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Probabilistic approach to geomagnetic field modelling of data with age uncertainties and post-depositional magnetisations

Holocene geomagnetic field models are used to study processes in Earth's core, millennial scale variations in solar activity and to relatively date geological and archaeological archives. Constructing models from magnetic field directions and intensities stored in archaeological artefacts, igneous rocks and sediment records is challenging due to the sparse data distribution and the large chronolog

The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cells

Changes in the location of γ-tubulin ensure cell survival and preserve genome integrity. We investigated whether the nuclear accumulation of γ-tubulin facilitates the transport of proliferating cell nuclear antigen (PCNA) between the cytosolic and the nuclear compartment in mammalian cells. We found that the γ-tubulin meshwork assists in the recruitment of PCNA to chromatin. Also, decreased levels

Hållbart arbetsliv för alla åldrar : swAge modellen

Bakgrund Den 20 januari 2020 senarelades ålderspensionen i Sverige för alla yrkesgrupper. Samtidigt ökar den arbetsrelaterade sjukligheten. I ett framtidsperspektiv kommer efterfrågan på arbetskraft som kan och vill arbeta till en högre ålder att öka utifrån den globala demografiska förändringen. Att medverka till en god anställningsbarhet (employability) och hälsa är därför en central fråga och uHållbart arbetsliv för alla åldrar – swAge modellenKerstin Nilsson1, 21Högskolan Kristianstad, 2Lunds universitetBakgrundDen 20 januari 2020 senarelades ålderspensionen i Sverige för alla yrkesgrupper. Samtidigtökar den arbetsrelaterade sjukligheten. I ett framtidsperspektiv kommer efterfrågan påarbetskraft som kan och vill arbeta till en högre ålder att öka utifrån den globala demografiskaförändr

Plastic dinosaurs : Digging deep into the accelerating carbon lock-in of plastics

The continued expansion of plastics production all over the world entrenches modern societies and life styles deeper in the dependence on fossil resources. This research note develops the main aspects of the carbon lock-in in the plastics industry and how it extends into many aspects of contemporary life. With data collected from trade press and reports, we present insights of the investment trend

In Absence of a Working Place : A Gig Worker’s Sense Making of Work Community

In recent years, gig work – short-term and temporary assignments mediated via digital platforms – has captured the interest of media and research and is growing as an area of academic inquiry. Previously research has mainly focused on the regulations and breadth of gig work. Gig work can be been understood as a significant break from ‘standard employment relationship’, meaning that we are now headIn recent years, gig work – short-term and temporary assignments mediated via digital platforms – has captured the interest of media and research and is growing as an area of academic inquiry. Previously research has mainly focused on the regulations and breadth of gig work. Gig work can be been understood as a significant break from ‘standard employment relationship’, meaning that we are now head

Attraktivt och hållbart arbetsliv på människors villkor : Arbete, hälsa och ledarskap med SwAge-modellen i teori och praktik

Hur kan vi skapa ett hållbart arbetsliv där individer mår bra, kan, vill och orkar befinna sig? Hur kan arbetsgivare, organisationer, företag ta till vara på det humankapital som individer utgör? Hur kan hälsa, inklusion, motivation, kunskap och kompetens värnas och utvecklas genom hela arbetslivet? I ett framtidsperspektiv kommer efterfrågan på arbetskraft som kan och vill arbeta till en högre ålHur kan vi skapa ett hållbart arbetsliv där individer mår bra, kan, vill och orkar befinna sig? Hur kan arbetsgivare, organisationer, företag ta till vara på det humankapital som individer utgör? Hur kan hälsa, inklusion, motivation, kunskap och kompetens värnas och utvecklas genom hela arbetslivet? I ett framtidsperspektiv kommer efterfrågan på arbetskraft som kan och vill arbeta till en högre ål

Predictors of unacceptable pain with and without low inflammation over 5 years in early rheumatoid arthritis-an inception cohort study

OBJECTIVES: Pain is a major symptom in patients with rheumatoid arthritis (RA). In early RA, pain is usually due to synovitis, but can also persist despite effective anti-inflammatory treatment. The objective of this study was to investigate the pain course over time and predictors of unacceptable pain and unacceptable pain with low inflammation, in patients with early RA.METHODS: An inception coh

Modifiable and non-modifiable risk factors for atherothrombotic ischemic stroke among subjects in the malmö diet and cancer study

Risk factors for ischemic stroke is suggested to differ by etiologic subtypes. The purpose of this study was to examine the associations between modifiable and non-modifiable risk factors and atherothrombotic stroke (i.e., excluding cardioembolic stroke), and to examine if the potential benefit of modifiable lifestyle factors differs among subjects with and without predisposing comorbidities. Afte

IFN-β rescues neurodegeneration by regulating mitochondrial fission via STAT5, PGAM5, and Drp1

Mitochondrial homeostasis is essential for providing cellular energy, particularly in resource-demanding neurons, defects in which cause neurodegeneration, but the function of interferons (IFNs) in regulating neuronal mitochondrial homeostasis is unknown. We found that neuronal IFN-β is indispensable for mitochondrial homeostasis and metabolism, sustaining ATP levels and preventing excessive ROS b

Augmenting a dynamic hip screw with a calcium sulfate/hydroxyapatite biomaterial

Internal fixation failure in hip fractures can lead to reoperation. Calcium sulfate/hydroxyapatite (CaS/HA) is a biomaterial that can be used for augmenting fracture fixation. We aimed to determine whether an injection of 2 ml CaS/HA increases the fixation of a dynamic hip screw inserted in synthetic and human trabecular bone. The study consists of two parts: 1) synthetic bone blocks (n = 74), wit