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Calcitonin gene-related peptide (CGRP) is expressed throughout the CNS and peripheral nervous system, consistent with control of vasodilatation, nociception, motor function, secretion and olfaction. alphaCGRP is prominently localized in primary afferent C and Adelta fibres of spinal and trigeminal ganglia. Activation of the trigeminal nerve results in antidromic release of CGRP, acting through a C
Kostnaderna för att åtgärda fukt- och vattenskador i våra våtrum har ökat dramatiskt och oroväckande under senare år. I den skadeinventering som ingick i SABOs stora projekt 'Fukt och mögel i flerbostadshus' uppvisade 11,3 procent av våtrummen skador av olika slag
The aim of this project has been to study timber house manufacturers and provide guidance to those who aim to increase efficiency through the adaption of product modeling and eventually configuration. The findings in this report are based on a series of case studies within the abovementioned industry, which serves as a basis for the analysis and recommendations given. The Swedish timber house man
This paper discusses the evolutionary function of certain advanced aspects of cognition, like planning, self-awareness, and free will. The inner environment of an agent consists of all representations which the agent can actively "think about". A distinction is made between immediate planning, where plans are made for present needs, and anticipatory planning, where future needs are predicted. Huma
Dating the transgression and subsequent regression in marginal basins of the southeastern Swedish Baltic Sea provides a new perspective of global ice-volume changes and the isostatic adjustment of the mantle after the retreat of the Scandinavian Ice Sheet from this area. Superimposed upon a smooth pattern of local sea-level rise, acceleration occurred ca. 7600 calibrated (cal) yr B.P., evidenced a
Vitrectomy requires the substitution of the natural vitreous, as well as tamponading of retinal breaks. Clinically available alternatives such as gas and silicone oil have side effects such as inflammation, secondary glaucoma, cataract, and a need for head posturing. In this study, a hydrogel of cross-linked sodium hyaluronic acid (Healaflow(®)) is evaluated for use as a novel vitreous substitute.
Mid-nineteenth-century Britain saw a significant output of fictional texts, conduct books and tracts with an explicit focus on the concept of punctuality. This article examines a number of such texts by linking the notion of punctuality to the general nineteenthcentury wish for self-improvement and social progress. Three central facets of midnineteenth-century punctuality are identified and discus
LMO2, a member of the LIM-only protein family, is essential for the regulation of hematopoietic stem cells and formation of erythroid cells. It is found in a transcriptional complex comprising LMO2, TAL1, E47, GATA-1, and LDB1 which regulates erythroid genes. While TAL1 has been shown to induce erythroid differentiation, LMO2 appears to suppress fetal erythropoiesis. In addition to LMO2, the close
