Type 2 diabetes mellitus (T2DM) is characterized by various combinations of ?-cell failure and insulin resistance leading to hyperglycemia and glucose intolerance. In order to maintain glucose tolerance in the insulin resistance state, increased insulin secretion is a requirement and it is because of inadequate islet adaptation that glucose intolerance develops in T2DM. The pathophysiology of T2DM

Studies of developmental stability can provide insights into the amount of genetic or environmental stress experienced by individuals or populations. In the present study, we used young plants of Acer platanoides (Norway maple) and Betula pendula (silver birch), two distantly related tree species with widely different leaf morphologies, to compare the expression of developmental instability in two

Syftet med projektet var att jämföra egenskaper hos s k högpresterande betong, d v s betong med mycket låga vattenbindetal (vbt) med motsvarande egenskaper hos normala betongkvaliteter. Studerade egenskaper är hydration, hållfasthetstillväxt och fukttransportegenskaper. I hydrationsstudierna ingår analys av hydratvattenmängd, kemisk krympning och värmeutveckling.

Background: The late-phase reaction (LPR) of the skin is an in vivo model of allergic inflammation. Objective: We sought to identify disease-associated pathways in the LPR using a network-based analysis. Methods: The LPR was examined by means of DNA microarray analysis of skin biopsy specimens from 10 patients with allergic rhinitis and 10 healthy control subjects. The results were further analyze

We present extensive density-functional theory (DFT) based calculations of the clean Rh(111) surface and of CO/Rh(111) overlayer systems. We study both ground-state structural properties and core-level shifts from differences in total energies at different coverages and adsorption sites. Most results are obtained using using norm-conserving or ultrasoft pseudopotentials. The overall reliability of

BACKGROUND: Almost every country in the Western world has great difficulties allocating enough financial resources to meet the needs in the care of the increasing elderly population. The main problem is common to all countries and concerns the efforts to meet elderly persons' needs on an individual level while still maintaining society's responsibility for distributing justice. The aim of this stu

En recension av Karin Röjdalens doktorsavhandling "'Men jag ville hjälpa'. Studier i Lars Ahlins 1940-talsnovellistik".

An error exponent for woven convolutional codes (WCC) with one tailbiting component code is derived. This error exponent is compared with that of the original WCC. It is shown that for WCC with outer warp, a better error exponent is obtained if the inner code is terminated with the tailbiting method. Furthermore, it is shown that the decoding error probability decreases exponentially with the squa

Popular Abstract in Swedish Blödarsjuka (hemofili) är en recessiv genetisk sjukdom orsakad av en defekt i X-kromosomen som leder till förlängd koagulationstid på grund av brist eller avsaknad av koagulationsfaktorerna VIII eller IX i blodet. Kvinnor är anlagsbärare, medan män utvecklar symptom. Hemofili förkommer sporadiskt som följd av spontan mutation likaväl som ärftligt inom vissa släkter, ochHaemophilia is a recessive genetic bleeding disorder in which coagulation time is prolonged due to the absence or malfunction of either of the serum proteins Factor VIII or IX. Joint destruction following repeated haemarthroses is the main cause of morbidity in haemophiliacs, and such arthropathy can be prevented or postponed by implementing prophylactic therapy with factor concentrate at an early

Vitamin D supplements have been used to prevent fractures. The effect may be mediated through increased bone mass, but also through reduced falling propensity. The aim of this study was to evaluate the association between 25-hydroxy vitamin D levels (25OHD), fall-associated variables (including tests of functional performance), and fracture in ambulatory women. At baseline 25OHD was measured in 98

The spectroelectrochemistry of camphor-bound cytochrome P450cam (P450cam) using gold electrodes is described. The electrodes were modified with either 4,4′-dithiodipyridin or sodium dithionite. Electrolysis of P450cam was carried out when the enzyme was in solution, while at the same time UV–visible absorption spectra were recorded. Reversible oxidation and reduction could be observed with both 4,

OBJECTIVES: To clarify whether the intensity of exposure to organic acid anhydrides (OAAs) is associated with the risk of sensitisation to these allergens. METHODS: The investigations were carried out in three different manufacturing plants (A, B, and C) where OAAs were used in the production of epoxy resins. Methyltetrahydrophthalic acid anhydride (MTHPA) was used in all three plants. The exposur