The role of CTCF and cohesin in high hyperdiploid childhood acute lymphoblastic leukemia
Chromosome defects in high hyperdiploid childhood acute lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is a type of blood cancer that affects both adults and children. While human cells normally harbor 46 chromosomes, the leukemic cells of the high hyperdiploid subgroup (HeH) of childhood ALL presents 51-67 chromosomes, where the extra chromosomes are generally X, 4, 6, 10, 14, 17, 18