BACKGROUND: In the Netherlands, surgery for peritoneal metastases of colorectal cancer (PMCRC) is centralised, whereas PMCRC is diagnosed in all hospitals. This study assessed whether hospital of diagnosis affects treatment selection and overall survival (OS).METHODS: Between 2005 and 2015, all patients with synchronous PMCRC without systemic metastases were selected from the Netherlands Cancer Re

BACKGROUND: Experience with Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in a pioneer hospital resulted in a treatment protocol that has become the standard in the Netherlands. Outcome of CRS and HIPEC was reviewed to assure differences between the pioneer phase and the period wherein the Dutch HIPEC protocol was clinically implemented.METHODS: The first consec

Immune cells of the tumor microenvironment are central but erratic targets for immunotherapy. The aim of this study was to characterize novel patterns of immune cell infiltration in non-small cell lung cancer (NSCLC) in relation to its molecular and clinicopathologic characteristics. Lymphocytes (CD3+, CD4+, CD8+, CD20+, FOXP3+, CD45RO+), macrophages (CD163+), plasma cells (CD138+), NK cells (NKp4

PURPOSE: Intrauterine undernutrition is associated with increased risk of type 2 diabetes. Children born premature or small for gestational age were reported to have abnormal retinal vascularization. However, whether intrauterine famine act as a trigger for diabetes complications, including retinopathy, is unknown. The aim of the current study was to evaluate long-term effects of perinatal famine

Various biomarkers are available to support the diagnosis of neurodegenerative diseases in clinical and research settings. Among the molecular imaging biomarkers, amyloid-PET, which assesses brain amyloid deposition, and 18F-fluorodeoxyglucose (18F-FDG) PET, which assesses glucose metabolism, provide valuable and complementary information. However, uncertainty remains regarding the optimal timepoi

4th September 2013, Wednesday 17th QMOD-ICQSS Conference 3rd-5th September, 2014 Prague, Czech Republic Program Jointly organized by: Lund University, Linköping University & University of Economics, VŠE, Prague Welcome Address from the Founders of QMOD-ICQSS It is our great pleasure to welcome you to the 17th QMOD-ICQSS conference, the conference which has become one of the largest scientific conf

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/qmod_2014_final_program_with_welcome_20140819_1.pdf - 2025-08-29

Research Article Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus Natalia Avaliani,1 Ulrich Pfisterer,2 Andreas Heuer,2,3 Malin Parmar,2 Merab Kokaia,1 and My Andersson1 1Epilepsy Centre, Lund University Hospital, Lund, Sweden 2Developmental Neurobiology, Lund University, Lund, Sweden 3Molecular Neuromodulation, Lund University, Lund, S

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_stem_cells_international.pdf - 2025-08-29

COSM10: Introduction to Asian Studies (Autumn 2022) Course literature is 562 pages but an additional 100 pages may be added to keep up with current events and trends in the field. Amako, S. 2017. Methods for area studies and contemporary China study. 6(1): 2-28. [27 pages] Amrith, Sunil. 2011. Reconstructing the ‘Plural Society’: Asian Migration Between Empire and Nation, 1940-1948. Past and Prese

https://www.ht.lu.se/media/utbildning/dokument/kurser/COSM10/20222/COSM10.docx - 2025-08-29

Professor i fri konst Kontaktinformation E-post: joachim [dot] koester [at] khm [dot] lu [dot] seOrganisation Konsthögskolan i Malmö WebbplatsJoachim Koesters profil i Lunds universitets forskningsportalJoachim Koester är en dansk konstnär som har sin bas i Köpenhamn. Hans konstverk har visats på documenta X, Kassel; den 2:a Johannesburgbiennalen; Gwangjubiennalen 1995; den 54:e Venedigbiennalen;

https://www.khm.lu.se/joachim-koester - 2025-08-28

Recent genome-wide association studies (GWASs) have identified a locus on chromosome 1p13 strongly associated with both plasma low-density lipoprotein cholesterol (LDL-C) and myocardial infarction (MI) in humans. Here we show through a series of studies in human cohorts and human-derived hepatocytes that a common noncoding polymorphism at the 1p13 locus, rs12740374, creates a C/EBP (CCAAT/enhancer

The mechanisms involved in the maintenance of memory IgE responses are poorly understood, and the role played by germinal center (GC) IgE(+) cells in memory responses is particularly unclear. IgE(+) B cell differentiation is characterized by a transient GC phase, a bias toward the plasma cell (PC) fate, and dependence on sequential switching for the production of high-affinity IgE. We show here th

Retrotransposons are mobile DNA sequences duplicated via transcription and reverse transcription of an RNA intermediate. Cis-regulatory elements encoded by retrotransposons can also promote the transcription of adjacent genes. Somatic LINE-1 (L1) retrotransposon insertions have been detected in mammalian neurons. It is, however, unclear whether L1 sequences are mobile in only some neuronal lineage

Sepsis is the major cause of mortality across intensive care units globally, yet details of accompanying pathological molecular events remain unclear. This knowledge gap has resulted in ineffective biomarker development and suboptimal treatment regimens to prevent and manage organ dysfunction/damage. Here, we used pharmacoproteomics to score time-dependent treatment impact in a murine Escherichia

Background Epithelial damage, repair and remodelling are critical features of chronic airway diseases including chronic obstructive pulmonary disease (COPD). Interleukin (IL)-33 released from damaged airway epithelia causes inflammation via its receptor, serum stimulation-2 (ST2). Oxidation of IL-33 to a non-ST2-binding form (IL-33ox) is thought to limit its activity. We investigated whether IL-33

ETS gene fusions have been characterized in a majority of prostate cancers; however, the key molecular alterations in ETS-negative cancers are unclear. Here we used an outlier meta-analysis (meta-COPA) to identify SPINK1 outlier expression exclusively in a subset of ETS rearrangement-negative cancers (similar to 10% of total cases). We validated the mutual exclusivity of SPINK1 expression and ETS

An abnormal nevus phenotype is associated with an increased risk of melanoma. We report a pooled analysis conducted using individual nevus data from 15 case-control studies (5,421 melanoma cases and 6,966 controls). The aims were to quantify the risk better and to determine whether relative risk is varied by latitude. Bayesian unconditional logistic random coefficients models were employed to stud

BACKGROUND: Guidelines recommend measuring blood pressure (BP) in both arms, adopting the higher arm readings for diagnosis and management. Data to support this recommendation are lacking. We evaluated associations of higher and lower arm systolic BPs with diagnostic and treatment thresholds, and prognosis in hypertension, using data from the Inter-arm Blood Pressure Difference - Individual Partic

ANNUAL REPORT 2018 CONTENTS FOREWORD 2018 IN BRIEF PEOPLE SELECTED HIGHLIGHTS PER AREA NEWS 2018 VISIBILITY WORLDWIDE SHARING KNOWLEDGE INFRASTRUCTURE EDUCATION & OUTREACH SCIENTIFIC PUBLICATIONS 2018 NANOLUND AWARDS GRADUATE EDUCATION FUNDING ORGANISATION . . . . . . . . . . . . . . . . . . . . . . . . . 2 . . . . . . . . . . . . . . . . . . . . . . . 4 . . . . . . . . . . . . . . . . . . . . . .

https://www.nano.lu.se/sites/nano.lu.se/files/2018_arsrapport_nanolund1.pdf - 2025-08-29

Post-Growth on the Move The Environmental Movement as Agent of Change for the Transition to a Post-Growth Economy - Evidence from Germany Anja Humburg anja.humburg@gmx.net Supervisor: Turaj Faran May 16, 2011 A thesis submitted in partial fullment of the requirements of Lund University International Master's Programme for Environmental Studies and Sustainability Science (LUMES). 1 Abstract This th

https://www.lumes.lu.se/sites/lumes.lu.se/files/humburg_anja_thesis_2011.pdf - 2025-08-29