The importance of the N-terminal region of human cystatin C or chicken cystatin for the kinetics of interactions of the inhibitors with four cysteine proteinases was characterized. The association rate constants for the binding of recombinant human cystatin C to papain, ficin, actinidin and recombinant rat cathepsin B were 1.1 x 10(7), 7.0 x 10(6), 2.4 x 10(6) and 1.4 x 10(6) M-1.s-1, whereas the

AIMS: An increased risk for Type 2 diabetes in male and female smokers has been associated with insulin resistance. However, this might also be the result of an adverse effect on the beta-cell. The aim of the present study was to examine the association between smoking and beta-cell function. METHODS: A community-based, cross-sectional observation study. In 1994, a randomized age-stratified sample

The results of primary hip replacements are good. However, dealing with a loose prosthesis has been problematic, especially when major bone deficiencies are encountered. These problems appear to have been solved by the introduction of the Slooff-Ling method of using morselized and impacted allograft chips. The clinical results are excellent in the hands of the innovators. However, it remains confu

Restrictions of what is in first position in a Swedish declarative clause are usually textual or pragmatic, very seldom grammatical. In this paper I discuss one case of this type, the fact that the indirect object cannot be in sentence initial position in passive of ditransitive verbs where the DP corresponding to the direct object has been promoted to subject, as in (i): (1) *Johan har det här jo

Objective To explore the feasibility of retroviral-mediated Flt 3 ligand (FL) and thrombopoietin (Tpo) genes transferred into and expressed in a bone marrow stromal cell line HFCL by internal ribosome entry site（IRES）sequence. Methods IRES sequence, FL and Tpo cDNA were recombined with retroviral vector pLXSN by gene recombination technology. The recombinant plasmid was transferred into retrovirus

Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO). Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event. Resu

A molecularly imprinted polymer was prepared using tert-butyloxycarbonyl-L-phenylalanine as the print molecule and methacrylic acid as the functional monomer. The bulk polymer obtained was ground, sieved, packed into a column and investigated in the HPLC-mode by frontal chromatography to determine the number of binding sites and dissociation constants for the enantiomers interacting with the polym

The overarching aim of this thesis is to study the long term effects of a voluntary speed adaptation system, the Active Accelerator Pedal (AAP), and its effectiveness for different driver types. The papers making up this thesis are based on a study carried out on 284 vehicles and drivers in the Swedish city of Lund from 1999 until 2002. The results showed that the AAP brought a significant reducti

To assess the stability of polyomavirus antibodies in serial samples over time and the incidence and age-specific prevalence of polyomavirus infections, we established enzyme immunoassays (EIAs) using purified yeast-expressed virus-like particles (VLPs) containing the VP1 major capsid proteins of JC virus (JCV) and the AS and SB strains of BK virus (BKV). A random subsample of 150 Finnish women wh

De grundläggande åldringsfaktorernas inverkan på vanliga typer av fogmassor. Samband mellan accelererade åldringsmetoder och naturlig åldring.

PURPOSE: To investigate the correlation of estrogen receptor (ER) gene polymorphism to dry eye syndrome in postmenopausal women. METHODS: Xba I and Pvu II polymorphism of ER gene were studied by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 65 patients with dry eye syndrome and 73 with controls in postmenopausal women. RESULTS: There was a significant difference

The main objective of this PhD thesis, "An Aesthetics of Sexual Difference? On Art and Artistry in Swedish Handicraft of the 1920s and 1990s", is to investigate the field of handicraft in relation to a wider field of cultural production. Its aim is to contribute to a mapping of interrelated outlines of handicraft and art based on empirical studies of artistic creation in two local Swedish handicra

Popular Abstract in SwedishAvhandlingen syftar till att studera svenska föreställningar om USA och det amerikanska och genom dem den svenska självbilden och olika visioner om den svenska framtiden i den offentliga debatten under perioden c:a 1900-1939, då USA var omdiskuterat som en mycket betydelsefull ny nation men ännu inte erkänt som en obestridlig supermakt. Den söker visa hur föreställningarThe aim of this thesis is to study Swedish notions of the USA and of things American and through them the Swedish self-image and the ideas about the Swedish future as seen in public debate in the period c. 1900-1939, when the USA was the subject of a good deal of discussion as an up-and-coming nation of great importance but was not yet recognized as an indisputable super power. It tries to demonst

The phylogenetic relationships of the lichenised ascomycete family Stereocaulaceae were investigated with partial beta-tubulin, partial glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and SSU rDNA sequence data. Due to the marked length variation in the SSU rDNA sequences, the analyses were performed with direct optimization. The combined analysis of the beta-tubulin, GAPDH and SSU rDNA sequences

Popular Abstract in Swedish Syftet med denna studie är att förbättra den nuvarande svenska konflikttekniken [TCT] inom området fordon - fotgängarekonflikter. Den nuvarande definitionen av konflikters allvarlighetsgrad verkar ge färre allvarliga konflikter än den borde, särskilt när den relevanta trafikanten (RRU) är en fotgängare. Ett annat mål är att tillämpa den svenska konflikttekniken i JordanThis study is aimed at improving the current Swedish Traffic conflicts Technique [TCT] in relation to vehicle-pedestrian conflicts. The present definition of conflict severity appears to produce less severe conflicts than they might be, particularly if the relevant road user (RRU) is the pedestrian. Another aim is to apply the Swedish TCT in Jordan as a method for evaluating safety conditions at j

We present and analyze low-rank channel estimators for orthogonal frequency-division multiplexing (OFDM) systems using the frequency correlation of the channel. Low-rank approximations based on the discrete Fourier transform (DFT) have been proposed, but these suffer from poor performance when the channel is not sample spaced. We apply the theory of optimal rank-reduction to linear minimum mean-sq

This paper reports on a novel design for a high-brightness quantum-well AlGaInP laser-diode system operating at 635 nm. The spatial coherence of two broad area laser diodes is improved using spatial filtering and optical feedback from a narrow mirror stripe on each laser. To increase power, the outputs from the two systems are passively combined using a polarizing beam splitter. The result is a co