that the prevailing “longer life – worse health” theory is based on the logic that due to the reduced birth-rate and increased proportion of older citizens the process of population aging is taking place, leading to an

Specific hydroxy groups of the terminal disaccharide unit of globotriaosyl ceramide (Gb(3)Cer) were identified from binding studies with deoxyGb(3)Cer and verotoxins (VTs) [Nyholm, Magnusson, Zheng, Norel, Birmington-Boyd and Lingwood (1996) Chem. Biol. 3, 263-275]. Four such hydroxy groups (2", 4", 6" and 6') were each substituted with an amino group and the corresponding deoxyamino globotrioses

Popular Abstract in Swedish Avhandlingens huvudfråga är hur språket används i skolämnet naturkunskap i två mångkulturella gymnasieklassrum. Språket ses som vår viktigaste resurs för utveckling och lärande i olika skolämnen. Att elever får rikliga tillfällen att lära sig hantera ämnesrelevant språk blir enligt ett sådant synsätt avgörande för vilket språk de utvecklar och vad de lär sig. SpråkutvecThe purpose of the thesis is to investigate how language is used in the school subject Natural Science in two multi-cultural upper seconday classrooms. Previous research points to the fact that second language students are not successful in their school work. The reason usually given is the students' inadequate knowledge of their second language. Today's curricular directives of the Swedish school

Popular Abstract in Swedish Begreppen ‘participation’ och ‘empowerment’ är flitigt använda inom utvecklingsprojekt i tredje världen. Den betydelse som tillskrivs begreppen idag betonar en normativ tolkning, baserad på ett alternativt perspektiv på utveckling vilket innebär utgångspunkt från de människor utvecklingsprojeket berör snarare än västerländsk kunskap och expertis. Begreppen kräver detaljThe concepts participation and empowerment are frequently used in development projects in the third world. The meaning given to the concepts today signal a normative orientation, marking an alternative, people-centred approach to development. When used in development projects, the concepts demand detailed descriptions. They also demand project implementers, often local NGOs (non-government organis

Pathophysiological processes underlying intrauterine growth restriction are very complex and poorly understood. Growth restricted fetuses are at risk of hypoxia and, therefore, an early diagnosis of intrauterine growth restriction is important for initiation of fetal surveillance. Application of a three-dimensional ultrasound method for estimation of fetal weight promises better precision. Use of

Context Inpatients with nonvalvular atrial fibrillation, warfarin prevents ischemic stroke, but dose adjustment, coagulation monitoring, and bleeding limit its use. Objective To compare the efficacy of the oral direct thrombin inhibitor ximelagatran with warfarin for prevention of stroke and systemic embolism. Design, Setting, and Participants Double-blind, randomized, multicenter trial (20002001)

Cartilage oligomeric matrix protein (COMP) is a pentameric glycoprotein present in cartilage, tendon and ligament. Fragments of the molecule are present in the diseased cartilage, synovial fluid and serum of patients with knee injuries, osteoarthritis and rheumatoid arthritis. Although COMP is a substrate for several matrix metalloprotemases (MMPs), the enzymes responsible for COMP degradation in

The immune system has evolved specialized cellular and molecular mechanisms for targeting and regulating immune responses at epithelial surfaces. Here we show that small intestinal intraepithelial lymphocytes and lamina propria lymphocytes migrate to thymus-expressed chemokine (TECK). This attraction is mediated by CC chemokine receptor (CCR)9, a chemoattractant receptor expressed at high levels b

Luthers kombination av Guds-ords-mystik och kallelsemedvetande blir så tydlig att den just därför varit svår att förstå. Stolt gör upp med vanföreställningar som att retorik skulle utesluta spontanitet. Hon utgår från språkvetenskapliga iakttagelser: Luthers latinska och tyska språkanvändning står i intensivt beroende av varandra, och hans nyskapande insatser för det tyska språket kan inte isolera

Hosts can in principle employ two different strategies to defend themselves against parasites: resistance and tolerance. Animals typically exhibit considerable genetic variation for resistance (the ability to limit parasite burden). However, little is known about whether animals can evolve tolerance (the ability to limit the damage caused by a given parasite burden). Using rodent malaria in labora

In order to evaluate the success of simple heuristics we need to know more about how a relevant heuristic is chosen and how we learn which cues are relevant. These meta-abilities, we believe, are at the core of ecological rationality, rather than the individual heuristics.

Twenty-one boys (age range 5 months to 16 years) were followed during their stay at hospital. Total observation time was 120 h. Field notes were made immediately after each observation. These were then transcribed into a narrative text, which was analysed by content analysis. Six categories of needs were identified during non-threatening situations at the hospital: the need for activity, the need

A dynamic beam system loaded harmonically in the axial direction and constrained in the transverse direction is modelled using different theoretical descriptions. Results from an experimental set-up are compared to calculations using Bernoulli as well as Timoshenko beam theories. Some results from investigations of this beam system unveiling its chaotic nature have earlier been presented, but here