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Wavelength-dependent photoproduct formation of phycocyanobilin in solution - Indications for competing reaction pathways
Phycocyanobilin (PCB), an open-chain tetrapyrrole, makes up - slightly modified - the chromophore in phytochromes, the importance of which triggered model studies on the photochemistry of PCB in solution. We use pump-wavelength dependent femtosecond transient absorption spectroscopy including the near-IR region for probing to gain new insight into the photoreaction. The data reveal the coexistence
CD4 Cell Levels during Treatment for Tuberculosis (TB) in Ethiopian Adults and Clinical Markers Associated with CD4 Lymphocytopenia.
The clinical correlations and significance of subnormal CD4 levels in HIV-negative patients with TB are unclear. We have determined CD4 cell levels longitudinally during anti-tuberculosis treatment (ATT) in patients, with and without HIV co-infection, and their associations with clinical variables.
Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA
Polymorphisms within HLA gene loci are strongly associated with susceptibility to autoimmune disorders; however, it is not clear how genetic variations in these loci confer a disease risk. Here, we devised a cell-surface MHC expression assay to detect allelic differences in the intrinsic stability of HLA-DQ proteins. We found extreme variation in cell-surface MHC density among HLA-DQ alleles, indi
Harmful somatic amino acid substitutions affect key pathways in cancers.
Cancer is characterized by the accumulation of large numbers of genetic variations and alterations of multiple biological phenomena. Cancer genomics has largely focused on the identification of such genetic alterations and the genes containing them, known as 'cancer genes'. However, the non-functional somatic variations out-number functional variations and remain as a major challenge. Recurrent so
Rural Women in Bangladesh : The Legal Status of Women and the Relationship between NGOs and Religious Groups
Popular Abstract in Swedish Bangladesh är ett av världens folkrikaste muslimska länder. Sedan självständigheten har invånarna – trots politisk oro, massiva naturkatastrofer och utbredd administrativ korruption – upplevt en positiv utveckling, särskilt vad gäller kvinnors utbildning, hälsovård och familjeplanering. Denna avhandling diskuterar kvinnors levnadsförhållanden på landsbygden med fokus påBangladesh is one of the largest Muslim countries in the world. In spite of political turmoil, frequent natural disasters and widespread corruption it has, in less than four decades after its birth as an independent state, gained visible success in human development - especially the education of women and girls, family planning and health, and microcredit to the poor. As a Muslim country it has s
Iterated Second-Order Label Sensitive Pooling for 3D Human Pose Estimation
Recently, the emergence of Kinect systems has demonstrated the benefits of predicting an intermediate body part labeling for 3D human pose estimation, in conjunction with RGB-D imagery. The availability of depth information plays a critical role, so an important question is whether a similar representation can be developed with sufficient robustness in order to estimate 3D pose from RGB images. Th
A New View on an Old Debate: Type of Cue-Conflict Manipulation and Availability of Stars Can Explain the Discrepancies between Cue-Calibration Experiments with Migratory Songbirds.
Migratory birds use multiple compass systems for orientation, including a magnetic, star and sun/polarized light compass. To keep these compasses in register, birds have to regularly update them with respect to a common reference. However, cue-conflict studies have revealed contradictory results on the compass hierarchy, favoring either celestial or magnetic compass cues as the primary calibration
Potential Biomarkers for Radiation-Induced Renal Toxicity following 177Lu-Octreotate Administration in Mice.
C57BL/6N mice were i.v. injected with 0, 30, 60, 90, 120, or 150 MBq 177Lu-octreotate (0, 16, 29, 40, 48, and 54 Gy to the kidneys). At 4, 8, and 12 months after administration, radiation-induced effects were evaluated in relation to (a) global transcriptional variations in kidney tissues, (b) morphological changes in the kidneys, (c) changes in white and red blood cell count as well as blood leve
Review of the book Publik arkeologi
Review of the book Publik arkeologi (In English: Public Archaeology), edited by Fredrik Svanberg and Katty H. Wahlgren
Rektalpalpation ska självklart göras i vissa fall
Replik till Docent Peter Gunvén gällande rektalpalpation.A reply to associate professor Peter Gunvén regarding digital rectal examination.
Pressurized Hot Water Extraction of anthocyanins from red onion: A study on extraction and degradation rates
Pressurized Hot Water Extraction (PHWE) is a quick, efficient and environmentally friendly technique for extractions. However. when using PHWE to extract thermally unstable analytes, extraction and degradation effects occur at the same time, and thereby compete. At first, the extraction effect dominates, but degradation effects soon take over. In this paper, extraction and degradation rates of ant
The role of seniority-zero states in nuclear level densities
At low excitation energies seniority-zero states dominate the level density of K = 0 bands in deformed even even nuclei, while they play no role at higher excitation energies. We describe the level densities in a Fermi-gas model as well as in a combinatorial level-density model and compare to detailed experimental data for some rare-earth nuclei. An explanation is provided for recent observations
Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array-comparative genomic hybridization
We aimed to characterize the genomic profiles of adenocarcinomas in the gastroesophageal junction in relation to cancers in the esophagus and the stomach. Profiles of gains/losses as well as gene expression profiles were obtained from 27 gastroesophageal adenocarcinomas by means of 32k high-resolution array-based comparative genomic hybridization and 27k oligo gene expression arrays, and putative
Molluscs as evidence for a late Pleistocene and early Holocene humid period in the southern coastal desert of Peru (14.5 degrees S)
The southern Peruvian coastal desert around Palpa, southern Peru (14.5 degrees S) is currently characterized by hyper-arid conditions. However, the presence of two species of molluscs (Scutalus, Pupoides) and desert-loess deposits indicates the past development of semi-desert and grassland ecosystems caused by a displacement of the eastern desert margin due to hydrological changes. Radiocarbon dat
Optimal management of invasive species with different reproduction and survival strategies
In this paper, a numerical model is developed for analyzing the role of species life history and age structure for the optimal management of a commercial resident species that is exposed to an invasive species. It is shown that reproduction and mortality characteristics of both species ands age structure of the invader at the time of invasion are important for the costs of invasions when the invad
On resilience of distributed routing in networks under cascade dynamics
Comparison of different microscopic methods for the study of starch and other components within potato cells
Surface structure and reactivity of Pd(100) during CO oxidation near ambient pressures
The surface structure of Pd(100) during CO oxidation was measured using a combination of a flow reactor and in situ surface X-ray diffraction coupled to a large-area 2-dimensional detector. The surface structure was measured for P-O2/P-CO ratios between 0.6 and 10 at a fixed total gas pressure of 200 mbar and a fixed CO pressure of 10 +/- 1 mbar. In conjunction with the surface structure the react
Rasch Analysis of the Profiles of Occupational Engagement in people with Severe mental illness (POES) instrument.
The Profiles of Occupational Engagement in people with Severe mental illness (POES) instrument was developed to study time use profiles of occupations and measure the extent they are characterized by engagement. However, the dimensional factors are not known. The aim of the present study was to establish the internal construct validity of the POES using the Rasch measurement model.