Sökresultat

Human Group IIA secreted phospholipase A2 (hGIIA) is an acute phase protein with bactericidal activity against Gram-positive bacteria. Infection models in hGIIA transgenic mice have suggested the importance of hGIIA as an innate defense mechanism against the human pathogens Group A Streptococcus (GAS) and Group B Streptococcus (GBS). Compared to other Gram-positive bacteria, GAS is remarkably resi

Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and oxidoreductase NAD-binding domain containing 1 (OXNAD1) genes. The UV-signature mutations occurred at

The incidence of melanoma is rising and will require more efficient diagnostic procedures to meet a growing demand. Excisional biopsy and histopathology is still the standard, which often requires multiple surgical incisions with increasing margins due inaccurate visual assessment of where the melanoma borders to healthy tissue. This challenge stems, in part, from the inability to reliably delinea

Changes in forest cover have a strong effect on climate through the alteration of surface biogeophysical and biogeochemical properties that affect energy, water and carbon exchange with the atmosphere. To quantify biogeophysical and biogeochemical effects of deforestation in a consistent setup, nine Earth system models (ESMs) carried out an idealized experiment in the framework of the Coupled Mode

We report the construction of the first complete genetic linkage map of the laboratory rat. By testing 1171 simple sequence length polymorphisms (SSLPs), we have identified 432 markers that show polymorphisms between the SHR and BN rat strains and mapped them in a single (SHR × BN) F2 intercross. The loci define 21 large linkage groups corresponding to the 21 rat chromosomes, together with a pair

Guidelines for the diagnosis and management of aortic regurgitation (AR) contain recommendations that do not always match. We systematically reviewed clinical practice guidelines and summarized similarities and differences in the recommendations as well as gaps in evidence on the management of AR. We searched MEDLINE and Embase (1 January 2011 to 1 September 2021), Google Scholar, and websites of

Over recent decades, management of people with hemophilia (PwH) has been greatly improved by scientific advances that have resulted in a rich and varied therapeutic landscape. Nevertheless, treatment limitations continue to drive innovation, and emerging options have the potential to realize further improvement. We advocate four general principles to optimize benefits from innovation: individualiz

The dynamics of chemical reactions in solution are of paramount importance in fields ranging from biology to materials science. Because the hydrogen-bond network and proton dynamics govern the behavior of aqueous solutions, they have been the subject of numerous studies over the years. Here, we report the observation of a previously unknown associative state in the hydroxide ion that forms when a

Context. The coupling between the dark matter (DM) halo and the stellar disc is a key factor in galactic evolution. While the interaction between structures like the Galactic bar and DM halos has been explored (e.g. slowing down of the bar due to dynamical friction), the effect of spiral arms on the DM halo distribution has received limited attention. Aims. We aim to detect and characterize the in

Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is an extensive procedure with considerable morbidity. Since only few hospitals perform CRS + HIPEC, this might lead to confounded outcomes between hospitals when audited. This study aims to compare outcomes between peritoneally metastasized (PM) colon cancer patients treated with CRS + HIPEC and patients undergoing

Minsk Declaration of Women Leaders Adopted at International Forum - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analys

https://rwi.lu.se/2016/06/27/minsk-declaration-of-women-leaders-adopted-at-international-forum/ - 2026-01-15

human rights and the environment Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation o

https://rwi.lu.se/news-tags/human-rights-and-the-environment/ - 2026-01-15

Docent | Universitetslektor Kontaktinformation E-post: maja [dot] sager [at] genus [dot] lu [dot] seOrganisation Genusvetenskap Hämtställe: 31 WebbplatsMaja Sagers profil i Lunds universitets forskningsportalAndra roller Profilområdesmedlem LU profilområde: Mänskliga rättigheter My research interests are citizenship, nation, globalisation, migration and asylum rights from an intersectional feminis

https://www.genus.lu.se/maja-sager - 2026-01-17

Forskare Kontaktinformation E-post: fredrik [dot] lagergren [at] mgeo [dot] lu [dot] se Telefon: +46 46 222 39 76Organisation Institutionen för naturgeografi och ekosystemvetenskap Rumsnummer: 449 Hämtställe: 16 WebbplatsFredrik Lagergrens profil i Lunds universitets forskningsportalAndra roller Medlem i Strategiskt forskningsområde BECC: Biodiversity and Ecosystem services in a Changing Climate P

https://www.nateko.lu.se/sv/fredrik-lagergren - 2026-01-17

Universitetslektor Kontaktinformation E-post: vasna [dot] ramasar [at] keg [dot] lu [dot] seOrganisation Institutionen för kulturgeografi och ekonomisk geografi Hämtställe: 16 WebbplatsVasna Ramasars profil i Lunds universitets forskningsportalAndra roller Universitetslektor Humanekologi Gästforskare LUCSUS Profilområdesmedlem LU profilområde: Mänskliga rättigheter Docent Institutionen för kulturg

https://www.keg.lu.se/vasna-ramasar - 2026-01-17

Senior lecturer Contact details Email: anders [dot] ahlstrom [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageAnders Ahlströms profile in Lund University research portalOther affiliations Senior lecturer Dept of Physical Geography and Ecosystem Science Member of Strategic Research Area BECC: Biodiversity and Ecosystem services i

https://www.nateko.lu.se/anders-ahlstrom - 2026-01-17

Metal affinity tags have been fused to proteins and demonstrated to function as tools in protein purification, protein stabilisation, quantitative metal analysis and metal tolerance of bacteria and plants. In biotechnological applications proteins frequently have to function in nonnatural environments with harsh conditions which impose requirements for high stability on the proteins. Metal affini

In this paper unequal error-correcting capabilities of convolutional codes are studied. State-transition graphs are used for investigating the error-correcting capabilities for specific inputs or outputs of given convolutional encoding matrices. Active burst input- and output-distances are defined and shown to be generalizations of the active burst distance. These new distances provide better esti