Bacterial complement evasion strategies
As a first line of defense against pathogens and a mediator between innate and adaptive immunity, complement is a particular focus of evasion strategies developed by pathogens. We showed that one common strategy is to bind complement inhibitor C4BP, which leads to decreased opsonisation of bacteria with C3b impairing phagocytosis and allowing bacterial survival. It appears that binding of C4BP is
https://www.protein-chemistry.lu.se/projects/bacterial-complement-evasion-strategies - 2025-05-03