The tumor microenvironment can act so as to stimulate or reject tumor cells. Among the determining factors are cytokines produced, for example, by infiltrating immune cells, tumor cells, and fibroblasts. External radiotherapy has been shown to be able to activate an immune response against tumor cells with cytokine signaling as an important part of the activation. The aim of this study was to eval

This paper presents four different tangible interactive prototypes designed to support the continuation of balance rehabilitation at home. The interactive prototypes are designed to provide a more enjoyable and experience when performing balance rehabilitation exercises. Early results from preliminary tests with stroke survivors and rehabilitation professionals are promising. The aim of the design

In this paper we outline the initial stages of a human centered design process aimed at the design of novel technology (tangible interactive objects) for stroke survivors. We found it useful to support standard methods, such as interviews and focus groups, with a video prototype in order to make the concept of tangible interaction, which was novel to our users, more clear. In addition we carried o

In contrast to the efficient market hypothesis (EMH), the noisy market hypothesis (NMH) asserts that prices are but noisy indications of fundamental values. The authors study losses in certainty equivalents of investing according to one hypothesis (NMH or EMH) when the other is true. Their findings suggest that, for reasonable parameter values, investing according to the EMH when the NMH is true y

There are several different preventive measures that can be used to reduce the number of fire fatalities in residential buildings, but information on how effective different measures are for different groups are, however, lacking. As a result, general measures are often implemented on large portions of the total population, which is not as cost-effective as targeting certain measures for certain g

Context Gestational diabetes is commonly linked to development of type 2 diabetes mellitus (T2DM). There is a need to characterize metabolic changes associated with gestational diabetes in order to find novel biomarkers for T2DM. Objective To find potential pathophysiological mechanisms and markers for progression from gestational diabetes mellitus to T2DM by studying the metabolic transition from

A collection of essays translated by Étienne Dobenesque.

A collection of unremarkably preserved fossil irregular echinoids from the Upper Oligocene (Chattian) Antigua Formation of Antigua, Lesser Antilles, nonetheless provides evidence of a range of palaeoecological interactions. A dead test of the heart urchin Eupatagus sp. formed a hard substrate for the attachment of gregarious Thecidellina? sp., a thecidoid brachiopod. Although obligate encrusters,

In a world careening towards climate chaos, nature is dead. It can no longer be separated from society. Everything is a blur of hybrids, where humans possess no exceptional agency that sets them apart from dead matter. But is it really so? In this blistering polemic and theoretical manifesto, Andreas Malm develops a contrary argument: in a warming world, nature comes roaring back, and it is more i

How can the realities of global warming be made visible in literary texts? After the rise of 'cli-fi', it might be time to return to a trove of literature written long before the discoveries of climate science: fiction about fossil fuels. It is filled with premonitions of disasters, such as extreme heat and terrible storms. Focusing on two texts - Ghassan Kanafani's Men in the Sun and Joseph Conra

Background Registry studies and case-control studies have demonstrated that the risk of acute myocardial infarction (AMI) is increased following influenza infection. Small randomized trials, underpowered for clinical end points, indicate that future cardiovascular events can be reduced following influenza vaccination in patients with established cardiovascular disease. Influenza vaccination is rec