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Andreas Nilsson

Universitetslektor Kontaktinformation E-post: andreas [dot] nilsson [at] mgeo [dot] lu [dot] seOrganisation Miljö- och geovetenskapliga institutionen (MGeo) Hämtställe: 16 WebbplatsAndreas Nilssons profil i Lunds universitets forskningsportalAndra roller Universitetslektor Geologiska institutionenResearchThe Earth's magnetic field is generated by fluid motions in the outer core (the geodynamo). Th

https://www.geologi.lu.se/andreas-nilsson - 2026-05-06

Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts

Background: Complement is an important mediator in arterial blood pressure-induced vein graft failure. Previously, we noted activation of cell protective mechanisms in human saphenous veins too. Here we have analyzed whether C4b-binding protein (C4bp), an endogenous complement inhibitor, is present in the vein wall. Methods: Human saphenous vein segments obtained from patients undergoing coronary

Theoretical simulations of oxygen K -edge resonant inelastic x-ray scattering of kaolinite

Near-edge x-ray absorption fine structure (NEXAFS) and resonant inelastic x-ray scattering (RIXS) measurements at the oxygen K edge were combined with theoretical spectrum simulations, based on periodic density functional theory and nuclear quantum dynamics, to investigate the electronic structure and chemical bonding in kaolinite Al2Si2O5(OH)4. We simulated NEXAFS spectra of all crystallographica

Simulation of two-phase flow in a heat exchanger distributor application

In this work, compulations of the air/water flow in a distributor were completed with the FLUENT two-phase VOF model and compared to experiments. The parameters of interest concerned the ratio between the deflected mass flow rate of the water phase to the mass flow rate of the water phase at the inlet called the deflection ratio as well as the recreation of the flow pattern of the different two-ph

Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation.

Inhibitory CD33-related Siglec receptors regulate immune cell activation upon engaging ubiquitous sialic acids (Sias) on host cell surface glycans. Through molecular mimicry, Sia-expressing pathogen group B Streptococcus binds inhibitory human Siglec-9 (hSiglec-9) to blunt neutrophil activation and promote bacterial survival. We unexpectedly discovered that hSiglec-9 also specifically binds high m

Design of low order approximately linear phase IIR filters

In this paper, a new method for the design of approximately linear phase IIR filters is proposed. This method is based on first designing an asymmetrical FIR filter which is approximately linear phase and then deriving a low order approximately linear phase IIR filter by model reduction techniques.

Priors and Posteriors in Bayesian Timing of Divergence Analyses : The Age of Butterflies Revisited

The need for robust estimates of times of divergence is essential for downstream analyses, yet assessing this robustness is still rare. We generated a time-calibrated genus-level phylogeny of butterflies (Papilionoidea), including 994 taxa, up to 10 gene fragments and an unprecedented set of 12 fossils and 10 host-plant node calibration points. We compared marginal priors and posterior distributio

Non-Invasive Monitoring of Architectural Heritage

Popular Abstract in Swedish Två mobila system, ett svenskt och ett italienskt, för undersökning av historiska fasader har använts för att undersöka möjligheten till identifiering av olika material, biologisk påväxt och faktorer som i framtiden kan leda till nedbrytning av kulturhistoriskt värdefulla monument. Undersökningarna visade på möjligheter att genomföra analyser av ytor med hjälp av fluoreThe on-site documentation and examination of architectural heritage has presented challenges for traditional analysis methods in the form of, among other things, large complex structures, sites and environmental conditions. In recent years there has been growing interest in assessing progressing deterioration processes and material analysis, with an emphasis on sustainable conservation and mainten

Osteopontin affects insulin vesicle localization and Ca2+ homeostasis in pancreatic beta cells from female mice

Type 2 diabetic patients suffer from insulin resistance and reduced insulin secretion. Osteopontin (OPN), a versatile protein expressed in several tissues throughout the body including the islets of Langerhans, has previously been implicated in the development of insulin resistance. Here we have investigated the role of OPN in insulin secretion using an OPN knock out mouse model (OPN-/-). Ultra-st

The effect of forest owner decision-making, climatic change and societal demands on land-use change and ecosystem service provision in Sweden

The uncertain effects of climatic change and changing demands for ecosystem services on the distribution of forests and their levels of service provision require assessments of future land-use change, ecosystem service provision, and how ecosystem service demands may be met. We present CRAFTY-Sweden, an agent-based, land-use model that incorporates land owner behaviour and decision-making in model

pH Sensitive Tubules of a Bile Acid Derivative: a Tubule Opening by Release of Wall Leaves

Tubules formed by self-assembly of organic molecules have a vast potential in nanotechnology applications and the introduction of sensitivity to stimuli into self-assembly tubules represents a particularly attractive feature. Here we report on the preparation and characterization of a molecule obtained by chemical modification of a natural bile acid, a biological surfactant, that self-assembles in

Our journey toward implementation of digital breast tomosynthesis in breast cancer screening : the Malmö Breast Tomosynthesis Screening Project

Purpose: The purpose is to describe the Malmö Breast Tomosynthesis Screening Project from the beginning to where we are now, and thoughts for the future. Approach: In two acts, we describe the efforts made by our research group to improve breast cancer screening by introducing digital breast tomosynthesis (DBT), all the way from initial studies to a large prospective population-based screening tri

Association between injury-related factors and cartilage T2 relaxation time in the subacute phase in patients after anterior cruciate ligament injury

OBJECTIVE: To investigate associations between meniscal tear, bone marrow lesions (BMLs), and post-injury knee loading, with cartilage T2 relaxation times on knee magnetic resonance imaging (MRI) in the subacute phase following acute anterior cruciate ligament (ACL) injury.DESIGN: We studied both knees of 128 patients with ACL injury. The presence of meniscal tears and BMLs were determined on suba

BAY 81-8973 Demonstrates Long-Term Safety and Efficacy in Children With Severe Haemophilia A : Results From the LEOPOLD Kids Extension Study

OBJECTIVES: To report the long-term safety and efficacy of BAY 81-8973 in the LEOPOLD Kids extension phase.METHODS: Patients received BAY 81-8973 (25-50 IU/kg) at least twice weekly. The primary endpoint was safety, assessed in all patients who entered the extension phase (n = 82). Efficacy endpoints were assessed in patients without high-titre inhibitors/immune tolerance induction (n = 67).RESULT

Development of Training Materials for Pathologists to Provide Machine Learning Validation Data of Tumor-Infiltrating Lymphocytes in Breast Cancer

The High Throughput Truthing project aims to develop a dataset for validating artificial intelligence and machine learning models (AI/ML) fit for regulatory purposes. The context of this AI/ML validation dataset is the reporting of stromal tumor-infiltrating lymphocytes (sTILs) density evaluations in hematoxylin and eosin-stained invasive breast cancer biopsy specimens. After completing the pilot

Progesterone distribution in the trigeminal system and its role to modulate sensory neurotransmission : influence of sex

Background: Women are disproportionately affected by migraine, representing up to 75% of all migraine cases. This discrepancy has been proposed to be influenced by differences in hormone levels between the sexes. One such hormone is progesterone. Calcitonin gene-related peptide (CGRP) system is an important factor in migraine pathophysiology and could be influenced by circulating hormones. The pur

Galiellalactone is a Direct Inhibitor of STAT3 in Prostate Cancer Cells.

The transcription factor STAT3 is constitutively active in several malignancies including castration-resistant prostate cancer and has been identified as a promising therapeutic target. The fungal metabolite galiellalactone, a STAT3 signaling inhibitor, inhibits the growth, both in vitro and in vivo, of prostate cancer cells expressing active STAT3 and induces apoptosis of prostate cancer stem cel