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Background: Lower limb deep vein thrombosis (DVT) is common in emergency departments (EDs) and can be fatal if left untreated due to the risk of progression to pulmonary embolism (PE). In Scandinavia, DVT diagnosis typically relies on ultrasound performed outside the ED in the diagnostic departments. However, international guidelines now recommend combining limited/proximal compression ultrasound
BACKGROUND: Oesophagectomy, a corner stone in curative treatment of oesophageal cancer, is a complex procedure with high complication rates. Postoperative gastric tube decompression is debated and some centres are abandoning routine nasogastric (NG) tube use. We hypothesised that postoperative NG tube removal is non-inferior to five days of NG tube decompression, with regard to the risk of anastom
Surveys in the Milky Way and Large Magellanic Cloud have revealed that the majority of massive stars will interact with companions during their lives. However, knowledge of the binary properties of massive stars at low metallicity, and therefore in conditions approaching those of the Early Universe, remain sparse. We present the Binarity at LOw Metallicity (BLOeM) campaign, an ESO large programme
Context. Hot Jupiters (HJs) with close-by planetary companions are rare, with only a handful of them having been discovered so far. This could be due to their suggested dynamical histories, which lead to the possible ejection of other planets. TOI-2109 b is special in this regard because it is the HJ with the closest relative separation from its host star, being separated by less than 2.3 stellar
Context. Since the discovery of the first exoplanet almost three decades ago, the number of known exoplanets has increased dramatically. By beginning of the 2000s it was clear that dedicated facilities to advance our studies in this field were needed. The CHaracterising ExOPlanet Satellite (CHEOPS) is a space telescope specifically designed to monitor transiting exoplanets orbiting bright stars. I
Introduction. Electrodialytic processes have become relevant technology in promoting sustainability within the food industry. Bipolar membrane electrodialysis (EDBM) offers an efficient and eco-friendly alternative for skim milk (SM) acidification, eliminating the need for added acids that affect milk properties and mineral composition [1-2]. In this study, the fouling behavior of bipolar membrane
The potential of Small Modular Reactors (SMRs) is currently explored in the world. SMRs as technology is still under development but is introduced to the public. In this stage, when much is still uncertain and unknown, media is important. The benefits and risks related to this new technology articulated in media potentially shape different actors' expectations and attitudes towards the technology.
BackgroundLong-term oxygen therapy (LTOT) given for at least 15 hours/day improves survival in patients with severe chronic hypoxemia. However, the recent REDOX trial showed that LTOT prescribed for 24 hours/day was not superior to 15 hours/day in terms of death, hospitalizations, or self-reported outcomes. We aimed to examine the cost effectiveness of prescribing LTOT for 24 versus 15 hours/day.M
Aims Academic journals are essential for advancing knowledge, yet gender disparities in orthopaedic authorship persist. While most previous studies focus authorship trends on mainly North American journals, this study analyzes gender distribution among primary and senior authors, along with the geographical origins of articles, in three orthopaedic journals based in Europe and North America. Metho
Background The dura mater has a permeable vasculature similar to that of peripheral organs, and is separated from the brain, which is enclosed within the arachnoid barrier. Fluid and solute transport across the arachnoid barrier between the subarachnoid space (SAS) and dura is crucial for brain waste clearance and immune surveillance, but few neuroimaging approaches can capture this dynamic proces
BACKGROUND: Public health policies and healthcare quality play a pivotal role on the health outcome level and disparities across sociodemographic groups. However, there is little evidence on their role on disparities in life expectancy (LE) and life disparity (LD) in low and middle income countries. The present study aimed to assess the contributions of avoidable mortality, as a measure of inter-s
BACKGROUND: Many factors influence housing choices among older adults, but far from all have been identified. There is little systematic analysis that has included economic factors and virtually no knowledge about the interplay among perceived costs of moving, health status, and the mobility rate of older homeowners. It is currently unclear whether economic factors influence older adults' willingn
Background: Biologic effectiveness is often assessed as response, a term that eludes consistent definition. Identifying those most likely to respond in real-life has proven challenging. Objective: To explore definitions of biologic responders in adults with severe asthma and investigate patient characteristics associated with biologic response. Methods: This was a longitudinal cohort study using d
IMPORTANCE Twin studies have found that posttraumatic stress disorder (PTSD) is influenced by both genetic and environmental factors within a generation. No study has used an adoption design, which can address questions about the degree and sources of cross-generational transmission of adverse stress responses (ASRs) and PTSD. OBJECTIVES To examine whether ASRs or PTSD are transmitted from parents
Importance: Electroconvulsive therapy (ECT), wherein a generalized epileptic seizure is induced, is a treatment for major depressive disorder (MDD). Currently, it is unclear whether there is an association between seizure length and treatment outcome. Objective: To explore the association between seizure duration, potential confounding variables, and ECT treatment outcome. Design, Setting, and Par
By combining acoustic fields and liquid flows in microchannels we develop tools to chart and separatebiological particles based on their bio-mechanical properties. I will present an overview of three ongoingprojects where acoustic forces are utilized to separate blood cells.We studied the packing behavior of whole blood in a sound field. We discovered that cells self-organizesuch that red blood cells
BackgroundPsoriatic arthritis (PsA) is a chronic arthritis affecting people with psoriasis. If untreated, it may lead to disability. Recommended drugs are non‐steroidal anti‐inflammatory drugs (NSAIDs), corticosteroids, conventional synthetic disease‐modifying anti‐rheumatic drugs (csDMARDs), biologic DMARDs (bDMARDs), and targeted synthetic DMARDs (tsDMARDs). Tumour necrosis factor inhibitors (TN
