Introducing a hole in a glued laminated timber (glulam) beam generally results in a significant decrease in load bearing capacity. Global strength is most often limited by perpendicular to grain fracture with crack initiation at hole periphery and crack propagation in the grain direction. Strength analysis and design is far from trivial, which is reflected by the lack of design criteria in contemp

Empowering interventions can improve person-centered care. A pre- and post-evaluation using interactive research involving two years of empowering interventions was designed to improve quality of care in outpatients with chronic kidney disease who were pre-dialysis. The results showed significantly increased empowerment in the intervention group. Interactive research facilitated the implementation

This article adds empirical depth to our understanding of seniors’ involvement in the making of eHealth systems. Multi-sited interviews and observations were conducted at seniors’ homes before an eHealth system was installed, during the home trials and post-removal of the system. Our findings indicate that although the senior participants chose to participate in the home trials, the choice itself

Understanding species’ historical ranges can provide important information for conservation planning in the face of environmental change. Cromsigt et al. (this issue) comment on our recent European bison (Bison bonasus) range reconstruction, suggesting that bison were already 8000 years ago a refugee species (i.e. restricted to marginal habitat due to past human pressure) and that species distribu

We have synthesized hematite cube-shaped nanoparticles using different synthesis paths to examine the effect of the intermediate product akaganeite (beta-FeOOH) on the size and shape of the final hematite particles. Akaganeite spindles and hematite nanocubes are prepared using forced hydrolysis of iron chloride (FeCI3) salt. We use a combination of transmission electron microscopy (TEM), high reso

Aims alpha(1)-Antitrypsin (AAT) is a serine protease inhibitor which recently has been shown to prevent Type 1 diabetes development, to prolong islet allograft survival and to inhibit pancreatic B-cell apoptosis in vivo. It has also been reported that Type 1 diabetic patients have significantly lower plasma concentrations of AAT, suggesting the potential role of AAT in the pathogenesis of Type 1 d

The field of nanoscale thermoelectrics began with a clear motivation for better performances of waste heat recovery processes by lowering the system dimensionality. Although this original inspiration still drives many recent developments, the field has also evolved to address fundamental questions on charge and energy transport across quantum conductors in the presence of both voltage and temperat

A translation with religio-historical commentary from mediaeval Hebrew into Swedish of Moses Maimonides' chapters on the coming of the Messiah.

We present a novel method for measuring interbilayer forces in lamellar liquid crystals of amphiphile-water systems. In a centrifuge the gravitational effect is easily strong enough to produce clearly observable concentration gradients. During the experiment the concentration profile in the test-tube is monitored using NMR imaging of the deuterium quadrupole splitting in the lamellar phase, by tem

To model human neural-cell-fate specification and to provide cells for regenerative therapies, we have developed a method to generate human neural progenitors and neurons from human embryonic stem cells, which recapitulates human fetal brain development. Through the addition of a small molecule that activates canonical WNT signaling, we induced rapid and efficient dose-dependent specification of r

Background: Exposure to ambient air particulate matter (PM) has been linked to decline in pulmonary function and cardiovascular events possibly through inflammation. Little is known about individual exposure to ultrafine particles (UFP) inside and outside modern homes and associated health-related effects. Methods: Associations between vascular and lung function, inflammation markers and exposure

Thermal manikins are useful tools to study the clothing comfort and environmental ergonomics. The simulation of sweating can be achieved by putting a highly wicking stretchable knit fabric “skin” on top of the manikin. However, the addition of such a fabric skin makes it is difficult to accurately measure the skin surface temperature. Moreover, it takes considerable amount of time to measure the f

This thesis concerns the role of disability and assistive devices in everyday life among persons with, for instance, impairments related to mobility (e.g. wheelchair users) and bodily shape and configuration (e.g. dysmelia). Assistive devices are seen as both includators (assisting participation and emancipation) and excludators (limiting participation, restraining empowerment, and stigmatizing).

In the title compound, [Re(3)(mu-H)(3)(C(25)H(22)P(2))(CO)(10)]center dot CH(2)Cl(2), the three Re atoms form a triangle bearing ten terminal carbonyl groups and three edge-bridging hydrides. The bis(diphenylphosphanyl) methane ligand bridges two Re atoms. Neglecting the Re-Re interactions, each Re atom is in a slightly distorted octahedral coordination environment. The dichloromethane solvent mol

The fatigue crack propagation rate is influenced by various mechanisms at the very vicinity of the crack tip, e.g., local plasticity and/or creep, microcracking, crack branching, and crack closure induced by plasticity and roughness. To study these mechanisms and their influence on crack propagation rate during different loadings, in situ scanning electron microscope studies have been performed. T

Every year, approximately 1 million new colorectal cancer (CRC) cases are diagnosed and about half a million people worldwide die due to this cancer. Known differences in CRC incidence rates are mainly attributed to differences in diet and other environmental factors represented, among others, by nutrition-related complex diseases (e.g. obesity and diabetes mellitus type II). Within the last years

BACKGROUND: Exposure to perfluorooctane sulfonate (PFOS) may potentially disturb fetal Leydig cell hormone production and male genital development. OBJECTIVES: We aimed to study the associations between levels of amniotic fluid PFOS, fetal steroid hormone, and insulin-like factor 3 (INSL3) and the prevalence of cryptorchidism and hypospadias. METHODS: Using the Danish National Patient Registry, we