Haemophilia A and haemophilia B are congenital X-linked bleeding disorders caused by deficiency of coagulation factor VIII (FVIII) and IX (FIX), respectively. The preferred treatment option for patients with haemophilia is replacement therapy. For patients with severe disease, prophylactic replacement of coagulation factor is the treatment of choice; this has been shown to reduce arthropathy signi

Introduction: The directionality of semantic change is problematic in traditional comparative models of language reconstruction. Compared to, e.g., phonological and morphological change, the directions of meaning change over time are potentially endless and difficult to reconstruct. The current paper attempts to reconstruct the mechanisms of lexical meaning change by a quantitative model. We use a

Induced pluripotent stem cell (iPSC) reprogramming is inefficient and understanding the molecular mechanisms underlying this inefficiency holds the key to successfully control cellular identity. Here, we report 24 reprogramming roadblock genes identified by CRISPR/Cas9-mediated genome-wide knockout (KO) screening. Of these, depletion of the predicted KRAB zinc finger protein (KRAB-ZFP) Zfp266 stro

OBJECTIVE: Although injury burden prompts elite athletics (track and field) athletes to engage in injury management, little is known about their health literacy. We investigated musculoskeletal (MS) health literacy in world-leading athletics athletes and associations with prechampionship injury acknowledgement by reduction of training load in different socioeconomic environments.METHODS: Adult and

In order to achieve environmental goals, the impact of the European building stock on the environment needs to be reduced through renovation measures. However, regarding heritage buildings, the choice of measure(s) must simultaneously consider the preservation of cultural and historical values. Besides the impact on such values, energy-efficiency measures can result in increased risks for moisture

Motivation for study: Flooding In, Flooding Out:  How does post disaster volunteering build community resilience?   Harriet Barker  16 May 2011    Supervised by Lena Christensen   A thesis submitted in partial fulfillment of the requirements of Lund University International Master’s  Programme in Environmental Studies and Sustainability Science (LUMES) for the degree of Master of Science   i Abstr

https://www.lumes.lu.se/sites/lumes.lu.se/files/barker_harriet_thesis_2011.pdf - 2025-06-07

Forskare Kontaktinformation E-post: mats [dot] lindeskog [at] nateko [dot] lu [dot] seOrganisation Institutionen för naturgeografi och ekosystemvetenskap Hämtställe: 16 WebbplatsMats Lindeskogs profil i Lunds universitets forskningsportalAndra roller Forskare BECC: Biodiversity and Ecosystem services in a Changing Climate Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filt

https://www.nateko.lu.se/sv/mats-lindeskog - 2025-06-06

Docent | Universitetslektor Kontaktinformation E-post: pinar [dot] dinc [at] svet [dot] lu [dot] seOrganisation Centrum för Mellanösternstudier (CMES) Hämtställe: 18 WebbplatsPinar Dincs profil i Lunds universitets forskningsportalAndra roller Forskare MECW: The Middle East in the Contemporary World Docent Statsvetenskapliga institutionen Forskare Statsvetenskapliga institutionenDr. Pınar Dinç har

https://www.svet.lu.se/pinar-dinc - 2025-06-06

SKOB14-18H, Introduktion till strategisk kommunikation i teori och prakt 2018-08-20 - 2019-02-28 SKOB14-18H, Introduktion till strategisk kommunikation i teori och prakt Tid Undervisningstyp Studentgrupp Undergrupp Lokaldel, Platskommentar Externa lärare, Personal Kurs Titel, Publik kommentar v 36 Må 2018-09-03 10:00 - 13:00 Introduktion, Upprop SKOB14 3T U203 Cecilia Cassinger, James Pamment, Len

https://www.isk.lu.se/sites/isk.lu.se/files/schema_skob14_h18.pdf - 2025-06-07

REST suppression mediates neural conversion of adult human fibroblasts via microRNA‐dependent and ‐independent pathways Research Article REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways Janelle Drouin-Ouellet1,†, Shong Lau1,†, Per Ludvik Brattås1, Daniella Rylander Ottosson1, Karolina Pircs1, Daniela A Grassi1, Lucy M Collins2,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_embo_mol_med.pdf - 2025-06-07

A Just Transition, Grounded in Human Rights: The Role of Businesses - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Vacancies Annual Review Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis

https://rwi.lu.se/news/a-just-transition-grounded-in-human-rights-the-role-of-businesses/ - 2025-05-04

Gener fungerar som instruktioner för vad cellen skall producera. Det är aktiveringen och hämningen av gener som ger upphov till många olika typer av celler i människans kropp som till exempel hudceller, blodceller och nervceller. Dessa celler samarbetar med varandra för att tillsammans skapa den flercelliga organismen: människan. Det finns två huvudkategorier av celler i kroppen, somatiska celler Scientists are now able to directly convert one somatic cell type into another using a procedure known as direct lineage reprogramming or transdifferentiation. In this procedure, transcription factors which are important for initiating a rewriting of the gene expressions are introduced in the cell. One specific type of reprogramming involves generating dopamine producing neurons from human adult f

Motivation: CoGenT++ is a data environment for computational research in comparative and functional genomics, designed to address issues of consistency, reproducibility, scalability and accessibility. Description: CoGenT++ facilitates the re-distribution of all fully sequenced and published genomes, storing information about species, gene names and protein sequences. We describe our scalable imp

Through funding from the National Park Service's American Battlefield Protection Program, geographic information technologies were employed to create a high resolution, spatially accurate representation of the 1775 landscape of Boston's Inner Harbor and to conduct a geospatial and temporal assessment of the location, extent, and preservation potential of an American Revolutionary War battlefield a

Although effective therapies for haemophilia have been available for decades, the prevention and treatment of joint disease remain major clinical concerns for all haemophilia patients. Early identification of joint disease is vital to initiate or modify treatment, and prevent arthropathy. However, there remains a need for more sensitive and accurate methods, which may also detect improvement in pa

In this correspondence, unequal error-correcting capabilities of convolutional codes are studied. For errors in the information symbols and code symbols, the free input- and output-distances, respectively, serve as '' unequal '' counterparts to the free distance. When communication takes place close to or above the channel capacity the error bursts tend to be long and the free distance is not any

Angiogenesis is a key event in cancer progression and therefore a promising target in cancer treatment. Galectin-1, a β-galactoside binding lectin, is up-regulated in the endothelium of tumors of different origin and has been shown to be the target for anginex, a powerful anti-angiogenic peptide with anti-tumor activity. Here we show that when bound to anginex, galectin-1 binds various glycoprotei

The case is presented of a child who developed rhinoconjunctivitis, angioedema and asthma by sensitization to Sapelli wood, which was used in his father's carpentry. Positive skin-prick test, high levels of specific immunoglobulin E by ELISA and a positive conjunctival challenge test suggest a type I hypersensitivity mechanism to this wood. This is the first case report of sensitization to Sapelli

We examined whether mesial temporal (Me) tau relates to cognitive performance in 47 amyloid-β (Aβ)-negative, cognitively normal older adults (>60 years old). Me-tau was measured using [18F]flortaucipir–positron emission tomography standardized uptake value ratio. The effect of continuous and categorical (stratified at standardized uptake value ratio = 1.2 [21% Me-positive]) Me-tau on cognition (mi