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Linear analysis solves two puzzles in population dynamics : the route to extinction and extinction in coloured environments

In this paper, we give simple explanations to two unsolved puzzles that have emerged in recent theoretical studies in population dynamics. First, the tendency of some model populations to go extinct from high population densities, and second, the positive effect of autocorrelated environments on extinction risks for some model populations. Both phenomena are given general explanations by simple, l

Cystine analyses of separate day and night urine as a basis for the management of patients with homozygous cystinuria

Based on previous observations of the diurnal variation of urinary cystine excretion, the use of separate day and night urine collections was proposed. To improve the medical treatment of patients with cystinuria, this strategy was performed to guide the fluid intake and the administration of SH compounds (tiopronin, D-penicillamine, and MESNA).Twenty-six patients (19 treated with SH compounds and

Normalization of haemoglobin concentration with recombinant erythropoietin has minimal effect on blood haemostasis

BACKGROUND: Elevation of haemoglobin (Hb) with recombinant erythropoietin (rHuEpo) in patients with chronic renal failure has raised concern of increased risk of thromboembolic diseases. In this study, a substudy of the Scandinavian multicentre trial, we examined the influence on haemostatic parameters of normalization of Hb levels from subnormal levels in patients with chronic renal failure.METHO

Renovascular disease and renal insufficiency--diagnosis and treatment

Renovascular disease as cause of end-stage renal disease has become more frequent during the last decade. In order to minimize the need for dialysis treatment non-invasive screening for the disease is needed. However, both ultrasonic duplex scanning and renal scintigraphy are not sufficient for detection of all stenosis. Furthermore, there is little data on non-invasive tests in patients with rena

The significance of serpins in the regulation of proteases in the male genital tract

The male genital tract is rich in proteases, delivered by the male accessory sex glands, that are delicately balanced in their action by serpins, non-serpin class protease inhibitors and other regulatory mechanisms. Still, the biological function of the serpins and their target enzymes in the male genital tract and possible involvement in the regulation of normal reproductive function mainly remai

Similar treatment success rate after renal transplantation in diabetic and nondiabetic patients due to improved short- and long-term diabetic patient survival

In the early era of transplantation, it was common practice to exclude diabetic patients since the outcome in such cases was usually poor. At our center in Malmö, Sweden, diabetic nephropathy was never regarded as a contraindication. During the 22-year period from 1972 to 1993, 223 renal allografts were transplanted in 189 uremic diabetics, representing 24% of all renal transplant recipients (n =

Free and complexed prostate-specific antigen (PSA) : in vitro stability, epitope map, and development of immunofluorometric assays for specific and sensitive detection of free PSA and PSA-alpha 1-antichymotrypsin complex

Generation of 15 monoclonal antibodies (MAbs) allowed construction of epitope maps and specific two-site immunofluorometric assays for free prostate-specific antigen (PSA) and PSA complexed with alpha 1-antichymotrypsin (ACT). Close correlation of PSA concentrations obtained with the use of different assays of free PSA suggested extensive similarity in immunodetection of free PSA in serum. Assays

Protein C inhibitor in human body fluids. Seminal plasma is rich in inhibitor antigen deriving from cells throughout the male reproductive system

An assay was developed for the measurement of human protein C inhibitor antigen (PCI) in blood plasma and other biological fluids. Both native PCI, modified inhibitor, and complexes of inhibitor with activated protein C or plasma kallikrein could be measured with the assay. Inhibitor antigen concentrations were found to be very high in seminal plasma (greater than 200 mg/liter), more than 40 times

Prostate-specific antigen in serum occurs predominantly in complex with alpha 1-antichymotrypsin

Immunologic measurements of the serum concentration of prostate-specific antigen (PSA), an abundant prostatic-secreted serine proteinase, are frequently used to monitor patients with prostate cancer, though it has not been ascertained whether this immunoreactivity represents a PSA zymogen, the active proteinase, or PSA complexed to extracellular proteinase inhibitors. To characterize the PSA immun

Sociolinguistic, comparative and historical perspectives on Scandinavian gender: With focus on Jamtlandic

The present thesis investigates gender assignment in Jamtlandic from a sociolinguistic and historical/comparative perspective. Jamtlandic is a language variety spoken in northwestern Sweden in the province of Jämtland. It maintains a three-gender system, in contrast to Standard Swedish, which has a two-gender system. Study 1 of the thesis looks at Jamtlandic gender assignment from a sociolinguisti

In vivo comparative evaluation of hemodialysis tubing plasticized with DEHP and TEHTM

The migration of plasticizers from blood lines was studied in 11 patients with chronic renal failure on hemodialysis for a period of six months. Di-2-ethylhexylphthalate (DEHP), the conventional plasticizer, was compared with tri-2-ethylhexyltrimellitate (TEHTM). A liquid chromatography method for quantitative determination of DEHP and TEHTM in human blood plasma is described. During treatment wit