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NETs (neutrophil extracellular traps) have been described as a fundamental innate immune defence mechanism. During formation of NETs, the nuclear membrane is disrupted by an as-yet unknown mechanism. In the present study we investigated the role of human cathelicidin LL-37 in nuclear membrane disruption and formation of NETs. Immunofluorescence microscopy revealed that 5 μM LL-37 significantly fac
Metal affinity tags have been fused to proteins and demonstrated to function as tools in protein purification, protein stabilisation, quantitative metal analysis and metal tolerance of bacteria and plants. In biotechnological applications proteins frequently have to function in nonnatural environments with harsh conditions which impose requirements for high stability on the proteins. Metal affini
In this paper unequal error-correcting capabilities of convolutional codes are studied. State-transition graphs are used for investigating the error-correcting capabilities for specific inputs or outputs of given convolutional encoding matrices. Active burst input- and output-distances are defined and shown to be generalizations of the active burst distance. These new distances provide better esti
Humans have an impressive ability to communicate precise social intentions and desires with their voice - through vocal attitudes. Previous studies have shown how isolated acoustic features such as pitch can convey social attitudes, but have mostly worked with single attitudes and have not controlled for inter-speaker variability. Thus, the vocal behaviours used to produce social attitudes remain
False positive recall is a major issue in breast cancer screening and the introduction of artificial intelligence (AI) might affect which women who are unnecessarily recalled. We have investigated how an AI system works on false positive recalls at screening and compared with radiologist findings. Two-view digital mammography (DM) examinations from 656 recalled women (136 with screening detected c
BACKGROUND: Movement disorders are frequent in patients with inborn errors of metabolism (IEMs) but poorly recognized, particularly by nonmovement disorder specialists. We propose an easy-to-use clinical screening tool to help recognize movement disorders.OBJECTIVE: The aim is to develop a user-friendly rapid screening tool for nonmovement disorder specialists to detect moderate and severe movemen
Intrathymic development of committed progenitor (pro)-T cells from multipotent hematopoietic precursors offers an opportunity to dissect the molecular circuitry establishing cell identity in response to environmental signals. This transition encompasses programmed shutoff of stem/progenitor genes, upregulation of T cell specification genes, proliferation, and ultimately commitment. To explain thes
Mammographic sensitivity in breasts with higher density has been questioned. Higher breast density is also linked to an increased risk for breast cancer. Even though digital breast tomosynthesis (DBT) offers an attractive solution, for varied reasons it has not yet been widely adopted in screening. An alternative could be to boost the performance of standard mammography by using computer-aided det
Breast cancer screening is predominantly performed using digital mammography (DM), but higher sensitivity has been demonstrated with digital breast tomosynthesis (DBT). A partial DBT screening in selected groups with a clear benefit from DBT might be more feasible than a full implementation, and using artificial intelligence (AI) to select women for DBT might be a possibility. This study used data
Beräkningsmodelleringar har blivit ett allt mer viktigt verktyg inom biologisk forskning. Genom att utföra datorsimuleringar av modeller blir det möjligt att testa hur teorier om biologiska system förhåller sig till experimentell data. Simuleringar kan även användes som ersättning för potentiellt ogenomförbara experiment. En välkonstruerade modells förmåga att göra förutsägelser kan hjälpa till atComputational modelling is becoming an increasingly important tool in biological research. By performing computer simulations of models, it becomes possible to test theories about a biological system against experimental data. Simulations can also be used as a replacement for experiments otherwise unattainable. Well-constructed models have great predictive power which helps improve experimental pr
A grazing-incidence Rowland spectrometer with a collimating element for resonant inelastic soft X-ray scattering at the Veritas beamline at MAX IV, Lund, Sweden, is presented. The instrument is designed to operate in the 250–950 eV range, providing >30000 resolving power in first order. The inherent temporal resolution of the delay-line detector enables time-resolved experiments on the 270 ps time
The latest version of the Swiss standard for building acoustics (SIA181) introduced a new measurement method, based on a balanced- Arm hammer, for evaluating the decoupling performance of service equipment. This method was developed for reproducing in a standard manner the manipulation of service equipment in bathrooms and kitchens. In this study, we are investigating the relevance of such method
Colony stimulating factor 1 receptor (CSF1R)-related leukoencephalopathy is a rare, genetic disease caused by heterozygous mutations in the CSF1R gene with rapidly progressive neurodegeneration, behavioral, cognitive, motor disturbances. Objective: To describe four cases of CSF1R-related leukoencephalopathy from three families with two different pathogenic mutations in the tyrosine kinase domain o
OBJECTIVES: Combination chemotherapy regimens have shown promising results in patients with metastatic colorectal cancer. However, only very few studies have studied the effect of palliative chemotherapy in peritoneal carcinomatosis (PC) and no data are present incorporating biological therapies in the treatment of PC in colorectal cancer.METHODS: By means of merging with the regional Eindhoven Ca
Kurslitteratur MVEN16_HT19_16okt19 Kurslitteratur MVEN16 2019-10-16 MVEN16 KURSLITTERATUR, HT19 OBS! Vissa artiklar kan ändras/tillkomma under kursens gång! Kursböcker Boyce, T. and Lewis, J., eds. (2009). Climate Change and the Media. Global Crises and the Media Series. Peter Lang Pub Inc. (OBS! om svårtillgänglig, tillhandahålles utvalda kapitel under kursens gång) Bulkeley, H. and Newell, P. (2
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/kurslitteratur_mven16_ht19_16okt19.pdf - 2026-01-17
Microsoft PowerPoint - AI dagen LUCE AIML@LU Kick-off WS 29 MAY 2018 AIML@LU • Already a lot of activity within AI an ML – Historically – at Lund University – within industry and society in the region. – As will be shown today • What can a network help with? – Stronger network (for new courses, research, innovations) – Communication – … • How should we develop the network? Agenda AM 10:15-12:00 In
https://www.ai.lu.se/sites/ai.lu.se/files/2021-03/AIML_WS_20180529_handout_1s.pdf - 2026-01-17
We describe an entomological dual-band 808 and 980 nm lidar system which has been implemented in a tropical cloud forest (Ecuador). The system was successfully tested at a sample rate of 5 kHz in a cloud forest during challenging foggy conditions (extinction coefficients up to 20 km–1). At times, the backscattered signal could be retrieved from a distance of 2.929 km. We present insect and bat obs
INTRODUCTION: Recently, an increasing number of tau tracers have become available. There is a need to standardize quantitative tau measures across tracers, supporting a universal scale. We developed several cortical tau masks and applied them to generate a tau imaging universal scale. METHOD: One thousand forty-five participants underwent tau scans with either 18F-flortaucipir, 18F-MK6240, 18F-PI2
This paper describes the active burst distance for convolutional codes. The unequal error protection for information sequences are used to formulate a theorem on the error-correcting capability of the generator matrix and set state paths in the encoder state-transition diagram correspond to code sequences. Therefore the active-distance concepts are used to characterize the error patterns
Mitochondrial abnormalities may be involved in PTSD, although few studies have examined this. Mitochondrial DNA copy number (mtDNAcn) in blood cells is an emerging systemic index of mitochondrial biogenesis and function. The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales.
