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Bacterial complement evasion strategies

As a first line of defense against pathogens and a mediator between innate and adaptive immunity, complement is a particular focus of evasion strategies developed by pathogens.  We showed that one common strategy is to bind complement inhibitor C4BP, which leads to decreased opsonisation of bacteria with C3b impairing phagocytosis and allowing bacterial survival. It appears that binding of C4BP is

https://www.protein-chemistry.lu.se/projects/bacterial-complement-evasion-strategies - 2025-05-03

Pathologic complement activation in diseases

  Myriam Martin, Rebecca Trattner and Anna Blom Misguided or excessive complement activation is involved in many common diseases such as rheumatoid arthritis, systemic lupus erythematosus, vasculitis and age-related macula degeneration. In collaboration with clinicians we are studying molecular mechanisms of complement involvement in these diseases. Joint inflammation in rheumatoid arthritis (RA),

https://www.protein-chemistry.lu.se/projects/pathologic-complement-activation-diseases - 2025-05-03

Complement and cancer

Expression of COMP in breast cancer tissue Complement-dependent cytotoxicity is one of the mechanisms by which therapeutic monoclonal antibodies are toxic to cancer cells. Also, complement is currently undergoing re-appreciation of its role in the immune surveillance of tumors. The majority of human tumors are low immunogenic and complement may be involved in their recognition via direct “danger s

https://www.protein-chemistry.lu.se/projects/complement-and-cancer - 2025-05-03

Inherited deficiencies of complement inhibitors

Complement has recently gained substantial worldwide attention, as it was discovered that several common diseases such as age-related macular degeneration (blindness in elderly) are related to deregulation of the balance between complement activation and inhibition. Full complement deficiencies lead to severe infectious and autoimmune diseases but are uncommon while it appears that we are just beg

https://www.protein-chemistry.lu.se/projects/inherited-deficiencies-complement-inhibitors - 2025-05-03

Members of our research group

Myriam Martin, Rebecca Trattner and Anna Blom  You can reach us by mailor by calling 040-33 78 30 and 040-33 15 20Vaishnavi Dandavate, postdoctoral fellowE-mail: vaishnavi [dot] dandavate [at] med [dot] lu [dot] sePia Ecke, undergraduate studentE-mail: Pia [dot] Ecke [at] med [dot] lu [dot] seAlexander Ekström, PhD studentE-mail: alexander [dot] ekstrom [at] med [dot] lu [dot] se (alexander[dot]ek

https://www.protein-chemistry.lu.se/members-our-research-group - 2025-05-03

Open positions

Here you can find description of open positions and internships in our research group. MSc StudentsWe often can offer thesis projects for Masters students within the projects conducted in our group. Please, contact Anna Blom (Anna [dot] Blom [at] med [dot] lu [dot] se (Anna[dot]Blom[at]med[dot]lu[dot]se)) directly for more details.PhD StudentsWe are always interested in reviewing PhD students appl

https://www.protein-chemistry.lu.se/open-positions - 2025-05-03

Research funding

Research funding supporting projects conducted in our research group: Swedish Research Council Cancerfonden Torsten Söderberg Foundation ALF Knut and Alice Wallenberg Foundation Novo nordisk fonden Erling-Persson Family Foundation Alfred Österlund Foundation  Grants for clinical research from Skåne University Hospital (including cancer) King Gustav Vth, 80-years Anniversary Foundation Diabetesfond

https://www.protein-chemistry.lu.se/research-funding - 2025-05-03

Anna Blom Research Group

The Medical Protein Chemistry research group headed by prof. Anna Blom is located at the Wallenberg Laboratory within Skåne University Hospital in Malmö. The group is focused on the complement system in health and disease. Our ambition is to make high quality basic science based on clinically relevant questions and yielding novel diagnostic approaches and clinical interventions. Our research is su

https://www.protein-chemistry.lu.se/anna-blom-research-group - 2025-05-03

start

Leading research in psychological defence About the institute... The Lund University Psychological Defence Research Institute (Forskningsinstitutet för psykologiskt försvar) is a multidisciplinary research unit within the Department of Communication. Our work focuses on the theory and practice of psychological defence, with a focus on research into analyzing and countering hostile information infl

https://www.psychologicaldefence.lu.se/start - 2025-05-03

About the institute

The Lund University Psychological Defence Research Institute (Forskningsinstitutet för psykologiskt försvar) is a multidisciplinary research unit within the Department of Communication. Our work focuses on the theory and practice of psychological defence and research into analyzing and countering hostile information influence operations and hybrid threats. The purpose of psychological defence is t

https://www.psychologicaldefence.lu.se/about-institute - 2025-05-03

ADAC.io

Attribution – Data – Analysis – Countermeasures. InterOperability ADAC.io is a Horizon project coordinated by the Psychological Defence Research Institute As of 1 February 2024, the Psychological Defence Research Institute coordinates the Horizon project ADAC.io, engaging seven partners in a three-year-long project. Based on the concept of Foreign Information Manipulation & Interference (FIMI) as

https://www.psychologicaldefence.lu.se/adacio - 2025-05-03

Research

Below are some of the main publications by the Psychological Defence Research Institute and our affiliates. 2025Hedling, E. (2025). Social identities and democratic vulnerabilities: Learning from examples of targeted disinformation. Hybrid CoE Paper, 24.  Hedling, E., & Ördén, H. (2025). Disinformation, deterrence and the politics of attribution, International Affairs, https://doi: 10.1093/ia/iiaf

https://www.psychologicaldefence.lu.se/research - 2025-05-03

Registration for Slutet

Register here for the reading group seminar on Mats Strandberg's Slutet. Name (required) Enter first and last name. E-mail address (required) Please enter your e-mail address. Dietary requirements Please let us know if you have any specific dietary requirements. The breakfast served will be vegetarian. Yes I want to borrow a book Leave this field blank

https://www.climatefutures.lu.se/form/registration-slutet - 2025-05-03

Registration for What it Means When a Man Falls From the Sky

Register here for the reading group seminar on Lesley Nneka Arimah's What it Means When a Man Falls From the Sky. Name (required) Enter first and last name. E-mail address (required) Please enter your e-mail address. Dietary requirements Please let us know if you have any specific dietary requirements. The breakfast served will be vegetarian. Yes I want to borrow a book Leave this field blank

https://www.climatefutures.lu.se/form/registration-what-it-means-when-man-falls-sky - 2025-05-03

Registration: Anthropo-scenes I: Introduction to Climate Fiction

Time: Feb 5, 18.00-20.00Venue: Room 230, Eden, Department of Political Science, Lund UniversityTo kick-start your writing process, we bring you an evening with three renowned experts in the field; Wytske Versteeg (Author of the Boy & other titles), Dr Graeme Macdonald (Professor at the Department of English at University of Warwick) and Paul G Raven (post-doc at Lund University and fiction writer)

https://www.climatefutures.lu.se/form/registration-anthropo-scenes-i-introduction-climate-fiction - 2025-05-03

Climate Change 101

a reading list We often get asked to recommend literature for a wide range of interests (first encounter with climate change, want to learn more, natural scientists who are keen on learning about environmental politics. So for 2019, we decided to put it all online. This is in no way a complete list, merely a starting point with our personal favorites. If you are looking for Climate Fiction we have

https://www.climatefutures.lu.se/climate-change-101 - 2025-05-03