A genome-wide study performed in a Japanese population identified a strong association between SNP rs2294008 (Met1Thr) in the Prostate Stem Cell Antigen gene (PSCA) and diffuse-type gastric cancer (GC). This association was validated in different Asian populations, and, very recently, a study has been published in Caucasians. In this study, we analyzed the association between PSCA variation and GC

Type 2 diabetes (T2D) is a complex metabolic disease associated with obesity, insulin resistance and hypoinsulinemia due to pancreatic β-cell dysfunction. Reduced mitochondrial function is thought to be central to β-cell dysfunction. Mitochondrial dysfunction and reduced insulin secretion are also observed in β-cells of humans with the most common human genetic disorder, Down syndrome (DS, Trisomy

Background: Intraductal papillary neoplasm of the bile ducts (IPNB) is a rare disease in Western countries. The aim of this study was to compare tumor characteristics, management strategies, and outcomes between Western and Eastern patients who underwent surgical resection for IPNB. Methods: A multi-institutional retrospective series of patients with IPNB undergoing surgery between January 2010 an

We present a catalog of stellar properties for a large sample of 6676 evolved stars with Apache Point Observatory Galactic Evolution Experiment spectroscopic parameters and Kepler asteroseismic data analyzed using five independent techniques. Our data include evolutionary state, surface gravity, mean density, mass, radius, age, and the spectroscopic and asteroseismic measurements used to derive th

The discovery of reliable biomarkers to predict efficacy and toxicity of anticancer drugs remains one of the key challenges in cancer research. Despite its relevance, no efficient study designs to identify promising candidate biomarkers have been established. This has led to the proliferation of a myriad of exploratory studies using dissimilar strategies, most of which fail to identify any promisi

The interaction of two confined coaxial jets has been studied using Computational Fluid Dynamics. Annular jet flows over 8 flat blade swirl generator. Numerical simulation uses RNG k- ϵ turbulence model. These models are suitable for turbulent swirl dominated flows. Intermediate swirl injector has been simulated and the flow patterns for non-reactive and reactive cases are contrasted. Low swirling

The mass of a star is the most fundamental parameter for its structure, evolution, and final fate. It is particularly important for any kind of stellar archaeology and characterization of exoplanets. There exist a variety of methods in astronomy to estimate or determine it. In this review we present a significant number of such methods, beginning with the most direct and model-independent approach

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Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons cells Article Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons Jessica Giacomoni 1, Andreas Bruzelius 2 , Christina-Anastasia Stamouli 2 and Daniella Rylander Ottosson 2,* 1 Group of Developmental and Regenerative Neurobiology, Wallenberg Neuroscience Cente

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All Charter Valid Erasmus code Application Reference Number PIC Application Country Code Name of the organisation Organisation Address Organisation Postal Code Organisation City Organisation Country Name ECHE Validity A BADEN01 28505-EPP-1-2014-1-AT-EPPKA3-ECHE 948821603 AT PAEDAGOGISCHE HOCHSCHULE NIEDERÖSTERREICH MÜHLGASSE 67 2500 BADEN Austria 12/31/2023 A DORNBIR01 29270-EPP-1-2014-1-AT-EPPKA3

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