Sökresultat

Background: The secreted enzyme EndoS, an endoglycosidase from Streptococcus pyogenes, hydrolyzes the N-linked glycan of the constant region of immunoglobulin G (IgG) heavy chain and renders the antibody unable to interact with Fc receptors and elicit effector functions. In this study we couple targeted allelic replacement mutagenesis and heterologous expression to elucidate the contribution of En

A parsimonious set of mechanisms explains how and under which conditions behavioral deviations build into cascades that reshape institutional frameworks from the bottom up, even if institutional innovations initially conflict with the legally codified rules of the game. Specifically, we argue that this type of endogenous institutional change emerges from an interplay between three factors: the uti

This article traces the reception of the the Swedish film Ingeborg Holm in 1913. The film created a fierce debate regarding the Swedish poor laws. This debate eventually led to changes in the law in 1918.

We report a case of a 5-year-old child who suffered an oral allergy syndrome and lip angiedema after eating grapes. We obtained a positive prick test with commercial grape extract and a positive prick-by-prick test with pulp and peel of fresh white grape (Moscatel variety) and pulp and peel of blue grape. Sodium dodecyl sulphate-polyacrylamide gel electrophoresis followed by immunoblotting reveale

We purified a laccase isoenzyme, Lad 1 from Galerina sp. HC1 using a combination of anion exchange- and hydrophobic interaction chromatography. Lad l has a molecular mass of 64 kDa, an isoelectric point of 4, and 3.35 copper atoms/enzyme molecule. The enzyme has features typical of fungal blue laccases. The sequences of two internal peptides were highly similar to reported laccase sequences from o

Modification of the resonance fluorescence spectrum of a two-level atom driven by a monochromatic field in the close proximity of a plasmonic nanostructure (metal sphere) is studied in detail. It is shown that one can control this spectrum by varying several key parameters: (i) the radius of the nanosphere, (ii) polarization of the incident radiation, and (iii) the atom's location around the nanos

This study reports findings from the first large-scale experiment investigating whether entrepreneurs differ 1 from other people in their willingness to expose themselves to various forms of uncertainty. A stratified random sample of 700 chief executive officers from the Yangzi delta region in China is compared to 200 control group members. Our findings suggest that in economic decisions, entrepre

Mixed species charge and baryon balance functions are computed based on proton-proton (pp) collisions simulated with the PYTHIA8 model. Simulations are performed with selected values of the collision energy s and the Monash tune and the ropes and shoving modes of PYTHIA8 to explore whether such measurements provide useful new information and constraints on mechanisms of particle production in pp c

Detta examensarbete undersöker hur svenska banker kommunicerar och marknadsför gröna lån, samt i vilken utsträckning denna kommunikation riskerar att bidra till greenwashing, när företag ger en bild av att vara mer miljövänliga än vad som är fallet. Studien utgår från en kvalitativ metod och baseras på intervjuer med tre svenska banker, Swedbank, SEB och Sparbanken Skåne samt tre fastighetsbolag, This thesis investigates how Swedish banks communicate and market green loans, and to what extent this communication risks contributing to greenwashing, when companies portray themselves as more environmentally friendly than they actually are. The study employs a qualitative method and is based on interviews with three Swedish banks, Swedbank, SEB, and Sparbanken Skåne, as well as three real estat

Atmospheric aerosols contain organic molecules that serve as cloud condensation nucleation sites and affect the climate. Several experimental and simulation studies have been dedicated to investigate their surface propensity, but the mechanisms that drive them to the water surface are still not fully understood. In this molecular dynamics (MD) simulation study, primary alcohols are considered as a

In this work, we investigate production of Drell-Yan (DY) pairs in proton-nucleus collisions in kinematic regions where the corresponding coherence length does not exceed the nuclear radius, RA, and the quantum coherence effects should be treated with special care. The results for the nucleus-to-nucleon production ratio available in the literature so far are usually based on the assumption of a ve

During the past years Enterprise 2.0 has become widely spread among organization. However is there not enough awareness in the organizations concerning the necessary organizational changes which companies need to address when planning for the shift to Enterprise 2.0. In this study we aim to indentify solutions for success which affect if an Enterprise 2.0 implementation will succeed or not and how

Migraines constitute a common neurological and headache disorder affecting around 15% of the world’s population. In addition to other mechanisms, neurogenic neuroinflammation has been proposed to play a part in migraine chronification, which includes peripheral and central sensitization. There is therefore considerable evidence suggesting that inflammation in the intracranial meninges could be a k

When Sweden entered NATO in 2024, 200 years of alliance-freedom was upheaved. Article 5 of the North Atlantic Treaty states that an attack on any of the allied states is to be considered an attack against them all, which means that Swedish soldiers may be deployed in combat on foreign soil. Given that the Swedish Armed Forces have previously only been concerned with protecting their own borders, t