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The control of synthetic genetic regulatory networks is an emerging engineering challenge. In this study, we propose a new synthetic genetic network that behaves as a digital clock, producing square waveform oscillations. We analyze two models of the network: a deterministic model based on Michaelis-Menten kinetics, as well as a stochastic model based on the Gillespie algorithm. Both models predic
In an investigation by the Swedish Cancer Society, the present status, critical issues and future aspects and potentials were described by an expert group for each of nine major areas of radiation therapy research, This report deals with medical imaging for improved medical diagnosis including tumour detection, staging and characterization, treatment planning, guiding and verification, evaluation
The effects of varying pan temperature and meat patty diameter on heat (temperature at the centre (5 mm) and 2 mm below the surface) and mass transfer (total, water and fat loss) of beefburgers prepared by double-sided frying were studied, The porosity of the fried beefburgers was determined based on the volume shrinkage and density measurements. The thawing time measured at the centre of the beef
Steady-state absorption and femtosecond time-resolved spectroscopic studies have been carried out on astaxanthin dissolved in CS2, methanol, and acetonitrile, and in purified alpha-crustacyanin. The spectra of the S-0 -> S-2 and S-1 -> S-n transitions were found to be similarly dependent on solvent environment. The dynamics of the excited-state decay processes were analyzed with both single wavele
We report on the preliminary results from a study of the decay of the I-pi = 8(+) T-1/2 = 2 mu s isomer in Pd-96 performed as part of the Stopped-Beam RISING campaign within the Rare Isotope Investigation at GSI (RISING). The Pd-96 ions were produced following the projectile fragmentation of a 750 MeV per nucleon Ag-107 primary beam. The reaction products were separated and identified by the in-fl
Osteoarthritis is a heterogeneous and multifactorial disease with many pathogenic mechanisms implicated in its development and progression. Although osteoarthritis is a manifestation of certain metabolic, mechanical or inflammatory events, several distinct forms of osteoarthritis are inherited as dominantly acquired Mendelian traits. Gathering evidence is showing that inheritance and possible muta
The cautious regulator based on one-step minimization of a quadratic loss function is easy to derive and seems to work well in many cases. A serious draw-back, however, is the possibility for turn-off. The present report is a small simulation study of a simple turn-off reducing scheme.This work was supported by the Swedish Board for Technical Developmentunder contract No. 7643804.
The purpose of the present study was to investigate the distribution of suicide during the months of the year and the days of the week in severe depression. A total of 1206 in-patients rated at discharge from the Department of Psychiatry, Lund, Sweden, on a multiaxial diagnostic schedule received the diagnosis severe depression/melancholia between 1956 to 1969. When followed up to 1998, a total of
The aim was to establish an accurate, reproducible, and simple method to evaluate functional recovery after different types of nerve injuries to the brachial plexus of rats. To that end, pawprints, measured as distance between the first and fourth and second and third digits, were used for evaluation of injuries including crush injury, transection/repair, or graft repair of the median, ulnar, and
Popular Abstract in Swedish Huvudsyftet med den utförda forskningen var att öka förståelsen för hur variabiliteten hos styrkevärden i trä påverkar tillförlitligheten hos en träkonstruktion. Jämfört med andra byggnadsmaterial som tex stål och betong har trä markant högre variabilitet i styrke- och styvhetsegenskaper både mellan och inom element. I byggnadsnormer tar man generellt inte hänsyn till The main purpose of the performed research presented in this thesis is to increase the understanding of the effect of variability of strength properties on the reliability of timber structural systems. Compared to other structural materials such as steel and concrete, structural timber has a considerably higher variability of strength both within and between members. The advantage of the low proba
The title compound, [Pt2Cl2(C6H5)2(C2H6OS)2] or [Pt([bold mu]-Cl)Ph(dmso)]2 (dmso is dimethyl sulfoxide), is a dimer with a pseudo square-planar coordination geometry around the Pt atoms, with two bridging Cl ligands creating a four-membered ring at the centre of the dimer. The complex is centrosymmetric, thus necessitating a trans configuration, with one dmso and one phenyl ligand coordinated to
Natural lifetimes of some highly excited levels in the Pb-I spectrum have been measured by the zero field level crossing (Hanle) method. The levels were reached by optical excitation from the metastable 6p2 3P2 and 6p2 3P1 states, were a considerable population had been created by means of adc discharge in a Pb atomic beam. An atomic beam source producing atoms in metastable states is described. F
Our previous studies indicated that acute haemorrhage leads to a pronounced increase in the release of endothelium-derived nitric oxide (EDNO) graded in relation to the magnitude of the blood loss. The EDNO-induced vasodilatation, confined selectively to the arterial 'feeder' vessels, attenuates the concomitant reflex adrenergic constriction and thereby prevents deleterious reduction of blood flow
Optical data storage devices and erasable memories with storage densities in the range of terabits/cm2, all-optical devices for communication like optical bit-rate converters, routers and image processors can become a reality with photon-echo-based frequency-selective materials. In photon-echo-based optical data storage and data processing the photon-echo-output intensity generally is about 0.1–1%
Modified ultrafiltration (MUF) is often used in conjunction with paediatric cardiac surgery with cardiopulmonary bypass (CPB) and is thought to improve clinical outcome. It is unclear whether these improvements (if any) are due to the removal of inflammatory mediators. In this prospective study, 18 children aged 12-24 months undergoing uncomplicated cardiac surgery with methylprednisolone added in
