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Ethanol intake and risk of lung cancer in the European prospective investigation into cancer and nutrition (EPIC)

Within the European Prospective Investigation into Cancer and Nutrition (EPIC), the authors examined the association of ethanol intake at recruitment (1,119 cases) and mean lifelong ethanol intake (887 cases) with lung cancer. Information on baseline and past alcohol consumption, lifetime tobacco smoking, diet, and the anthropometric characteristics of 478,590 participants was collected between 19

Multicast routing for ad hoc networks with a multiclass scheme for quality of service

As multimedia- and group-oriented computing becomes increasingly popular for the users of wireless mobile networks, the importance of features like quality of service (QoS) and multicasting support grows. Ad hoc networks can provide users with the mobility they demand, if efficient QoS multicasting strategies are developed. The ad hoc QoS multicasting (AQM) protocol achieves multicasting efficienc

Intraoperative proximal endoleaks during AAA stent-graft repair: evaluation of risk factors and treatment with Palmaz stents

PURPOSE: To study factors that might contribute to intraoperative proximal type I endoleak and to evaluate the placement of giant Palmaz stents as a therapeutic option. METHODS: Thirty-three patients (30 men; median age 72 years, range 50-85) with abdominal aortic aneurysms underwent implantation of fully supported Gianturco Z-stent-based endografts (12 custom-made aortomonoiliac and 21 bifurcated

Transformation to a customer-oriented perspective through action learning in product and service development

Customer orientation is strongly visible in the visions and strategies of most organizations, but how do these visions and strategies move from intentions to practice? This question provides the focus for this research which aims to acquire deeper insights into this process. The point of departure is the change in perspective from a product to a customer orientation in product and service developi

The influence of personality traits on neuropsychological test performance and self-reported health and social context in women

The relationship between on the one hand personality traits and, on the other hand, neuropsychological test performance, self-rated distress symptoms, psychosocial work exposure, and social interaction patterns, was studied in a group of healthy women (N= 101). All subjects completed the Karolinska Scales of Personality inventory (KSP) and the majority of the subjects (n = 88) completed the State

Geometric scaling and QCD dynamics in DIS

DIS data from HERA show a striking regularity as sigma(gamma*p) is a function of the ratio tau = Q(2)/Q(s)(2)(x) only. The scaling function shows a break at 7 t, which has been taken as an indication for saturation. However, besides saturation also the transition between dominance of k(perpendicular to)-ordered (DGLAP) and k(perpendicular to)-non-ordered (BFKL) evolution contributes to a break aro

A generic surface modification strategy for sensing applications based on Au/SiO2 nanostructures

A generic protocol for the creation of material-mediated self-assembled patterns of streptavidin, defined solely by patterns of gold and SiO2, is presented. Protein-adsorption resistance of selected regions was obtained by material-specific adsorption of thiol-modified poly(ethylene)glycol (thiol-PEG) on gold followed by adsorption of poly-L-lysine (PLL) modified PEG (PLL-g-PEG) on SiO2. Selective

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat

The immunosuppressant drug cyclosporin A (CsA) is considered to be inherently protective in conditions of ischemia, e.g. in hepatic and cardiac tissue. However, investigations of effects of CsA on neuronal tissue have been contradictory, probably because the blood-brain barrier (BBB) is virtually impermeable to CsA. In the present study, we exploited the finding that the insertion of a syringe nee

Cholesterol Dependence of Vascular ERK1/2 Activation and Growth in Response to Stretch. Role of Endothelin-1.

Objective— Stretch-induced growth of the vascular wall plays a role in hypertension and neointima formation. Its signal pathways involve integrins, cytoskeleton, membrane receptors, and ion channels, some of which are organized in cholesterol-rich, membrane domains such as lipid rafts or caveolae. This study tested the role of rafts/caveolae in stretch-induced vascular growth by manipulation of me

Ionic charge, radius, and potential control root/soil concentration ratios of fifty cationic elements in the organic horizon of a beech (Fagus sylvatica) forest podzol

The root/organic soil concentration ratio; R/S) of 50 cationic mineral elements was related to their ionic properties, including ionic radius (r), ionic charge (z), and ionic potential (z/r or z(2)/r). The materials studied were ectomycorrhizal beech (Fagus sylvatica L.) roots and their almost purely organic soil substrate, the O-horizon (mor; raw humus) of a Podzol in South Sweden, developed in a

Effect of SpeB and EndoS from Streptococcus pyogenes on human immunoglobulins

Streptococcus pyogenes secretes a specific immunoglobulin G (IgG)-protease, SpeB, as well as the IgG glycan-hydrolyzing enzyme EndoS. Here we show that SpeB also degrades IgA, IgM, IgD, and IgE. We also show that EndoS only hydrolyzes the glycan moiety on native but not denatured IgG. Thus, SpeB has a broad immunoglobulin-degrading activity, while EndoS is highly specific for IgG.

Cloud microphysics, radiation and vertical velocities in two- and three-dimensional simulations of deep convection

This study investigates the importance of dimensionality for the characteristics of simulations performed with cloud-system resolving models (CSRMs). In addition to intrinsic questions related to dimensionality in CSRMs, the issue has gained added interest since CSRMs can be utilized instead of conventional cloud parametrizations to represent deep convection within global climate models. Such CSRM

Influence of morphological and conformational changes on the molecular mobility in poly(ethylene naphthalene-2,6-dicarboxylate)

Dynamic electric (DEA) and mechanical (DMA) analyses were combined to explore the relaxational processes in amorphous and semicrystalline poly(ethylene naphthalene-2,6-dicarboxylate) (PEN) samples. Differential scanning calorimetry measurements were carried out to investigate the crystallinity of the samples following isothermal annealing treatment at 443 K. The two secondary relaxations beta and

Congenital malformations in infants whose mothers reported the use of folic acid in early pregnancy in Sweden. A prospective population study

The use of folic acid prior to conception is generally recommended for the prevention of birth defects, notably neural tube defects. In a previous study from Sweden, based on interviews of women in early pregnancy, no such effect was found on the general malformation rate, but data for neural tube defects were scarce. Using data from the Swedish Medical Birth Register for the years 1995-2004, 20 8

Multi-model statistical process monitoring and diagnosis of a sequencing batch reactor

Biological processes exhibit different behavior depending on the influent loads, temperature, microorganism activity, and soon. It has been shown that a combination of several models can provide a suitable approach to model such processes. In the present study, we developed a multiple statistical model approach for the monitoring of biological batch processes. The proposed method consists of four

Stability of the mercaptobenzothiazole compounds

An analytical quantitative high-pressure liquid chromatography (HPLC) method was developed for simultaneous determination of all mercaptobenzothiazole derivatives in the mercapto mix patch testing standard. The stability of the mercaptobenzothiazoles constituting the mercapto mix was studied both in petrolatum and in buffer solution at pH 6.5, with and without glutathione. In petrolatum vehicle, d