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Health Economic Analysis of Open and Robot-assisted Laparoscopic Surgery for Prostate Cancer Within the Prospective Multicentre LAPPRO Trial

Background: The rapid adoption of robot-assisted laparoscopy in radical prostatectomy has preceded data regarding associated costs. Qualitative evidence regarding cost outcomes is lacking. Objective: This study assessed how costs were affected by robot-assisted laparoscopic prostatectomy (RALP) compared with open surgery. Design, setting, and participants: Cost analysis was based on the dataset of

Cultivating a sustainable society : attempts to change contemporary Sweden by urban gardening and theatre

In this presentation, we discuss how projects use theatre and urban gardening as tools to handle and promote cultural diversity in Sweden. Our presentation build on data collected during the last decade in Malmö, a city characterised by immigration, super-diversity and a post-industrial economy. The projects we have studied are often short term and dependent on uncertain, external funding. The tar

Development and Validation of a Questionnaire to Measure Patient's Experiences of Health Care in Pulmonary Arterial Hypertension Outpatient Clinics

Background: Measuring the patients’ experience of care at an outpatient clinic can provide feedback about the quality of health care and if needed, can be support for quality improvements. To date, there is no patient reported experience measurement (PREM) developed targeting patients at the pulmonary arterial hypertension (PAH) outpatient clinics. Therefore, the aim was to develop and evaluate th

Biodegradation of 17-β-estradiol in water

This study reports a potential biotechnical method of 17-β-estradiol removal in aquatic systems. The different bacterial strains isolated from sewage water samples were Bacillus sp., Enterobacter sp. I, Enterobacter sp. II, Klebsiella sp., Aeromonas veronii and Aeromonas punctate. These isolates were characterized on the basis of a single PCR reaction from the 5′ end of the PCR fragment to obtain

mHTT Seeding Activity : A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease

Self-propagating, amyloidogenic mutant huntingtin (mHTT) aggregates may drive progression of Huntington's disease (HD). Here, we report the development of a FRET-based mHTT aggregate seeding (FRASE) assay that enables the quantification of mHTT seeding activity (HSA) in complex biosamples from HD patients and disease models. Application of the FRASE assay revealed HSA in brain homogenates of presy

Thermoelectric experiments on nanowire-based quantum dots

This thesis experimentally investigates the possibilities of using quantum effects in semiconductor nanostructures for engineering their thermoelectric properties. More specifically, heterostructured InAs/InP nanowires are used to create short InAs quantum dots (QDs) with electronic state structure resembling that found in atoms. Recently developed top-heater architecture is used to apply a temper

Predicting bond betas using macro-finance variables

We predict bond betas conditioning on a number of macro-finance variables. We explore differences across long-term government bonds, investment grade corporate bonds, and high yield corporate bonds. We conduct out-of-sample forecasting using the new approach of combining predictor variables through complete subset regressions (CSR). We consider the robustness of CSR forecasts across the 1-month, 3

Bleeding Events After ST-segment Elevation Myocardial Infarction in Patients Randomized to an All-comer Clinical Trial Compared With Unselected Patients

Most studies reporting bleedings in patients with ST-segment elevation myocardial infarction (STEMI) are reports from clinical trials, which may be unrepresentative of incidences in real-life. In this study, we investigated 1-year bleeding and mortality incidences in an unselected STEMI population, and compared participants with nonparticipants of a randomized all-comer clinical trial (The Third D

Translation and cultural adaptation of the CLEFT-Q into Arabic, Dutch, Hindi, Swedish, and Turkish

Background: Treatment for cleft lip and/or palate (CL/P) involves a multidisciplinary team of experts who aim to improve ones’ appearance, health-related quality of life, and speech function. To appropriately measure outcomes in CL/P from the patient perspective, a CL/P-specific patient-reported outcome (PRO) instrument is needed. The CLEFT-Q is a self-report PRO instrument developed to evaluate t

Mapping the Milky Way disc kinematics

Context. The second Gaia data release (Gaia DR2) contains high-precision positions, parallaxes, and proper motions for 1.3 billion sources as well as line-of-sight velocities for 7.2 million stars brighter than GRVS = 12 mag. Both samples provide a full sky coverage. Aims. To illustrate the potential of Gaia DR2, we provide a first look at the kinematics of the Milky Way disc, within a radius of s

Observations of solar system objects

Context. The Gaia spacecraft of the European Space Agency (ESA) has been securing observations of solar system objects (SSOs) since the beginning of its operations. Data Release 2 (DR2) contains the observations of a selected sample of 14,099 SSOs. These asteroids have been already identified and have been numbered by the Minor Planet Center repository. Positions are provided for each Gaia observa

Programmable controllers

Programmable logical controllers (PLCs) have been in use since the 1960s and are still the basis for the low-level control in many automation systems. Today PLCs can handle not only the lowest levels of control but also advanced control of hybrid systems, where time-driven continuous controllers have to be integrated with event-driven controllers. The state concept is of fundamental importance to

Membrane processes for sugar and starch processing

Sugars and starches belong to the category of carbohydrates, which are important energy sources for organisms and nonessential nutrients in the human diet. Sugars are mono- or disaccharides that can be immediately transformed to energy by organisms. Starches, on the other hand, are polysaccharides, a space-efficient storage of energy for organisms. Before transforming polysaccharides into energy f

Membrane separation processes an overview

The food industry, which is a major worldwide industry, is going through a revolution. Changing lifestyles and expectations, such as demand for fewer additives, have placed new demands on the industry, which can only be met by new technology. At the same time, the producers in this very large industry have a further challenge, namely, that of the countervailing power of the retailer. Some years ag

Engineering aspects of membrane separation and application in food processing

Engineering Aspects of Membrane Separation and Application in Food Processing presents an overview and introduction to a wide range of membrane processes, their unique characteristics and challenges. In the food industry, as in many industries, membranes have an environmental advantage over conventional processes that they displace, because they are less energy intensive. The processing at near-am