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Play and productivity : enhancing the creative climate at workplace meetings with play cues
The authors investigate the links between playfulness and creative organizational climates established by other research, using play cues—objects and sweets—they provide participants halfway through workplace meetings. Their findings suggest such cues significantly enhance the creative climate and playfulness in workplace meetings without risking meeting productivity. Key words: adult playfulness;
Characterization of hemicelluloses in process streams in thermomechanical and chemi-thermomechanical pulp mills
Increased interest in hemicelluloses as a renewable source of biopolymers has resulted in an interest in hemicelluloses in process streams in pulp mills. The aim of this study was to compare potential positions for the withdrawal of hemicelluloses from mechanical pulp mills. Samples were withdrawn at a total of fourteen positions from two thermomechanical and two chemi-thermomechanical pulp mills.
Sectoral co-movements of employment growth at regional level
This paper presents a comprehensive study of sectoral co-movements of employment growth in the entire Dutch economy. We construct different macro typologies according to manufacturing versus services, innovativeness, labour skills and position in the value chain, thus expanding the list of potential logics of sectoral interrelations. Using a vector autoregression model, we assess whether and how g
Leadership in opera : Romance, betrayal, strife and sacrifice
What, if anything, does opera tell us about leadership, leaders and followers, that social research or indeed other art forms do not tell us? This is the question I address here. I argue that opera is a highly political genre, able to depict political events involving leaders and followers in sharply illuminating ways. In particular, through the device of the chorus it is able to represent the pol
Cutting edge : Evidence of direct TCR α-chain interaction with superantigen
Superantigens are known to activate a large number of T cells. The SAg is presented by MHC class II on the APC and its classical feature is that it recognizes the variable region of the β-chain of the TCR. In this article, we report, by direct binding studies, that staphylococcal enterotoxin (SE) H (SEH), a bacterial SAg secreted by Staphylococcus aureus, instead recognizes the variable α-chain (T
Exceptional overproduction of a functional human membrane protein
Eukaryotic-especially human-membrane protein overproduction remains a major challenge in biochemistry. Heterologously overproduced and purified proteins provide a starting point for further biochemical, biophysical and structural studies, and the lack of sufficient quantities of functional membrane proteins is frequently a bottleneck hindering this. Here, we report exceptionally high production le
High-level bacterial secretion of single-chain αβ T-cell receptors
While numerous antibody-antigen systems have been structurally characterized, studies of structurally analogous T-cell receptor MHC systems have lagged behind largely due to the lack of a general TCR expression system. Efforts to develop bacterial systems have resulted in low yields (< 0.5 mg/l) of active material which is prone to proteolysis and aggregation. Here we report a strategy to secrete
Structure of an autoimmune T cell receptor complexed with class II peptide-MHC : Insights into MHC bias and antigen specificity
T cell receptor crossreactivity with different peptide ligands and biased recognition of MHC are coupled features of antigen recognition that are necessary for the T cell's diverse functional repertoire. In the crystal structure between an autoreactive, EAE T cell clone 172.10 and myelin basic protein (1-11) presented by class II MHC I-Au, recognition of the MHC is dominated by the Vβ domain of th
Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence
The three-dimensional structure of a bacterial superantigen, Staphylococcus aureus enterotoxin H (SEH), bound to human major histocompatibility complex (MHC) class II (HLA-DR1) has been determined by X-ray crystallography to 2.6 Å resolution (1HXY). The superantigen binds on top of HLA-DR1 in a completely different way from earlier co-crystallized superantigens from S. aureus. SEH interacts with h
The geography and structure of Global Innovation Networks : global scope and regional embeddedness
The chapter discusses the spatial aspects of the increased globalization of innovation, analysing both the region’s role in influencing the propensity of actors to engage and to play different roles in global innovation networks (GINs). Until now, different concepts such as global value chain (GVC), global production network (GPN) and GIN have been used to explain the increase globalization of inn
Does institutional diversity promote global innovation networks?
Recent literature stresses the increasing importance of global innovation networks as a new mechanism to organize innovation across geographical space. This paper investigates if institutional diversity, defined at the level of the firm, influences firms’ engagement in GINs. Institutional diversity provides knowledge about the institutional context of other countries, increased capabilities to dea
Ideological friction and political crisis : Queen Luise Ulrike of Sweden and a failed coup d’état
Leadership Ideals as Barriers for Efficient Collaboration During Emergencies and Disasters
In an emergency or disaster situation, it is likely that a conglomerate of societal resources will respond to various needs. In such a multi-organizational setting, collaboration becomes necessary. Empirical findings suggest that collaboration can be very problematical and this paper argues that a possible explanation can be found in intra-organizational leadership ideals, dysfunctional in a colla
Perturbations of embedded eigenvalues for a magnetic Schrödinger operator on a cylinder
Perturbation problems for operators with embedded eigenvalues are generally challenging since the embedded eigenvalues cannot be separated from the rest of the spectrum. In this paper, we study a perturbation problem for embedded eigenvalues for a magnetic Schrödinger operator, when the underlying domain is a cylinder. The magnetic potential is C2 with an algebraic decay rate as the unbounded vari
Directional interpolation of multicomponent data
A method for interpolation of multicomponent streamer data based on using the local directionality structure is presented. The derivative components are used to estimate a vector field that locally describes the direction with the least variability. Given this vector field, the interpolation can be phrased in terms of the solution of a partial differential equation that describes how energy is tra
Thermodynamical string fragmentation
The observation of heavy-ion-like behaviour in pp collisions at the LHC suggests that more physics mechanisms are at play than traditionally assumed. The introduction e.g. of quark-gluon plasma or colour rope formation can describe several of the observations, but as of yet there is no established paradigm. In this article we study a few possible modifications to the Pythia event generator, which
C2 Fracture Subtypes, Incidence, and Treatment Allocation Change with Age : A Retrospective Cohort Study of 233 Consecutive Cases
The currently available data on the distribution of C2 fracture subtypes is sparse. This study was designed to identify the proportions of the second cervical vertebra (C2) fracture subtypes and to present age and gender specific incidences of subgroups. A dataset of all patients treated between 2002 and 2014 for C2 fractures was extracted from the regional hospital information system. C2 fracture