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Comparing 3 Dietary Pattern Methods-Cluster Analysis, Factor Analysis, and Index Analysis-With Colorectal Cancer Risk

The authors compared dietary pattern methods-cluster analysis, factor analysis, and index analysis-with colorectal cancer risk in the National Institutes of Health (NIH)-AARP Diet and Health Study (n = 492,306). Data from a 124-item food frequency questionnaire (1995-1996) were used to identify 4 clusters for men (3 clusters for women), 3 factors, and 4 indexes. Comparisons were made with adjusted

Switching treatments in haemophilia: is there a risk of inhibitor development?

Patients with haemophilia A (and their physicians) may be reluctant to switch factor VIII (FVIII) concentrates, often due to concerns about increasing the risk of inhibitors; this reluctance to switch may contribute to patients missing the clinical benefits provided by the arrival of new factor VIII products. This topic was explored at the Eleventh Zurich Haemophilia Forum. Clinical scenarios for

Sociology and the New Institutionalism

In sociology, new institutionalists led the revival in interest in institutions in organizational theory and economic sociology by shifting the focus of causal reasoning from agent-centric studies of economic and organizational actors to the relationship connecting the firm with its institutional environment. We suggest a multilevel causal model incorporating the connection between the subinstitut

In vitro colonic fermentation of food ingredients isolated from Agave tequilana Weber var. azul applied on granola bars

The stem of Agave tequilana Weber is used to obtain fructans. Reports on the potential prebiotic activity of agave fructans as ingredients are scarce. The aim of this study was to evaluate the indigestible fraction (IF) content and the short chain fatty acid production (SCFA) from in vitro fermentation of: Native-agavefructans (NAF), agave-dietary-fiber (ADF), high-performance-fructans (HPF), both

On the self-assembly of a tryptophan labeled deoxycholic acid

Self-assembly of peptides and bile acids has been widely investigated because of their biological role and their potential as a tool for the preparation of nanostructured biomaterials. We herein report both the synthesis and the self-association behavior of a compound that combines the aggregation properties of bile acid- and amino acid-based molecules. The derivative has been prepared by introduc

On SAGBI bases and resultants

A resultant-type identity for univariate polynomials is proved and applied to characterization of SAGBI bases of subalgebras, generated by two polynomials. Besides a new condition for polynomials f(x) and g(x) to form a SAGBI basis, expressed in terms of field extensions is derived.

Hydrodynamic trapping of molecules in lipid bilayers

In this work we show how hydrodynamic forces can be used to locally trap molecules in a supported lipid bilayer (SLB). The method uses the hydrodynamic drag forces arising from a flow through a conical pipette with a tip radius of 1-1.5 mu m, placed approximately 1 mu m above the investigated SLB. This results in a localized force-field that acts on molecules protruding from the SLB, yielding a hy

Approximate solution of boundary integral equations for biharmonic problems in non-smooth domains

This paper deals with approximate solutions to integral equations arising in boundary value problems for the biharmonic equation in simply connected piecewise smooth domains. The approximation method considered demonstrates excellent convergence even in the case of boundary conditions discontinuous at corner points. In an application we obtain very accurate approximations for some characteristics

The COMBS Survey - III. The chemodynamical origins of metal-poor bulge stars

The characteristics of the stellar populations in the Galactic bulge info and constrain the Milky Way's foation and evolution. The metal-poor population is particularly important in light of cosmological silations, which predict that some of the oldest stars in the Galaxy now reside in its centre. The metal-poor bulge appears to consist of ltiple stellar populations that require dynamical analyses

Evaluation of soil carbon dynamics after forest cover change in CMIP6 land models using chronosequences

Land surface models are used to provide global estimates of soil organic carbon (SOC) changes after past and future change land use change (LUC), in particular re-/deforestation. To evaluate how well the models capture decadal-scale changes in SOC after LUC, we provide the first consistent comparison of simulated time series of LUC by six land models all of which participated in the coupled model

The role of hand-held ultrasound for cardiopulmonary assessment during a pandemic

During the COVID-19 pandemic, we are likely to see a significant increase in the requests for rapid assessment of cardiac function, due to the frequent pre-existence of cardiac pathologies in patients admitted to hospital, and to the emergence of specific cardiac manifestations of this infection, such as myocarditis, sepsis related cardiomyopathy, stress induced cardiomyopathy and acute coronary s

Wafer-scale nanofabrication of sub-100 nm arrays by deep-UV displacement Talbot lithography

In this manuscript, we demonstrate the potential of replacing the standard bottom anti-reflective coating (BARC) with a polymethylglutarimide (PMGI) layer for wafer-scale nanofabrication by means of deep-UV displacement talbot lithography (DTL). PMGI is functioning as a developable non-UV sensitive bottom anti-reflective coating (DBARC). After introducing the fabrication process using a standard B

Modeling to Predict Factor VIII Levels Associated with Zero Bleeds in Patients with Severe Hemophilia A Initiated on Tertiary Prophylaxis

Background: Factor VIII (FVIII) trough levels > 1 IU/dL in patients with severe hemophilia A receiving regular prophylaxis may optimize bleed protection. Objectives: In this post hoc analysis of patients receiving tertiary prophylaxis for approximately 1 year, the relationship between estimated FVIII levels and reported bleeds was investigated to predict the potential for zero bleeds. Methods: Six

Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis

The causal association of NUDT1 (=MTH1) and OGG1 with hereditary colorectal cancer (CRC) remains unclear. Here, we sought to provide additional evidence for or against the causal contribution of NUDT1 and OGG1 mutations to hereditary CRC and/or polyposis. Mutational screening was performed using pooled DNA amplification and targeted next-generation sequencing in 529 families (441 uncharacterized M

Swiss pendling hammer for decoupling measurement of Swiss methodology for decoupling measurement of service equipment in buildings

The latest edition of the Swiss standard SIA181(2006) Protection against noise in Buildings [1], introduces a new methodology regarding the tests to be performed in new constructions for noise induced by human using service equipment in bathroom and kitchen. In this method, a specific pendling hammer has been developed especially for evaluating the decoupling efficiency of service equipment. The g

On the Error-Correcting Capabilities of Low-Complexity Decoded LDPC Codes with Constituent Hamming Codes

Hamming code-based LDPC (H-LDPC) block codes are obtained by replacing the single parity-check constituent codes in Gallager's LDPC codes with Hamming codes. This paper investigates the asymptotic performance of ensembles of random H-LDPC codes, used over the binary symmetric channel and decoded with a low-complexity hard-decision iterative decoding algorithm. It is shown that there exist H-LDPC c

Application of Py-GC/MS coupled with PARAFAC2 and PLS-DA to study fast pyrolysis of genetically engineered poplars

Field-grown genetically engineered and wild-type poplars were pyrolyzed in a micro-pyrolysis (Py-GC/MS) setup under fast pyrolysis conditions. Poplars (Populus tremula x P. alba) down-regulated for cinnamoyl-CoA reductase (CCR), which catalyzes the first step of the monolignol-specific branch of the phenylpropanoid biosynthetic pathway, were grown in field trials in France and harvested after a fu

Management of Arrhythmias and Cardiac Implantable Electronic Devices in Patients With Left Ventricular Assist Devices

For patients with end-stage heart failure, the use of mechanical circulatory support has increased in the last decade due to improved outcomes with durable left ventricular assist devices. The management of these complex patients requires coordinated care by a multidisciplinary team including cardiac electrophysiologists because atrial and ventricular arrhythmias are prevalent in this population.