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Modelling of molybdopterin-dependent enzymes

Popular Abstract in Swedish Molybden ingår som en viktig del i två typer av biologiska system - dels i nitrogenas, som fixerar kvävgas ur atmosfären, och dels i de enkärniga molybdenenzymerna. De senare är enzymer som innehåller endast en molybdenatom i sina aktiva säten. De enkärniga molybdenenzymerna finns i en mängd levande system, från bakterier till växter och djur och även i människan. EnzymThe thesis deals with models for molybdopterin-dependent enzymes. Several model systems containing molybdenum or tungsten have been prepared and characterised, and their reactivity with oxygen atom acceptors and donors have been investigated. Oxygen atom transfer reactions involving oxomolybdenum bis-dithiolene complexes have been modelled using density functional calculations. The first molybden

Clinical and experimental studies in corticosteroid contact allergy

Popular Abstract in Swedish Kliniska och experimentella studier av kortisonallergi Kortisonämnen har använts sedan 1950 talets början för att behandla olika hudsjukdomar såsom eksem och psoriasis. Redan 1959 kom de första rapporterna om kontaktallergi mot hydrokortison, ett kroppseget kortisonämne. Senare studier har visat att 4–5 % av alla patienter som allergitestas med så kallat lapptest (epikuCorticosteroids are anti-inflammatory and anti-proliferative substances that also can induce sensitization, mainly through skin contact. In a sensitized individual, it can be hard to disclose the contact allergy at patch testing because the anti-inflammatory effect may mask the allergic contact reaction. This is primarily seen when patch testing to potent corticosteroids is performed and the readi

Adaptive Control (2 rev. Dover ed.)

Suitable for advanced undergraduates and graduate students, this overview introduces theoretical and practical aspects of adaptive control. It presents an excellent perspective on techniques and an active knowledge of key approaches, offering a well-developed sense of when to use adaptive techniques and when other methods are more appropriate. 1995 edition.

Investigation of image components affecting the detection of lung nodules in digital chest radiography

The aim of this work was to investigate and quantify the effects of system noise, nodule location, anatomical noise and anatomical background on the detection of lung nodules in different regions of the chest x-ray. Simulated lung nodules of diameter 10 mm but with varying detail contrast were randomly positioned in four different kinds of images: 1) clinical images collected with a 200 speed CR s

Expression of Islet Amyloid Polypeptide - Localization and regulation in the pancreatic islets, gastrointestinal tract and sensory nervous system.

Popular Abstract in Swedish Därför får man sockersjuka (Felix Mulder, 6 år): ”Det är inte bra att äta för mycket socker. Socker är vasst och skär sönder blodkropparna. Då kan man inte göra insulin och man blir sjuk.” Islet amyloid polypeptide (förkortat: IAPP) är ett medelstort äggviteämne - peptid - som upptäcktes 1986 av Per Westermark i Uppsala. Denna upptäckt har en intressant bakgrund. Det hIslet amyloid polypeptide (IAPP; also named ”amylin”) is a member of the calcitonin superfamily of peptides, displaying the closest structural relationship to the neuropeptide calcitonin gene-related peptide (CGRP). It is expressed in islet beta-cells and forms islet amyloid in type 2 diabetic patients. IAPP may restrain release and peripheral actions of insulin. Thus, IAPP has been implicated in

The Rhythm of the Unit Is the Pace of Life: A Study of Everyday Activities and Sleep in Swedish Residential Care

Social and physical activities can improve sleep in older people. However, living in a residential care facility has been associated with a limited potential for activities and increased inactivity, reflected in poor sleep among residents. In turn, poor sleep can impair physical and mental functions. This paper explores sleep habits and everyday activities at three residential care facilities and

Solar radiation effects on decomposition and decomposers of plant litter in lakes

This thesis summarizes the results of a series of experiments, from test tube up to field study scale, performed to increase the understanding of solar radiation effects on decomposition and microbial decomposers of plant litter in stagnant water of littoral zones. In conclusion, I suggest that fungi play a significant role in the decomposition of plant litter submersed in lakes, and that their d