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Total Hip Bone Mineral Density as an Indicator of Fracture Risk in Bisphosphonate-Treated Patients in a Real-World Setting

Bone mineral density (BMD) is an established measure used to diagnose patients with osteoporosis. In clinical trials, change in BMD has been shown to provide a reliable estimate of fracture risk reduction, and achieved BMD T-score has been shown to reflect the near-term risk of fracture. We aimed to test the association between BMD T-score and fracture risk in patients treated for osteoporosis in

2021 ISHNE/HRS/EHRA/APHRS collaborative statement on mHealth in Arrhythmia Management : Digital Medical Tools for Heart Rhythm Professionals: From the International Society for Holter and Noninvasive Electrocardiology/Heart Rhythm Society/European Heart Rhythm Association/Asia Pacific Heart Rhythm Society

This collaborative statement from the International Society for Holter and Noninvasive Electrocardiology/Heart Rhythm Society/European Heart Rhythm Association/Asia Pacific Heart Rhythm Society describes the current status of mobile health (“mHealth”) technologies in arrhythmia management. The range of digital medical tools and heart rhythm disorders that they may be applied to and clinical decisi

Prevalence of Celiac Disease Autoimmunity in Ethiopian Pregnant Women: A Cross Sectional Study from the Oromia region

Celiac disease is a chronic small bowel disease induced by ingestion of gluten in genetically susceptible individuals affecting 1% among Caucasians in the Western world. The prevalence of celiac disease is still unknown in most developing countries, especially in Africa which suffer from lack of resources to perform screening of the general population. The aim of this study was to determine the pr

The impact of free returns on online purchase behavior : Evidence from an intervention at an online retailer

Whether free returns create economic value for online retailers is a question of increasing importance. Using order-level data from an online fashion retailer in Sweden, we investigate the introduction of free returns for customers in Denmark starting November 1, 2017, but not for customers in Sweden, Norway, Finland, France, Germany, and the rest of Europe (the control group). Using difference-in

From overtourism to undertourism: exploring the mediatization of place brands

Overtourism encapsulates the zeitgeist of contemporary tourism and was - for a few years - the buzzword within media reports on tourism. It gained attention as an unsustainable consequence of the intensification of place management practices in urban economic planning strategy. Stories about “the invasion” of visitors into a number of popular European cities frequently circulated in news and socia

Prevention of posttraumatic osteoarthritis at the time of injury : Where are we now, and where are we going?

This overview of progress made in preventing post-traumatic osteoarthritis (PTOA) was delivered in a workshop at the Orthopaedics Research Society Annual Conference in 2019. As joint trauma is a major risk factor for OA, defining the molecular changes within the joint at the time of injury may enable the targeting of biological processes to prevent later disease. Animal models have been used to te

Health-Related Quality of Life, Dysphagia, Voice Problems, Depression, and Anxiety After Total Laryngectomy

Objectives/Hypothesis: The aims were to determine health-related quality of life (HRQoL), including voice problems, dysphagia, depression, and anxiety after total laryngectomy (TL), and investigate the associations between HRQoL and the late effects. Study Design: Cross-sectional study. Methods: 172 participants having received a TL 1.6 to 18.1 years ago for laryngeal/hypopharyngeal cancer filled

Genotype–Phenotype Relations for the Atypical Parkinsonism Genes : MDSGene Systematic Review

This Movement Disorder Society Genetic mutation database Systematic Review focuses on monogenic atypical parkinsonism with mutations in the ATP13A2, DCTN1, DNAJC6, FBXO7, SYNJ1, and VPS13C genes. We screened 673 citations and extracted genotypic and phenotypic data for 140 patients (73 families) from 77 publications. In an exploratory fashion, we applied an automated classification procedure via a

Mapping prostatic microscopic anisotropy using linear and spherical b-tensor encoding : A preliminary study

Purpose: Tensor-valued diffusion encoding provides more specific information than conventional diffusion-weighted imaging (DWI), but has mainly been applied in neuroimaging studies. This study aimed to assess its potential for the imaging of prostate cancer (PCa). Methods: Seventeen patients with histologically proven PCa were enrolled. DWI of the prostate was performed with linear and spherical t

Combined diffusion-relaxometry microstructure imaging : Current status and future prospects

Microstructure imaging seeks to noninvasively measure and map microscopic tissue features by pairing mathematical modeling with tailored MRI protocols. This article reviews an emerging paradigm that has the potential to provide a more detailed assessment of tissue microstructure—combined diffusion-relaxometry imaging. Combined diffusion-relaxometry acquisitions vary multiple MR contrast encodings—

Trust in researchers and researchers' statements in large carnivore conservation

Human–wildlife interactions occur when humans and wildlife overlap in the same landscapes. Due to the growing human population, the number of interactions will continue to increase, and in some cases, develop further into social conflicts. Conflicts may occur between people disagreeing about wildlife conservation or arguing over which wildlife management measures should be taken. Social conflicts

Synthesis of Biobased Block Copolymers Using A Novel Methacrylated Methyl Salicylate and Poly(3-Hydroxybutyrate)

A novel biobased vinyl monomer was synthesized by the reaction of methyl salicylate with methacrylic anhydride. The resulting salicylate based monomer was polymerized by reversible addition fragmentation transfer (RAFT) polymerizations using two or three trithiocarbonate functionalized poly(3-hydroxybutyrate) macro agents. The molecular structures of the obtained polymers were confirmed by NMR spe

Infant outcome after active management of early-onset fetal growth restriction with absent or reversed umbilical artery blood flow

Objective: To describe the short- and long-term outcomes of infants with early-onset fetal growth restriction (FGR) and umbilical artery absent or reversed end-diastolic flow (AREDF), delivered before 30 weeks' gestation and managed proactively. Methods: This was a retrospective cohort study of fetuses delivered for fetal indication before 30 completed weeks' gestation that had early-onset FGR (de

Genetic variants in susceptibility to childhood acute lymphoblastic leukemia

The present study was aimed at identifying genetic variants in susceptibility to childhood acute lymphoblastic leukemia (ALL) through replication and validation of polymorphisms selected from two genome wide association studies. The first part of the study was based on the replication of polymorphisms selected from a previously conducted genome wide scan using 50K DNA-SNP microarrays. 47 selected

Mission Impossible? : The Moral Discomfort among Swedish and Norwegian Welfare Bureaucrats Encountering Refugees

This article builds on qualitative interviews with employees in Norwegian and Swedish welfare state institutions and explores how they experience and make sense of their work with newly arrived refugees. The task of these street-level bureaucrats was to care for and simultaneously push the refugees to quickly become working taxpayers. Both as fellow human beings and as bureaucrats, however, our in

Cohesion, collaboration and the struggle of creating online learning communities: Development and validation of an online collective efficacy scale

A number of strategies have emerged over the last decades to guide the development of online learning com- munities where members share, augment and co-create information but few tools to measure their success. This paper suggests that some online communities’ success can be understood through the lens of online collective efficacy. Albert Bandura introduced the idea of collective efficacy as an e

Dersim 1937-38 : Shifts and continuities in the state discourse and reasoning under Kemalism and Erdoğanism

This chapter analyzes the changing accounts of Dersim from 1937 to 1938 in the dominant state discourse as well as subjugated narratives of the oppressed and argues that Erdoğan’s Dersim ‘apology’ instrumentalized the traumatic history of Dersim and the Dersim community not only to disgrace his rival party CHP and to discredit its Dersimli leader Kemal Kılıçdaroğlu, but also to challenge Kemalism

Convalescence plasma treatment of COVID-19 : results from a prematurely terminated randomized controlled open-label study in Southern Sweden

OBJECTIVE: Convalescent plasma has been tried as therapy for various viral infections. Early observational studies of convalescent plasma treatment for hospitalized COVID-19 patients were promising, but randomized controlled studies were lacking at the time. The objective of this study was to investigate if convalescent plasma is beneficial to hospitalized patients with COVID-19.RESULTS: Hospitali