This thesis is focused on cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D), two concomitant conditions that appear with growing concern. In our work, we aim to improve the identification of individuals at-risk of cardiometabolic disease through the characterization of complex environmental exposures (i.e. diet, physical activity), that temporally vary, and the health effects on card

Renal dysfunction is a major risk factor for premature death and has been studied extensively. A new renal syndrome, shrunken pore syndrome (SPS), confers higher mortality in all studied populations. SPS is a condition in which cystatin C-based estimation of glomerular filtration rate (eGFRcystatin C) is ≥ 60% than creatinine-based estimation of glomerular filtration rate (eGFRcreatinine). We aime

Omstridda sexuella representationer har länge varit en konfliktyta i en västerländsk kontext. Vissa av dessa representationer har snabbt avfärdats som obscena, pornografiska, smutsiga, värdelösa eller ointressanta, medan andra har utmanat etablerade kategoriseringar och blivit föremål för intensiv debatt. För att undersöka och förstå de skriftliga sexuella representationernas historia i en svensk Transgressive sexual representations have long been a point of contention in Western societies. While some representations are easily disregarded as obscene, pornographic, smut, worthless or uninteresting, others disrupt established categorizations and are subject to heated debates. To map and understand the history of written, sexual representations in a Swedish context, I use the literature/porn

Retaining glycoside hydrolases are enzymes that catalyse the breakdown down of glycans through hydrolysis. Due to the double-replacement mechanism of the retaining glycoside hydrolases (GHs), which form an intermediate with part of the glycan covalently attached to the enzyme, some GHs are able to catalyse synthesis reactions called transglycosylation. In transglycosylation reactions a hydroxyl-co

This article presents the proceedings of a symposium presented at the 2004 ISBRA meeting in Mannheim, Germany, October 1, 2004. The organizers and chairpersons were Joseph H. Sisson, MD, and Claudia Spies, MD. The presentations were as follows: "Alcohol: Impact on Mucociliary Clearance"; "Alcohol and Alveolar Epithelial Dysfunction"; "The Reluctant Neutrophil in Lung Bacterial Host Defense During

Folkparkerna förstås idag ofta som baser för arbetarrörelsens kulturella projekt. Men allra tydligast under parkrörelsens första tre decennier hade de även en fundamental politiska roll. I denna presentation fokuserar vi på denna roll i ljuset av storstrejken 1909, där parkerna spelade en viktig roll för arbetarrörelsen som tydliga politiska platser på offentlighetens kant. När många andra platser

Galectins are a family of soluble proteins that bind β-D-galactopyranoside-containing glycoconjugates through their conserved carbohydrate-recognition domains. Galectins have emerged as promising drug targets due to their involvement in various pathological conditions, such as tumor growth and metastasis, autoimmune and inflammatory diseases, as well as metabolic disorders.This first part of the t

Biografisk artikel om medicine studeranden, läkaren, pedagogen och aktivisten Sofia Holmgren (1864-1953). Utökad (och med käll- och notapparat försedd) version av artikel tidigare publicerad digitalt i alumninyhetsbladet "Lundensaren" 2016.

Artikel om olika kopplingar - främst individuella - mellan 100-årsjubilerande musikern och humoristen Povel Ramel (1922-2007) och Lunds akademiska och studentikosa värld.

Introduction: The operational definitions of treatment response, partial response, and remission in obsessive-compulsive disorder (OCD) are widely used in clinical trials and regular practice. However, the clinimetric sensitivity of these definitions, that is, whether they identify patients that experience meaningful changes in their everyday life, remains unexplored.Objective: The objective was t

In recent decades, population increase and urban development have led to catastrophic environmental consequences. One of the principal objectives to achieve “sustainable development” is to find suitable landfills. Due to their physical characteristics, which have led to a lack of landfill sites and closeness to water bodies, agricultural fields, and residential areas, the cities of Javanrood, Pave

The energy transition of housing is accelerating in parallel with economic inequality reaching historically high levels. There is thus an opportunity to reduce inequalities in living conditions, but also a risk that the costs of the transition are unequally distributed and aggravate existing inequalities. In order to seize the opportunity for a just transition, and in tandem enable a meaningful inThe energy transition of housing is accelerating in parallel with economic inequality reaching historically high levels. There is thus an opportunity to reduce inequalities in living conditions, but also a risk that the costs of the transition are unequally distributed and aggravate existing inequalities. In order to seize the opportunity for a just transition, and in tandem enable a meaningful in

The postoperative course and final outcome after evacuation of subdural haematoma are described in 106 male patients in relation to their alcohol consumption. One-third of the patients were alcohol abusers, drinking at least 60 g of ethanol daily. Despite comparable head trauma, they had a significantly higher incidence of acute subdural haematomas and showed increased postoperative morbidity and

As part of aiming towards a non-smoking hospital environment, staff at a Copenhagen university hospital were offered participation in a differentiated smoking cessation programme. This consisted of lectures, group therapy, follow-up visits and individually tailored nicotine replacement therapy free-of-charge for six weeks. Three hundred and seventy-four employees started the programme, with 353 co

To assess the biodiversity consequences of contemporary land-use trends in Northern Europe, where agriculture is being replaced by forestry, we need a better knowledge of the contributions of constituting habitats to biodiversity. Here, we use purposefully collected data from 87 sites to model how agricultural habitats, including semi-natural pastures, sown temporary grassland (leys), cereal crops