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Atheroprotective Effects of Alum Are Associated With Capture of Oxidized LDL Antigens and Activation of Regulatory T Cells.

The immune system represents a promising novel target for prevention of atherosclerosis. Several pilot vaccines that reduce atherosclerosis in experimental animals have been developed. The aluminum hydroxide adjuvant Alum has been shown to have antiatherogenic properties in itself, suggesting that it may be a suitable adjuvant in possible future atherosclerosis vaccines. To characterize the immune

What do users tell you?: Considerations when collecting and analyzing opinions in traffic planning

Users’ perceptions of their traffic environment are of interest to both researchers and practitioners within the realm of traffic planning. The aim of this thesis is to contribute to methodological considerations when collecting and analyzing users’ opinions on features in their traffic environment. Questionnaires were sent out to residents along four arterial streets in Malmö, Sweden, covering qu

Lessons learnt at ICA2001. IWA Conference on Instrumentation, Control and Automation.

This paper gives an introduction as well as some general experiences and conclusions from the 1st IWA Conference on Instrumentation, Control and Automation (ICA2001), June 3-7, 2001, Malmö, Sweden. The highlights from the different sessions of the conference are summarised and some challenges for the coming years, with regard to ICA within the field of wastewater treatment, are also discussed.

Selective inhibition by simvastatin of IRF3 phosphorylation and TSLP production in dsRNA-challenged bronchial epithelial cells from COPD donors.

Background and purpose: Statin treatment may ameliorate viral infection-induced exacerbations of chronic obstructive pulmonary disease (COPD), which exhibit Th2-type bronchial inflammation. Thymic stromal lymphopoietin (TSLP), a hub cytokine switching on Th2-inflammation, is overproduced in viral and dsRNA-stimulated bronchial epithelial cells from COPD donors. Hence, TSLP may be causally involve

Purification of alpha1-antichymotrypsin from human plasma with recombinant M. catarrhalis ubiquitous surface protein A1.

Alpha 1-antichymotrypsin (ACT) inhibits chymotrypsin-like enzymes, particularly neutrophil cathepsin G. Moreover, ACT in its native form suppresses chemotaxis of neutrophils and decreases neutrophil production of superoxide radicals. We recently showed that Moraxella catarrhalis ubiquitous surface protein (Usp) A1 is able to specifically bind ACT in the context of a novel virulence mechanism. In t

Knowledge bases and Regional Innovation Systems: Comparing Nordic Clusters.

The analysis of the importance of different types of regional innovation systems must take place within a context of the actual knowledge base of various industries in the economy, as the innovation processes of firms are strongly shaped by their specific knowledge base. In this paper, we shall distinguish between two types of knowledge base: analytical and synthetic. These types indicate differen