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Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity

Oxygen-sensing mechanisms of eukaryotic multicellular organisms coordinate hypoxic cellular responses in a spatiotemporal manner. Although this capacity partly allows animals and plants to acutely adapt to oxygen deprivation, its functional and historical roots in hypoxia emphasize a broader evolutionary role. For multicellular life-forms that persist in settings with variable oxygen concentration

Nitrogen cycling in CMIP6 land surface models : Progress and limitations

The nitrogen cycle and its effect on carbon uptake in the terrestrial biosphere is a recent progression in earth system models. As with any new component of a model, it is important to understand the behaviour, strengths, and limitations of the various process representations. Here we assess and compare five land surface models with nitrogen cycles that are used as the terrestrial components of so

Maria Zoegas kaffe, nyskrivning av historiken för Zoegas kaffe, reklamkampanj.

Zoegas kaffe skapade kaffesorten Maria Zoega, som lanserades i slutet av september 2018. Detta kaffe var en direkt följd av företagets samverkan med projektet "Normkritiska perspektiv på lokal historia" där det under projektets försorg togs fram ny information som visade på Maria Zoegas betydelse för kaffeföretaget. Denna information ledde till att företagets historia skrevs om, att det lanserades

Blood Transcriptome Response to Environmental Metal Exposure Reveals Potential Biological Processes Related to Alzheimer's Disease

Alzheimer's disease (AD) is a neurodegenerative disease which is manifested by a progressive and irreversible decline of cognition, memory loss, a shortened attention span, and changes in personality. Aging and genetic pre-dispositions, particularly the presence of a specific form of apolipoprotein E (APOE), are main risk factors of sporadic AD; however, a large body of evidence has shown that mul

Low temperature scanning tunneling microscopy and spectroscopy on laterally grown InxGa1-xAs nanowire devices

Laterally grown InxGa1-xAs nanowires (NWs) are promising candidates for radio frequency and quantum computing applications, which, however, can require atomic scale surface and interface control. This is challenging to obtain, not least due to ambient air exposure between fabrication steps, which induces surface oxidation. The geometric and electronic surface structures of InxGa1-xAs NWs and conta

Nonlinear optics from off-energy closed orbits

This paper describes a novel scheme for correcting the second order (chromatic sextupole) magnet lattice and its deployment on a fourth generation multibend achromat electron storage ring. The method is analogous to the well-established linear optics from closed orbits scheme, but uses an off-energy orbit response matrix to characterize the second order optics of a lattice. The matrix is construct

Creative voices of the city : Articulating media, space and cultural identities by creative collectives in Southeast Asia

Denna avhandling undersöker den levda kulturen hos individer i kreativa kollektiv i Sydostasiatiska städer inom UNESCOs-nätverk. Sådana individer och deras kreativa kollektiv blir allt för ofta förbisedda av de kreativa städerna och deras officiella varumärkesbyggande narrativ. Denna monografi undersöker det kontinuerliga konstituerandet inom kreativa kollektiv i två städer: kreativa städ Bandung This thesis investigates the lived cultures of the individuals within collectives who are part of creative cities in Southeast Asia. Such individuals and their creative collectives are all too often rendered silent and unnoticed within the official narratives of creative city branding. This monograph thesis examines the articulation of creative collectives in two cities: the creative city of Bandu

Reconstructing Si cycling in transition zones during the Holocene using terrestrial and aquatic records

Global biogeochemical cycles and their interactions are an important parts of climate research. Investigations during the last decades emphasize the key role of diatoms – siliceous phytoplankton – in the silicon (Si) cycle as they are important carbon sequesters in both marine and lacustrine environments. Terrestrial Si cycling and especially fluxes across the vegetation-soil interface are highly

Reduced expression of C5a receptors on neutrophils from cord blood

AIM: To describe further functional deficiencies of neonatal neutrophils by measuring the expression of C5a receptors.METHODS: C5a uptake was measured using flow cytometry with fluorescein isothiocynate labelled recombinant C5a. The response of neutrophils to stimulation with C5a and fMLP was tested by measuring migration and exocytosis of myeloperoxidase and lactoferrin.RESULTS: C5a mean fluoresc

“Making the alliance even greater” : (Mis-)managing U.S.-Japan relations in the age of Trump

President Donald Trump’s “America First” policy questions the fundamentals of the global U.S.-led alliance network. Where other allies implemented hedging strategies, Japan’s Prime Minister Abe Shinzō pledged to “make the alliance even greater,” insisting that the bilateral ties were “airtight” and “stronger than ever before.” However, Trump’s approach to trade, détente with North Korea, and off-t

Adherent Intestinal Cells From Atlantic Salmon Show Phagocytic Ability and Express Macrophage-Specific Genes

Our knowledge of the intestinal immune system of fish is rather limited compared to mammals. Very little is known about the immune cells including the phagocytic cells in fish intestine. Hence, employing imaging flow cytometry and RNA sequencing, we studied adherent cells isolated from healthy Atlantic salmon. Phagocytic activity and selected gene expression of adherent cells from the distal intes

Incomplete Sterility of Chromosomal Hybrids : Implications for Karyotype Evolution and Homoploid Hybrid Speciation

Heterozygotes for major chromosomal rearrangements such as fusions and fissions are expected to display a high level of sterility due to problems during meiosis. However, some species, especially plants and animals with holocentric chromosomes, are known to tolerate chromosomal heterozygosity even for multiple rearrangements. Here, we studied male meiotic chromosome behavior in four hybrid generat

Livslängddimensionering av träkonstruktioner : Utveckling av nytt verktyg

Trä som byggnadsmaterial används till allt från trädäck och möbler till broar och höghus. Enbart i Sverige används 5-6 miljoner m3 sågade barrträvaror årligen varav ungefär hälften används i byggtillämpningar [2]. Till bärande konstruktioner inom hus- och brobyggnad nyttjas framförallt gran och furu men för trädäck och träpanel finns det en uppsjö av olika träslag och behandlingar på marknaden. Vi

Phase Modulation Two-Photon Microscopy of Hybrid Halide Perovskite

Recently, intense research activities have been focused on solution-processed hybrid lead halide perovskite semiconductors which are being developed for the solar-cell, light emitting diode (LED), and lasing applications. To optimize and fabricate a competitive perovskite-based optoelectronic device, the fundamental studies of the electronic structure, photo-generated carrier dynamics as well as t