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Towards understanding critical flows - a literature review

Critical infrastructure such as transportation, power, telecommunication and water supply systems accommodate and enable flows of essential goods and services that modem societies are highly dependent upon. These critical flows connect countries, organizations and communities, and are imperative for upholding vital societal functions. Disruptions of such flows hold the potential of severe and pote

Preserving children's fertility: two tales about children's right to an open future and the margins of parental obligations

The sources, extent and margins of parental obligations in taking decisions regarding their children’s medical care are subjects of ongoing debates. Balancing children’s immediate welfare with keeping their future open is a delicate task. In this paper, we briefly present two examples of situations in which parents may be confronted with the choice of whether to authorise or demand non-therapeutic

Managing multiple risks in land use planning – a literature review

Many risks addressed in land use planning, such as flooding and accidents involving hazardous materials, have widely different characteristics which makes them difficult to compare. Yet, these risks sometimes need to be considered together in order to support decision-making. Furthermore, risks can sometimes affect each other, which differentiate the land use planning context from situations where

Writers blocked: on the wrongs of research co-authorship and some possible strategies for improvement

The various problems associated with co-authorship of research articles have attracted much attention in recent years. We believe that this (hopefully) growing awareness is a very welcome development. However, we will argue that the particular and increasing importance of authorship and the harmful implications of current practices of research authorship for junior researchers have not been emphas

Postmenopausal Motherhood Reloaded: Advanced Age and In Vitro Derived Gametes

In this paper we look at the implications of a prospective emerging technology for the case in favor of, or against, postmenopausal motherhood. Technologies such as in vitro derived gametes (sperm and eggs derived from non-reproductive cells) have the potential to influence the ways in which reproductive medicine is practiced, and will bring new dimensions to debates in this area. We explain what

Will Artificial Gametes End Infertility?

In this paper we will look at the various ways in which infertility can be understood and at how need for reproductive therapies can be construed. We will do this against the background of research with artificial gametes (AGs). Having explored these questions we will attempt to establish the degree to which technologies such as AGs could expand the array of choices that people have to reproduce a

Artificial gametes : perspectives of geneticists, ethicists and representatives of potential users

Several threads of research towards developing artificial gametes are ongoing in a number of research labs worldwide. The development of a technology that could generate gametes in vitro has significant potential for human reproduction, and raises a lot of interest, as evidenced by the frequent and extensive media coverage of research in this area. We have asked researchers involved in work with a

Artificial gametes and the ethics of unwitting parenthood

In this paper, we explore the ethical and legal implications of a hypothetical use of artificial gametes (AGs): that of taking a person’s cells, converting them to artificial gametes and using them in reproduction – without that person’s knowledge or consent. We note the common reliance on genetic understandings of parenthood in the law, and suggest that injustices may arise if unwitting genetic p

Families : Beyond the Nuclear Ideal

This book examines, through a multi-disciplinary lens, the possibilities offered by relationships and family forms that challenge the nuclear family ideal, and some of the arguments that recommend or disqualify these as legitimate units in our societies. That children should be conceived naturally, born to and raised by their two young, heterosexual, married to each other, genetic parents; that th

PhaseGAN : a deep-learning phase-retrieval approach for unpaired datasets

Phase retrieval approaches based on deep learning (DL) provide a framework to obtain phase information from an intensity hologram or diffraction pattern in a robust manner and in real-time. However, current DL architectures applied to the phase problem rely on i) paired datasets, i. e., they are only applicable when a satisfactory solution of the phase problem has been found, and ii) the fact that

Untangling fracture risk in monoclonal gammopathy of undetermined significance : A population-based cohort study

Objective: Monoclonal gammopathy of undetermined significance (MGUS) is the asymptomatic precursor of multiple myeloma (MM). Lytic bone lesions and fractures are hallmarks of MM and although there are no lytic lesions in MGUS, it has also been associated with fractures. The causes of fractures in MGUS are currently unclear but potential causes include inherent MGUS bone disease, undiagnosed MM, an

Analysis of pluvial flood damage costs in residential buildings : A case study in Malmö

Pluvial flood damage to residential buildings causes a significant part of direct tangible flood losses. In this study, we investigate the non-hazard variables and sewer system types in relation to damage costs in the city of Malmö, Sweden. A comprehensive data set of around 1000 records of direct damage to residential buildings from a cloudburst event on 31 August 2014 in Malmö, Sweden has been a

Question intonation in Southern Swedish

Swedish has been generally assumed not to have any well-defined question intonation. However, with respect to Southern Swedish, Lindblad & Gårding (1973) present data showing final rises in polar (Y/N) questions. Gårding (1979) also assumes a broader and higher F0 range in Y/N questions than in statements, particularly on the final focussed word. The present study investigates the extent to wh