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The racemic 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[1-(pyridin-2-yl)ethyl]propanamide, 1, has previously been identified as a potent but unselective inhibitor of diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3). Herein we describe synthesis and evaluation of 55 compounds in this class. It was found that the stereochemistry is of great importance for both selectivity and potency and that subs
OBJECTIVES: Digital breast tomosynthesis (DBT) can detect more cancers than the current standard breast screening method, digital mammography (DM); however, it can substantially increase the reading workload and thus hinder implementation in screening. Artificial intelligence (AI) might be a solution. The aim of this study was to retrospectively test different ways of using AI in a screening workf
Beräkningsmodelleringar har blivit ett allt mer viktigt verktyg inom biologisk forskning. Genom att utföra datorsimuleringar av modeller blir det möjligt att testa hur teorier om biologiska system förhåller sig till experimentell data. Simuleringar kan även användes som ersättning för potentiellt ogenomförbara experiment. En välkonstruerade modells förmåga att göra förutsägelser kan hjälpa till atComputational modelling is becoming an increasingly important tool in biological research. By performing computer simulations of models, it becomes possible to test theories about a biological system against experimental data. Simulations can also be used as a replacement for experiments otherwise unattainable. Well-constructed models have great predictive power which helps improve experimental pr
Senior lecturer Contact details Email: anders [dot] ahlstrom [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageAnders Ahlströms profile in Lund University research portalOther affiliations Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Changing Climate Profile area member LU Profile Area: Nature-
https://www.nateko.lu.se/anders-ahlstrom - 2026-07-15
Project coordinator Contact details Email: stefan [dot] olin [at] mgeo [dot] lu [dot] se Phone: +46 46 222 38 30Organisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageStefan Olins profile in Lund University research portalOther affiliations Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Changing Climate Profile area member LU P
https://www.nateko.lu.se/stefan-olin - 2026-07-15
1 M al m ö A rt A ca de m y 20 17 – 20 18 Masters of Fine Arts – Year 1 Masters of Fine Arts – Critical & Pedagogical Studies – Year 1 Bachelor of Fine Arts – Year 2 Bachelor of Fine Arts – Year 1 2M al m ö A rt A ca de m y M al m ö A rt A ca de m y 20 17 – 2 01 8 20 17 – 2 01 8 20 17 – 2 01 8 3 Andreas Bentdal Amble Rannveig Jónsdóttir Carl-Oskar Jonsson Cecilia Kanthi Jonsson Gabriel Karls
https://www.khm.lu.se/en/sites/khm.lu.se.en/files/yearbook2_2018.pdf - 2026-07-16
Microsoft Word - COSM10 course schedule 2021.docx Centre for East and South-East Asian Studies COSM10 Asian Studies: Asian Studies, 6 credits Autumn semester 2021, 30 August – 22 September Course schedule (Preliminary 2021-06-16) Course information The course offers an introduction to critical, interdisciplinary Asian Studies, its historical origin, research history, and some cross-cutting issues
https://www.ace.lu.se/sites/ace.lu.se/files/2021-06/COSM10%20course%20schedule%202021.pdf - 2026-07-16
Date: 2026-01-16 Author: Martin Jönsson, Trainee, Universities in South Sweden Brussels Representation, autumn semester 2025 The future of the European Common Agricultural Policy in the next Multiannual Financial Framework Where CAP 2028–2034 stands: institutions, actors and next steps Part 3 of 3 Summary: In the European Parliament, AGRI remains the lead committee working on CAP, but real influen
https://www.mgeo.lu.se/en/sites/mgeo.lu.se.en/files/2026-03/CAP_PolicyBriefing_3_2026_0.pdf - 2026-07-16
Förnamn Efternamn Beskrivning Prince Young Aboagye 263041 Ekonomisk historia - Forskare Nam Aghaee 263141 Informatik - Univlekt Fawad Ahmad 263011 Företagsekonomi - Postdoktor Andrea Algård 263131 Handelsrätt - Univadj Mats Alvesson 263011 Företagsekonomi - Professor Göran Anderson 263011 Företagsekonomi - Univlekt Fredrik Andersson 263021 Nationalekonomi - Professor Fredrik N G Andersson 263021 N
https://www.lusem.lu.se/internal/sites/lusem.lu.se.internal/files/2026-07/rostlangd_2026_07_13_faststa%CC%88lld.pdf - 2026-07-16
The incidence of melanoma is rising and will require more efficient diagnostic procedures to meet a growing demand. Excisional biopsy and histopathology is still the standard, which often requires multiple surgical incisions with increasing margins due inaccurate visual assessment of where the melanoma borders to healthy tissue. This challenge stems, in part, from the inability to reliably delinea
Background: Peritoneal carcinomatosis (PC) from colorectal cancer (CRC) is a metastatic condition associated with poor prognosis. Tumor dissemination within the peritoneal cavity is influenced by inflammatory responses, immune activation, and tumor-matrix interactions, particularly following surgical trauma. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC
Gastrointestinal (GI) interventional endoscopy has evolved into a cornerstone of modern gastroenterology, offering minimally invasive solutions for complex conditions. However, these procedures are not without risk, particularly with respect to post-procedural infections. While rare, such infections can have significant clinical consequences and are increasingly recognized as a public health conce
Aim: The treatment of peritoneal surface malignancies ranges from palliative care to full cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy, HIPEC. Ongoing monitoring of patient recruitment and volume is usually carried out through dedicated registries. With multiple registries available worldwide, we sought to investigate the nature, extent and value of existing worldwide CRS an
Objective: Diabetic foot ulceration (DFU) has the potential to deteriorate rapidly without prompt assessment and treatment. The aim of this study was to assess the referral patterns for DFU, from primary care to specialised diabetes foot care units. Method: A two-part, quantitative, online questionnaire was administered to GPs across four countries in Europe: France, the UK, Germany and Spain. The
Familial myelodysplastic syndromes arise from haploinsufficiency of genes involved in hematopoiesis and are primarily associated with early-onset disease. Here we describe a familial syndrome in seven patients from four unrelated pedigrees presenting with myelodysplastic syndrome and loss of chromosome 7/7q. Their median age at diagnosis was 2.1 years (range, 1-42). All patients presented with thr
Major climate and ecological changes affect the world’s oceans leading to a number of responses including increasing water temperatures, changing weather patterns, shrinking ice-sheets, temperature-driven shifts in marine species ranges, biodiversity loss and bleaching of coral reefs. In addition, ocean pH is falling, a process known as ocean acidification (OA). The root cause of OA lies in human
In the recent project BENCHOP–the BENCHmarking project in Option Pricing we found that Stochastic and Local Volatility problems were particularly challenging. Here we continue the effort by introducing a set of benchmark problems for this type of problems. Eight different methods targeted for the Stochastic Differential Equation (SDE) formulation and the Partial Differential Equation (PDE) formula
Mitochondrial abnormalities may be involved in PTSD, although few studies have examined this. Mitochondrial DNA copy number (mtDNAcn) in blood cells is an emerging systemic index of mitochondrial biogenesis and function. The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales.
Multiple guidelines exist for the management of aortic stenosis (AS). We systematically reviewed current guidelines and recommendations, developed by national or international medical organizations, on management of AS to aid clinical decision-making. Publications in MEDLINE and EMBASE between 1 June 2010 and 15 January 2021 were identified. Additionally, the International Guideline Library, Natio
