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HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex

The basic helix-loop-helix (bHLH) transcription factor mammalian achaete-scute homolog-1 (MASH-1 in mouse and HASH-1 in human) is essential for proper development of olfactory and most peripheral autonomic neurons, and for the formation of distinct neuronal circuits within the central nervous system. We have previously shown that HASH-1 is expressed in neuroblastoma tumors and cell lines, and in t

Examining Pauses in Writing: Theory, Methods and Empirical Data

Abstract in UndeterminedThis chapter will address both theoretical and methodological issues in pause analysis. First, the theoretical assumptions concerning how pause analysis can contribute towards our understanding of written language production are discussed. Subsequently, some measures, methods and tools for automatic pause analysis are presented and some empirical analyses are given. Most of

Simulating the palaeorecord of northern European lakes using a coupled lake-catchment model

A coupled lake-catchment model was developed to examine the controls on lake-level changes in currently overflowing lakes during Holocene. The lake energy-balance is simulated as the one-dimensional vertical heat transfer by eddy diffusion and convective mixing. The accumulation and ablation of lake ice, and snow cover on the ice, is simulated thermodynamically. The lake water-balance is given by

Lack of relation between glycosylated haemoglobin concentrations and number of daily insulin injections: cross sectional study in care of ambulatory diabetes

Diabetic treatment aims at achieving a normal blood glucose concentration as reflected by the glycosylated haemoglobin concentration. Intensive treatment by insulin pump or multiple insulin injections is thought to achieve this. In an unselected group of outpatient diabetics metabolic control was the same after one, two, three, or more injections, which suggests that the mode of treatment was opti

Osseointegrated wrist-joint prostheses: A 15-year follow-up with focus on bony fixation.

Five patients with rheumatoid arthritis or osteoarthrosis of the wrist joint were followed up for 15 ( 14 - 17) years after wrist-joint arthroplasty with semiconstrained artificial joint mechanisms that had been anchored to bone using the osseointegration principle. They were fixed by one titanium screw introduced into the radius, and two or more titanium screws introduced distally into the metaca

Effects of Trichloroethylene inhalation on acid phosphatase in rodent brain

Rats, mice and gerbils were continuously exposed to 150 ppm trichloroethylene (TCE) for 30 days. In all three species, there was a marked increase in liver weight. In mice the weight increased more (86%) than in rats and gerbils (20%). After exposure the activity of acid phosphatase, a lysosomal marker enzyme, was tested in different brain areas, using a system which had a limit of detection of ±

Psychotropic drugs in nursing- and old-age homes: relationships between needs of care and mental health status

Objective: The aim of the present study was to map out what kind of psychotropic drugs are prescribed for elderly residents in assisted-living homes and how they relate to age, sex, form of living, psychiatric diagnosis, care needs and mental health status, and to identify factors of importance for their use; and to study the indication for treatment and the evaluation of the effects of treatment.

Long-term patterns of shifts between clear and turbid states in Lake Krankesjon and Lake Takern

During the past century, Lake Takern and Lake Krankesjon, southern Sweden, have shifted repeatedly between a state of clear water and abundant submerged vegetation, and a state of turbid water and sparse vegetation. Long-term empirical data on such apparently alternative stable state dynamics are valuable as complements to modeling and experiments, although the causal mechanisms behind shifts are

Trapping of microparticles in the near field of an ultrasonic transducer

We are investigating means of handling microparticles in microfluidic systems, in particular localized acoustic trapping of microparticles in a flow-through device. Standing ultrasonic waves were generated across a microfluidic channel by ultrasonic microtransducers integrated in one of the channel walls. Particles in a fluid passing a transducer were drawn to pressure minima in the acoustic field

Masses, lifetimes and production rates of Xi(-) and Xi(+) at LEP 1

Measurements of the Xi(-) and (Xi) over bar (+) masses, mass differences, lifetimes and lifetime differences are presented. The (Xi) over bar (+) sample used is much larger than those used previously for such measurements. In addition, the S production rates in Z -> b (b) over bar and Z -> q (q) over bar events are compared and the position xi* of the maximum of the distribution in Z -> q (q) over

Miljömålet i skogsbruket : Styrning och frivillighet

Popular Abstract in Swedish Införandet av 1993 års skogspolitiska beslut med ett jämställt miljö- och produktionsmål, belyser den historiskt befästa konflikten mellan allmänintresse och egenintresse: statens vilja och behov att styra produktion och avkastning kontra den enskilde skogsägarens rätt att själv bestämma över sin skog. Idag har denna konflikt styrt över mot en statligt uttalad målsättniThis dissertation analyzes the changes in the way Swedish forest policy has been developed and implemented in the past few decades. Its primary focus is on the period from the adoption of new legislation governing forestry in 1993 to date, though the historical antecedents of the more recent developments are also discussed. The dissertation focuses primarily on the interplay between changes in the

A calorimetric study of the gel-to-liquid crystal transition in catanionic surfactant vesicles

Dilute solutions of catanionic vesicles formed by the mixed single-chained (sodium dodecylsulphate, SDS) and double-chained (didodecyldimethylammonium bromide, DDAB) surfactants have been investigated by differential scanning calorimetry. It is for the first time reported a gel-to-liquid crystal phase transition temperature, T-m, in this type of mixed vesicles. The SDS-rich vesicles (at X-SDS = 0.