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Tumour location and axillary lymph node involvement in breast cancer: a series of 3472 cases from Sweden.
Health-related quality of life of patients with implantable cardioverter defibrillators compared with that of pacemaker recipients
AIMS: Studies indicate a poorer quality of life (QoL) for implantable cardioverter defibrillator (ICD) patients than for the general population. However, studies comparing the QoL of ICD patients with that of patients with other implantable cardiac devices are scarce. We hypothesized that ICD patients had a poorer QoL than pacemaker patients. METHODS AND RESULTS: All ICD patients living in Iceland
Explanatory and Non-Explanatory Goals in Social Science
Multilevel analytical approaches in social epidemiology: measures of health variation compared with traditional measures of association.
Studies of chronic ITP in children and adolescents.
This paper presents an ongoing study of children with chronic ITP in Sweden that addresses four specific questions: is there a subgroup of children with chronic ITP that have impaired platelet function? Do children in this subgroup have antibodies directed against surface glycoproteins that are crucial for platelet function? Can desmopressin improve the impaired platelet function in this subgroup?
Micturition problems in relation to quality of life in men with prostate cancer or benign prostatic hyperplasia - Comparison with men from the general population
The aim of the study was to investigate men with prostate cancer and benign prostatic hyperplasia (BPH) in comparison with men from the general population in aspects of presence and frequency of micturition problems in remembrance of prior to treatment and currently. Further, the aim was to investigate the impact of micturition problems on quality of life and the association with micturition probl
Diplomatic Signalling in the Television Age
To what extent does television interfere with and complicate diplomatic signaling via other channels? Conversely, to what extent can world leaders and diplomats use television to their advantage? Exploring these questions, this article focuses on the combination of communication speed and excitable public opinion, on the one hand, and the metaphorical and symbolic aspects of the medium, on the oth
Single point extremal functions in Bergman-type spaces
Let A be a zero sequence for the Bergman space L-a(2) of the unit disc D, and let phi(A) be the corresponding canoniacal zero divisor. In this paper we consider quotients of the type phi(Au {alpha})/phi(A), alpha is an element of D. By use of methods from the theory of reproducing kernels we shall show that the modulus of such functions is always bounded by 3, and that they can be written as a pro
Nanoimprinted passive optical devices
We report on the feasibility and process parameters of nanoimprint lithography to fabricate low refractive index passive optical devices. Diffraction gratings printed in polymethylmethacrylate (PMMA) exhibit a sharp dispersion with a full width at half maximum of about 20 nm. Waveguides were printed in polystyrene (PS) on silicon oxide and had losses between 8-20 dB cm(-1) at wavelengths between 6
Precipitation by polycation as capture step in purification of plasmid DNA from a clarified lysate
The demand for highly purified plasmids in gene therapy and plasmid-based vaccines requires large-scale production of pharmaceutical-grade plasmid. Large-scale purification of plasmid DNA from bacterial cell culture normally includes one or several chromatographic steps. Prechromatographic steps include precipitation with solvents, salts, and polymers combined with enzymatic degradation of nucleic
Education for Democracy : Some Notes on the Swedish Case in a Piagetian Epistemology Tradition
Almost all Swedish politicans since 1960 honestly believe in the necessity to give pupils real influence over their schools. The first aim with this paper is to give them some sound theoretical support for their conviction that experience of democratic processes is one important precondition for the survival of democracy. The theoretical support is drawn from researchers inspired by Piaget's epist
Dimension splitting for evolution equations
In this paper, we are concerned with splitting methods for the time integration of abstract evolution equations. We introduce an analytic framework which allows us to prove optimal convergence orders for various splitting methods, including the Lie and Peaceman–Rachford splittings. Our setting is applicable for a wide variety of linear equations and their dimension splittings. In particular, we an
An alkaline active xylanase: Insights into mechanisms of high pH catalytic adaptation.
The alkaliphilic bacterium, Bacillus halodurans S7, produces an alkaline active xylanase (EC 3.2.1.8), which differs from many other xylanases in being operationally stable under alkaline conditions as well as at elevated temperature. Compared to non-alkaline active xylanases, this enzyme has a high percent composition of acidic amino acids which results in high ratio of negatively to positively c
Asthma quality of life during 1 year of treatment with budesonide with or without formoterol
The Formoterol and Corticosteroids Establishing Therapy (FACET) study has provided the first opportunity to examine the long-term effects of inhaled steroids and long-acting beta2-agonists on asthma-specific quality of life. The objectives of the present study were to: evaluate the effects of long-term (1 yr) formoterol and increasing doses of budesonide on asthma quality of life; 2) to determine
''Sponge" nanoparticle dispersions in aqueous mixtures of diglycerol monooleate, glycerol dioleate, and polysorbate 80
Lipid nanoparticles of nonlamellar lyotropic phases have a wide solubilizing and encapsulating spectrum for a range of substances thanks to their nanostructured interior featuring both lipophilic and hydrophilic domains. As a consequence, these systems have emerged as promising drug delivery systems in various pharmaceutical and diagnostic applications. Here we present the phase behavior and dispe
Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis
Objective. To examine synovial fluid as a site for generating citrullinated antigens, including the candidate autoantigen citrullinated alpha-enolase, in rheumatoid arthritis (RA). Methods. Synovial fluid was obtained from 20 patients with RA, 20 patients with spondylarthritides (SpA), and 20 patients with osteoarthritis (OA). Samples were resolved using sodium dodecyl sulfate-polyacrylamide gel e
Comparative chemical and biological characterization of the lipopolysaccharides of gastric and enterohepatic helicobacters
Background. The lipopolysaccharide of Helicobacter pylori plays an important role in colonization and pathogenicity. The present study sought to compare structural and biological features of lipopolysaccharides from gastric and enterohepatic Helicobacter spp. not previously characterized.Materials and methods. Purified lipopolysaccharides from four gastric Helicobacter spp. (H. pylori, Helicobacte
Wingless, hedgehog and heparan sulfate Proteoglycans
Compatibility between Flooring Materials and Concrete
This article outlines an experimental and numerical study on compatibility between flooring materials and concrete. Full-scale cylinders and slabs with different kinds of floorings were tested. The cylinders were studied in the laboratory, and cured in the same way as at a building site. The slabs were ground, treated with plaster and/or untreated (reference concrete). These slabs were water-cured