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Popular Abstract in Swedish I avhandlingen presenteras en analys av den svenska rösträttsrörelsens diskursgemenskap mellan åren 1887 och 1902. Studien fokuserar huvudsakligen på rörelsens kärna; Sveriges allmänna rösträttsförbund. Denna organisation, ledd av en överstyrelse och ett verkställande utskott i Stockholm, fungerade som rörelsens nationella ramverk under perioden 1890-1900. TraditionelltThe People, the Axe and the Root of Injustice: the Swedish Suffrage Movement's Discourse Community 1887?1902, its Production of Meaning and the Concept of Democracy In this thesis, I present a study of the Swedish suffrage movement's discourse community. The analyses focus primarily on the core of this movement, the Swedish Public Suffrage Association (Sveriges allmänna rösträttsförbund). This as

While the Sun is generally more eruptive during its maximum and declining phases, observational evidence shows certain cases of powerful solar eruptions during the quiet phase of solar activity. Occurring in the weak Solar Cycle 14 just after its minimum, the extreme space weather event in 1903 October-November is one of these cases. Here, we reconstruct the time series of geomagnetic activity bas

Cloud computing technology provides the means to share physical resources among multiple users and data center ten- ants by exposing them as virtual resources. There is a strong industrial drive to use similar technology and concepts to provide timing sensitive services. One such is virtual net- working services, so called services chains, which consist of several interconnected virtual network fu

The indigestible fraction (IF) isolated from three lunch menus: Modified Mexican Lunch (MM-L), Traditional Mexican Lunch (TM-L) and Alternative Mexican Lunch (AM-L), was studied in terms of antioxidant capacity (AOX) and metabolites produced through fermentation by human intestinal microbiota. IFs were isolated after withstanding in vitro gastrointestinal digestion and total soluble polyphenols (T

The atomic structure of the cubic-SiC(001) surface during ultra-high vacuum graphene synthesis has been studied using scanning tunneling microscopy (STM) and low-energy electron diffraction. Atomically resolved STM studies prove the synthesis of a uniform, millimeter-scale graphene overlayer consisting of nanodomains rotated by +/- 13.5 degrees relative to the < 110 >-directed boundaries. The pref

Accelerated cell aging, indexed in peripheral leukocytes by telomere shortness and in peripheral blood mononuclear cells (PBMCs) by telomerase activity, has been reported in several studies of major depressive disorder (MDD). However, the relevance of these peripheral measures for brain indices that are presumably more directly related to MDD pathophysiology is unknown. In this study, we explored

Background: Calcitonin gene-related peptide (CGRP) release from trigeminal structures is central to migraine pathophysiology. This study employed an ex vivo model preserving anatomical continuity between the trigeminal nucleus caudalis (TNC) and trigeminal ganglion (TG) to investigate (1) whether TNC stimulation induces peripheral CGRP release from the TG and (2) the potential involvement of a dis

Background Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-S), (together DHEA[S]), are the most abundant adrenal steroids in humans and are found in blood and the brain, where they function as neurosteroids with direct receptor affinities. Preclinical studies suggest that DHEA(S) has antidepressant/neuroprotective properties, and exogenously administered DHEA has shown anti

During an infection, the genetic composition of the pathogen population in the host might range from clonal to genetically diverse, depending on the genetic variation of the inoculum, mutation events, genetic drift, and host selection during the course of the infection. Variation in the genetic diversity of avian malaria parasites, both within and between individual hosts, is not well documented.

Despite current therapies, there remains an unmet need for treatment for patients with hemophilia. The main parts of two phase 2 trials established clinical proof-of-concept for once-daily, subcutaneous concizumab prophylaxis in patients with hemophilia A/B with inhibitors (HAwI/HBwI; explorer4) and severe hemophilia A without inhibitors (HA; explorer5). Here, we present results from extension par

Purpose: It has been suggested that cysteine-rich secretory protein 3 (CRISP-3) and p-microseminoprotein (MSP) are associated with outcome in prostate cancer. We investigated whether these markers are related to biochemical recurrence and whether addition of the markers improves prediction of recurring disease. Experimental Design: Tissue microarrays of radical prostatectomy specimens were analyze

A variational Bayesian EM with smoothed probabilities algorithm for hidden Markov trees (HMT) is proposed for incomplete tree structured data. The full posterior of the HMT parameters is determined and the underflow problems associated with previous algorithms are eliminated. Example results for the prediction of the types of cells in real stem cell lineage trees are presented.

The “neurotrophic hypothesis of depression” posits that low levels of brain-derived neurotrophic factor (BDNF) are associated with Major Depressive Disorder (MDD). Low levels of BDNF have also been found in individuals with suicide attempts, in MDD or other disorders, suggesting that low BDNF may also be associated with suicidality. We assessed serum BDNF in 68 physically healthy and unmedicated (

Preclinical and genetic studies suggest that impaired glucose-dependent insulinotropic polypeptide receptor (GIPR) signaling worsens glycemic control. The relationship between GIPR signaling and the risk of cancers influenced by impaired glucose homeostasis is unclear. We examined the association of a variant in GIPR, rs1800437 (E354Q), shown to impair long-term GIPR signaling and lower circulatin

Introduction: The current standard method for breast cancer screening is digital mammography (DM). Digital breast tomosynthesis (DBT) can detect more cancers but is more resource-demanding, not the least due to a more time-consuming reading, which hinders the implementation in screening. Artificial intelligence (AI) might open possibilities to overcome this, but different potential ways of using A

Background: Analysis of how digital breast tomosynthesis (DBT) screening affects consecutive screening performance is important to estimate its future value in screening. Purpose: To evaluate whether DBT contributes to early detection of breast cancer by assessing cancer detection rates (CDRs), including the fraction of invasive cancers and cancer subtypes in consecutive routine digital mammograph

The purpose of this study was to investigate the effect of moisture on the heat transfer through clothing in relation to the water vapour resistance, type of underwear, location of the moisture and climate. This forms part of the work performed for work package 2 of the European Union THERMPROTECT project. Thermal manikin results of dry and wet heat loss are presented from different laboratories f

Disease-modifying therapies (DMTs) for multiple sclerosis (MS) can increase the risk of hepatitis B virus (HBV) reactivation (HBr), particularly with agents like ocrelizumab and alemtuzumab. However, studies in MS patients treated with DMTs indicate significantly lower reactivation rates compared to those with hematologic malignancies. This review discusses strategies for managing HBV in MS patien