We propose symmetrical cationic trimethine cyanine dyes with β-substituents in the polymethine chain based on modified benzothiazole and benzoxazole heterocycles as probes for the detection and visualization of live and fixed cells by fluorescence microscopy. The spectral-luminescent properties of trimethine cyanines have been characterized for free dyes and in the presence of nucleic acids (NA) a

In 2025, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health celebrates 75 years of leadership in diabetes research. The NIDDK serves people of the U.S. affected by or at risk for many chronic diseases, including diabetes and other endocrine, metabolic, and digestive disorders, by funding innovative research to develop better treatment

Vegetation is the major source of volatile organic compounds (VOCs) in the atmosphere, which affect both air quality and climate. Long-term ecosystem-level data on biogenic VOC (BVOC) emissions, however, are limited. This is especially true regarding the impacts of landscape-scale disturbances like clear-cutting on the short-term and longer seasonal-scale emissions of boreal forests, particularly

Overview: Prostate cancer (PC)is the most common cancer in Sweden, and the leading cause of cancer death. Positronemission tomography with x-ray computed tomography (PET/CT) is an important imagingmethod for many cancers. A group of PET radiopharmaceuticals known as PSMA(prostate specific membrane antigen) ligands has been introduced for imaging ofPC. This thesis investigates aspects of the ligand

Under slutet av 1900-talet var den svenska reformtakten hög vilket gjorde ekonomin konkurrenskraftig och att Sverige klarade finanskrisen 2008–2010 bättre än jämförbara länder. Nu har reformtakten avtagit och den ekonomiska friheten är fallande på flera områden. I en ny rapport från Entreprenörskapsforum konstateras att 2010-talet blev ett i allt väsentligt förlorat decennium med minskad ekonomisk

Denna artikel behandlar fyndet av en kota från en bardval som påträffades under utgrävningarna av Västra Karaby, en vendeltida boplats i västra Skåne. Fynd av bardvalar i skånska järnåldersboplatser är mycket sällsynta. I artikeln diskuteras kotans proveniens, kronologiska tillhörighet och betydelse för förståelsen av boplatsen. En taxonomisk bestämning av kotan har gjorts genom den benkemiska pep

Bimetallic nanoparticles exhibit unique physicochemical characteristics that often translateinto functional properties surpassing those of their monometallic counterparts. The abilityto precisely tailor these characteristics enables fine-tuning of their properties for targetedapplications. This doctoral thesis investigates the engineering of bimetallic nanoparticlesvia spark ablation, a continuous

Quasi-markets in the provision of public services are increasingly common but also highly contested. We formulate a conceptual framework based on economic theory to describe how quasi-markets differ from traditional markets in five aspects: 1) revenues, costs, and profits; 2) the matching of supply and demand; 3) competition; 4) structural change; and 5) rent-seeking. Using the assumption of profi

Neuroendocrine tumours (NETs) of the small intestine (siNET) are slow-growing malignancies often diagnosed at an advanced stage. Despite their indolent nature, patients frequently experience significant symptoms, including carcinoid syndrome (CS) with diarrhoea, which impact their health-related quality of life (HRQoL). This thesis investigates the determinants of HRQoL in siNET patients, its prog

Recension av Daniel Pedersen, Natt och aska – Förintelsens litteratur.

Atrial fibrillation (AF) is common condition among the elderly, and leads toincreased risks of stroke, heart failure, dementia, and death. Diagnosing AF requires electrocardiograms (ECGs), and long recordings may be necessary since AF often occurs intermittently in its early stages. During AF, the heart rate is irregular, and sometimes inappropriately fast. This thesis includes four papers that st

The purpose of this thesis is to investigate different scales of mobility and social networks in Southern Scandinavia around 7000 BC. An essential basis for this work is the hypothesis that the conical core pressure blade technology, a specific method for producing lithic blades, reached Scandinavia from the east. The process has been discussed and verified in several earlier studies.The study is The purpose of this thesis is to investigate different scales of mobility and social networks in Southern Scandinavia around 7000 BC. An essential basis for this work is the hypothesis that the conical core pressure blade technology, a specific method for producing lithic blades, reached Scandinavia from the east. The process has been discussed and verified in several earlier studies.The study is

Muscle-invasive bladder cancer (MIBC) is characterised by significant molecular heterogeneity, with the tumour composition being further sculptured by local microenvironmental influences. This inherent complexity contributes to the divergent disease trajectories and the variable therapeutic susceptibility observed among patients. Consequently, there is an evident need for prognostic and predictive

Background: Adult hip dysplasia is one of the few potentially modifiable risk factors for hip osteoarthritis (OA). However, the prevalence of hip dysplasia and the strength of its association with OA are not fullyunderstood.Aims and methods:I. To determine the prevalence of hip dysplasia in a Swedish population and investigate whether the condition was mentioned in radiology reports. The center ed

Bioenergi spelar idag en stor roll i det svenska energisystemet ur klimat- och energisäkerhetssynpunkt men vilken roll kan inhemsk bioenergi komma att spela framöver för att Sverige ska bli ett fossilfritt samhälle med nettonollutsläpp 2050? Syftet med denna rapport är att utifrån olika perspektiv beskriva hur tillförseln av inhemska skogsbaserade biobränslen kan komma att förändras under perioden

With the rapid process of urbanization, water conflicts between different water use industries and areas are increasing. Therefore, China has implemented the three-cordons system of water resources management since 2012, when how to make more reasonable regulation of water resources became an urgent problem in most areas of China. In this study, taking the Yuanhe River Basin as an example, an inte