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Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors ARTICLE Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors Marie E Jönsson1, Per Ludvik Brattås1, Charlotte Gustafsson2, Rebecca Petri1, David Yudovich3, Karolina Pircs1, Shana Verschuere1, Sofia Madsen1, Jenny Hansson 4, Jonas Larsson3,
Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9 ARTICLE Received 25 Jan 2013 | Accepted 26 Mar 2013 | Published 23 Apr 2013 Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9 Malin Åkerblom1,*, Rohit Sachdeva1,*, Luis Quintino2,*, Erika Elgstrand Wettergren2, Katie Z
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/akerblom1.pdf - 2025-06-08
Brain Plasticity 3 (2017/2018) 195–203 DOI 10.3233/BPL-180066 IOS Press 195 Review Crosstalk between MicroRNAs and Autophagy in Adult Neurogenesis: Implications for Neurodegenerative Disorders Karolina Pircs1, Rebecca Petri1 and Johan Jakobsson∗ Department of Experimental Medical Science, Laboratory of Molecular Neurogenetics, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund Universi
Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned? REVIEW published: 28 September 2017 doi: 10.3389/fnins.2017.00530 Frontiers in Neuroscience | www.frontiersin.org 1 September 2017 | Volume 11 | Article 530 Edited by: Kyle David Fink, University of California, Davis, United States Reviewed by: Jennifer Fifita, Macquarie University, Aust
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/fnins-11-00530.pdf - 2025-06-08
Microsoft Word - 68284559-file00 10.1101/gr.147678.112Access the most recent version at doi: published online December 10, 2012Genome Res. Helen M Rowe, Adamandia Kapopoulou, Andrea Corsinotti, et al. cells necessary to preserve transcriptional dynamics in embryonic stem TRIM28 repression of retrotransposon-based enhancers is P
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/full_article.pdf - 2025-06-08
Microsoft Word - MolCel4048mmc1_Revised.docx Molecular Cell, Volume 44 Supplemental Information In Embryonic Stem Cells, ZFP57/KAP1 Recognize a Methylated Hexanucleotide to Affect the Chromatin and DNA Methylation of Imprinting Control Regions Simon Quenneville, Gaetano Verde, Andrea Corsinotti, Adamandia Kapopoulou, Johan Jakobsson, Sandra Offner, Ilaria Baglivo, Paolo V. Pedone, Giovanna Grimald
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/jj.pdf - 2025-06-08
DEV122747 3166..3177 RESEARCH ARTICLE STEM CELLS AND REGENERATION Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor Marie E. Jönsson1,2, Jenny Nelander Wahlestedt2, Malin Åkerblom1, Agnete Kirkeby2, Josephine Malmevik1, Per Ludvik Brattaas1, Johan Jakobsson1,*,‡ and Malin Parmar2,*,‡ ABSTRACT MicroRNAs (miRNAs)
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/jonsson.pdf - 2025-06-08
pnas201105135 1..6 Direct conversion of human fibroblasts to dopaminergic neurons Ulrich Pfisterer1, Agnete Kirkeby1, Olof Torper1, James Wood, Jenny Nelander, Audrey Dufour, Anders Björklund, Olle Lindvall, Johan Jakobsson, and Malin Parmar2 Departments of Experimental Medical Science and Clinical Sciences, Wallenberg Neuroscience Center, and Lund Stem Cell Center, Lund University, SE-221 84 Lund
BioMed CentralBMC Biotechnology ss Open AcceResearch article Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants Troels T Nielsen1,2, Johan Jakobsson1, Nina Rosenqvist1 and Cecilia Lundberg*1 Address: 1CNS Gene Therapy Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Sciences, Lund University, BMC A11, S-221 84 Lund,
©2011 Landes Bioscience. Do not distribute. www.landesbioscience.com Cell Cycle 3421 Cell Cycle 10:20, 3421-3422; October 15, 2011; © 2011 Landes Bioscience EditOriaLs: CELL CyCLE FEaturEs EditOriaLs: CELL CyCLE FEaturEs A series of recent publications have shown that human fibroblasts can be directly converted to functional neurons using defined combinations of transcription factors.1-3 The resul
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_cell_cycle.pdf - 2025-06-08
REST suppression mediates neural conversion of adult human fibroblasts via microRNA‐dependent and ‐independent pathways Research Article REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways Janelle Drouin-Ouellet1,†, Shong Lau1,†, Per Ludvik Brattås1, Daniella Rylander Ottosson1, Karolina Pircs1, Daniela A Grassi1, Lucy M Collins2,
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_embo_mol_med.pdf - 2025-06-08
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Regulated Delivery of Glial Cell Line-Derived Neurotrophic Factor into Rat Striatum, Using a Tetracycline-Dependent Lentiviral Vector HUMAN GENE THERAPY 15:934–944 (October 2004) © Mary Ann Liebert, Inc. Regulated Delivery of Glial Cell Line-Derived Neurotrophic Factor into Rat Striatum, Using a Tetracycline-Dependent Lentiviral Vector BILJANA GEORGIEVSKA,* JOHAN JAKOBSSON,* ELISABETH PERSSON, CEC
Evidence for disease-regulated transgene expression in the brain with use of lentiviral vectors Evidence for Disease-Regulated Transgene Expression in the Brain With Use of Lentiviral Vectors Johan Jakobsson,1 Nina Rosenqvist,1 Karl Mårild,1 Denes v. Agoston,2 and Cecilia Lundberg1* 1Department of Experimental Medical Research, Section for Neuroscience, Wallenberg Neuroscience Centre, Lund Univer
465 Chapter 34 Using Endogenous MicroRNA Expression Patterns to Visualize Neural Differentiation of Human Pluripotent Stem Cells Agnete Kirkeby, Malin Parmar, and Johan Jakobsson Abstract Many existing protocols for neuronal differentiation of human pluripotent cells result in heterogeneous cell populations and unsynchronized differentiation, necessitating the development of methods for labeling s
